Large and Sustained Induction of Chemokines during Impaired Wound Healing in the Genetically Diabetic Mouse: Prolonged Persistence of Neutrophils and Macrophages during the Late Phase of Repair

Asagoe, 1998, Down-regulation of, CXCR, 2 expression on human polymorphonuclear leukocytes by, TNF, -alpha, J Immunol, 160, 4518, 10.4049/jimmunol.160.9.4518

Baggiolini, 1998, Chemokines and leukocyte traffic, Nature, 392, 565, 10.1038/33340

Barker, 1991, Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes, Am J Pathol, 139, 869

Bennett, 1993, Growth factors and wound healing: Part II. Role in normal and chronic wound healing, Am J Surg, 166, 74, 10.1016/S0002-9610(05)80589-6

Chen, 1996, Evidence that the diabetes gene encodes the leptin receptor. identification of a mutation in the leptin receptor gene in db/db mice, Cell, 84, 491, 10.1016/S0092-8674(00)81294-5

Chomczynski, 1987, Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal Biochem, 162, 156, 10.1016/0003-2697(87)90021-2

Clark, 1996, Wound repair: overview and general considerations, 3

Coleman, 1982, Diabetes–obesity syndromes in mice, Diabetes, 31, 1, 10.2337/diab.31.1.S1

Cross, 1988, Mouse lysozyme M gene: isolation, characterization, and expression studies, Proc Natl Acad Sci USA, 85, 6232, 10.1073/pnas.85.17.6232

DiPietro, 1995, Wound healing: the role of the macrophage and other immune cells, Shock, 4, 233, 10.1097/00024382-199510000-00001

DiPietro, 1998, MIP-1α as a critical macrophage chemoattractant in murine wound repair, J Clin Invest, 101, 1693, 10.1172/JCI1020

DiPietro, 1995, Modulation of JE/MCP-1 expression in dermal wound repair, Am J Pathol, 146, 868

Engelhardt, 1998, Chemokines IL-8, GROα MCP-1, IP-10, and Mig are sequentially and differentially expressed during phase-specific infiltration of leukocyte subsets in human wound healing, Am J Pathol, 153, 1849, 10.1016/S0002-9440(10)65699-4

Fantuzzi, 1999, Loss of CCR2 expression and functional response to monocyte chemotactic protein (MCP-1) during the differentiation of human monocytes: role of secreted MCP-1 in the regulation of the chemotactic response, Blood, 94, 875, 10.1182/blood.V94.3.875.415k28_875_883

Garay-Rojas, 1996, An apparent autocrine mechanism amplifies the dexamethasone- and retinoic acid-induced expression of mouse lipocalin encoding gene 24p3, Gene, 170, 173, 10.1016/0378-1119(95)00896-9

Gibran, 1997, Monocyte chemoattractant protein-1 mRNA expression in the human burn wound, J Surg Res, 70, 1, 10.1006/jsre.1997.5017

Goodson, 1979, Wound healing and the diabetic patient, Surg Gyn Obstet, 149, 600

Gray, 1986, Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1-beta, J Immunol, 137, 3644, 10.4049/jimmunol.137.11.3644

Greenhalgh, 1990, PDGF and FGF stimulate wound healing in the genetically diabetic mouse, Am J Pathol, 136, 1235

Gyulai, 1994, Chemotaxis of freshly separated and cultured human keratinocytes, Clin Exp Dermatol, 19, 309, 10.1111/j.1365-2230.1994.tb01201.x

Harada, 1994, Cloning of a cDNA encoding a mouse homolog of the interleukin-8 receptor, Gene, 142, 297, 10.1016/0378-1119(94)90278-X

Heesen, 1996, Mouse astrocytes respond to the chemokine MCP-1 and KC, but reverse transcriptase-polymerase chain reaction does not detect mRNA for the KC or new MCP-1 receptor, J Neurosci Res, 45, 382, 10.1002/(SICI)1097-4547(19960815)45:4<382::AID-JNR7>3.0.CO;2-5

