Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Cell Stem Cell - Tập 6 Số 1 - Trang 25-36 - 2010
Nick Barker1, Meritxell Huch1, Pekka Kujala2, Marc van de Wetering1, Hugo J.G. Snippert1, Johan H. van Es1, Toshiro Sato1, Daniel E. Stange1, Harry Begthel1, Maaike van den Born1, Esther Danenberg1, Stieneke van den Brink1, Jeroen Korving1, Arie Abo3, Peter J. Peters2,4, Nicholas A. Wright5, Richard Poulsom6, Hans Clevers1
1Hubrecht Institute for Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584CT Utrecht & University Medical Centre Utrecht, Netherlands
2Antoni van Leeuwenhoek Hospital/Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands
3Nuvelo, Inc., 201 Industrial Road, Suite 310, San Carlos, CA 94070-6211, USA
4Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands
5Barts and the London School of Medicine and Dentistry, Garrod Building, Turner Street, London E1 2AD, UK
6Cancer Research UK - London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK

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