Hübner, 1996, Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice, Cytokine, 8, 548, 10.1006/cyto.1996.0074

Iida, 1990, Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue, Mol Cell Biol, 10, 5596, 10.1128/MCB.10.10.5596

Knighton, 1993, Growth factors and repair of diabetic wounds, 247

Kulke, 1998, The CXC receptor 2 is overexpressed in psoriatic epidermis, J Invest Dermatol, 110, 90, 10.1046/j.1523-1747.1998.00074.x

Kurosaka, 1998, Production of proinflammatory cytokines by phorbol myristate acetate-treated THP-1 cells and monocyte-derived macrophages after phagocytosis of apoptotic CTLL-2 cells, J Immunol, 161, 6245, 10.4049/jimmunol.161.11.6245

Lee, 1996, Abnormal splicing of the leptin receptor in diabetic mice, Nature, 379, 632, 10.1038/379632a0

Leibovich, 1975, The role of the macrophage in wound repair: a study with hydrocortisone and anti-macrophage serum, Am J Pathol, 78, 71

Loots, 1998, Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds, J Invest Dermatol, 111, 850, 10.1046/j.1523-1747.1998.00381.x

Luster, 1998, Chemokines – chemotactic cytokines that mediate inflammation, New Engl J Med, 338, 436, 10.1056/NEJM199802123380706

Martin, 1997, Wound healing – aiming for perfect skin regeneration, Science, 276, 75, 10.1126/science.276.5309.75

Michel, 1992, Interleukin-8-receptor-mediated chemotaxis of normal human epidermal cells, FEBS Lett, 305, 241, 10.1016/0014-5793(92)80677-9

Moore, 1997, Lymphocytes and the lack of activated macrophages in wound margin biopsies from chronic leg ulcers, Br J Dermatol, 137, 188, 10.1046/j.1365-2133.1997.18041895.x

Murdoch, 1999, CXC chemokine receptor expression on human endothelial cells, Cytokine, 11, 704, 10.1006/cyto.1998.0465

Murphy, 1996, Chemokine receptors: structure, function and role in microbial pathogenesis, Cytokine Growth Fact Res, 7, 47, 10.1016/1359-6101(96)00009-3

Pennica, 1985, Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor, Proc Natl Acad Sci USA, 82, 6060, 10.1073/pnas.82.18.6060

Rollins, 1997, Chemokines, Blood, 90, 909, 10.1182/blood.V90.3.909

Rollins, 1988, Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties, Proc Natl Acad Sci USA, 85, 3738, 10.1073/pnas.85.11.3738

Rollins, 1990, Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE, Am J Pathol, 136, 1229

Rosner, 1995, Immunohistochemical characterization of the cutaneous cellular infiltrate in different areas of chronic leg ulcers, APMIS, 103, 293, 10.1111/j.1699-0463.1995.tb01109.x

Strieter, 1989, Monocyte chemotactic protein gene expression by cytokine-treated human fibroblasts and endothelial cells, Biochem Biophys Res Commun, 162, 694, 10.1016/0006-291X(89)92366-8

Tekamp-Olson, 1990, Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues, J Exp Med, 172, 911, 10.1084/jem.172.3.911

Tsuboi, 1990, Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice, J Exp Med, 172, 245, 10.1084/jem.172.1.245

Uchimura, 1997, Interaction of phagocytes with apoptotic cells leads to production of pro-inflammatory cytokines, Biochem Biophys Res Commun, 239, 799, 10.1006/bbrc.1997.7556

Weber, 1999, Atherosclerosis, 145, 115, 10.1016/S0021-9150(99)00021-0

Weber, 1999, Expression of CCR2 by endothelial cells: implications for MCP-1 mediated wound injury repair and in vivo inflammatory activation of endothelium, Arterioscler Thromb Vasc Biol, 19, 2085, 10.1161/01.ATV.19.9.2085

Werner, 1992, Large induction of keratinocyte growth factor expression in the dermis during wound healing, Proc Natl Acad Sci USA, 89, 6896, 10.1073/pnas.89.15.6896