La suplementación con ácidos grasos mejora parámetros respiratorios, inflamatorios y nutricionales en adultos con fibrosis quística

Christophe, 2001, Directed modification instead of normalization of fatty acid patterns in cystic fibrosis: An emerging concept, Curr Opin Clin Nutr Metab Care., 4, 111, 10.1097/00075197-200103000-00005 Lepage, 2002, Effect of an organized lipid matrix on lipid absorption and clinical outcomes in patients with cystic fibrosis, J Pediatr., 141, 178, 10.1067/mpd.2002.124305 Olveira, 2006, Serum phospholipid fatty acid profile and dietary intake in an adult Mediterranean population with cystic fibrosis, Br J Nutr., 96, 343, 10.1079/BJN20051655 Van Biervliet, 2008, Oral DHA supplementation in DeltaF508 homozygous cystic fibrosis patients, Prostaglandins Leukot Essent Fatty Acids., 78, 109, 10.1016/j.plefa.2007.12.005 Freedman, 1999, A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr (-/-) mice, Proc Natl Acad Sci USA., 96, 13995, 10.1073/pnas.96.24.13995 Freedman, 2004, Association of cystic fibrosis with abnormalities in fatty acid metabolism, N Engl J Med., 350, 560, 10.1056/NEJMoa021218 Strandvik, 2001, Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis, J Pediatr., 138, 650, 10.1067/mpd.2001.118890 Christophe, 1994, Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis, Ann Nutr Metab., 38, 40, 10.1159/000177792 Christophe, 1992, Increase of long chain omega-3 fatty acids in the major serum lipid classes of patients with cystic fibrosis, Ann Nutr Metab., 36, 304, 10.1159/000177734 De Vizia, 2003, Effect of an 8-month treatment with omega-3 fatty acids (eicosapentaenoic and docosahexaenoic) in patients with cystic fibrosis, J Parenter Enteral Nutr., 27, 52, 10.1177/014860710302700152 Katz, 1996, The use of an intravenous fish oil emulsion enriched with omega-3 fatty acids in patients with cystic fibrosis, Nutrition., 12, 334, 10.1016/S0899-9007(96)80056-6 Henderson, 1994, Oral absorption of omega-3 fatty acids in patients with cystic fibrosis who have pancreatic insufficiency and in healthy control subjects, J Pediatr., 124, 400, 10.1016/S0022-3476(94)70362-0 Lawrence, 1994, Eicosapentaenoic acid modulates neutrophil leukotriene B4 receptor expression in cystic fibrosis, Clin Exp Immunol., 98, 12, 10.1111/j.1365-2249.1994.tb06599.x Kurlandsky, 1994, The absorption and effect of dietary supplementation with omega-3 fatty acids on serum leukotriene B4 in patients with cystic fibrosis, Pediatr Pulmonol., 18, 211, 10.1002/ppul.1950180404 Thies, 1997, The effect of 12 months’ treatment with eicosapentaenoic acid in five children with cystic fibrosis, J Paediatr Child Health., 33, 349, 10.1111/j.1440-1754.1997.tb01615.x Lloyd-Still, 2006, Bioavailability and safety of a high dose of docosahexaenoic acid triacylglycerol of algal origin in cystic fibrosis patients: A randomized, controlled study, Nutrition., 22, 36, 10.1016/j.nut.2005.05.006 Jumpsen, 2006, Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis, J Cyst Fibros., 5, 77, 10.1016/j.jcf.2006.01.004 Panchaud, 2006, Biological effects of a dietary omega-3 polyunsaturated fatty acids supplementation in cystic fibrosis patients: A randomized, crossover placebo controlled trial, Clin Nutr., 25, 418, 10.1016/j.clnu.2005.10.011 Durieu, 2007, Fatty acids platelets and oxidative markers following intravenous n-3 fatty acids administration in cystic fibrosis: An open pilot observational study, J Cyst Fibros., 6, 320, 10.1016/j.jcf.2006.12.005 Lloyd-Still, 1991, Essential fatty acid status and fluidity of plasma phospholipids in cystic fibrosis infants, Am J Clin Nutr., 54, 1029, 10.1093/ajcn/54.6.1029 Kerem, 2005, Standards of care for patients with cystic fibrosis: A European consensus, J Cystic Fibros., 4, 7, 10.1016/j.jcf.2004.12.002 Soriguer, 2006, Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid, J Nutr., 136, 2325, 10.1093/jn/136.9.2325 Roca, 1986, Spirometric reference values for a Mediterranean population, Bull Eur Physiopathol Respir., 18, 101 Sockrider, 1994, Measuring clinical status in cystic fibrosis: Internal validity and reliability of a modified NIH score, Pediatr Pulmonol., 17, 86, 10.1002/ppul.1950170204 Bhalla, 1991, Cystic fibrosis: Scoring system with thin-section CT, Radiology., 179, 783, 10.1148/radiology.179.3.2027992 Vendrell, 2008, Normativa SEPAR: diagnóstico y tratamiento de las bronquiectasias, Arch Bronconeumol., 44, 629, 10.1157/13128330 Alastrué, 1983, Valoración antropométrica del estado de nutrición: normas y criterios de desnutrición y obesidad, Med Clín (Barc)., 80, 691 Durnin, 1974, Body fat assessed from total body density and its estimation from skinfold thickness: Measurements on 481 men and women aged from 16 to 72 years, Br J Nutr., 32, 77, 10.1079/BJN19740060 Siri, 1961, Body composition from fluid spaces and density: Analysis of methods, 223 Olveira, 2009, Markers for the validation of reported dietary intake in adults with cystic fibrosis, J Am Diet Assoc., 109, 1704, 10.1016/j.jada.2009.07.012 Ramsey, 1992, Nutritional assessment and management in cystic fibrosis: A consensus report. The Consensus Committee, Am J Clin Nutr., 55, 106, 10.1093/ajcn/55.1.108 Tinahones, 2005, Influence of age and sex on levels of anti-oxidized LDL antibodies and anti-LDL immune complexes in the general population, J Lipid Res., 46, 452, 10.1194/jlr.M400290-JLR200 Padilla, 2007, Validity and reliability of the St. George's Respiratory Questionnaire in adults with cystic fibrosis, Arch Bronconeumol., 43, 205, 10.1157/13100539 Harris, 2007, Comparison of the effects of fish and fish-oil capsules on the n 3 fatty acid content of blood cells and plasma phospholipids, Am J Clin Nutr., 86, 1621, 10.1093/ajcn/86.6.1621 Van Biervliet, 2005, Docosahexaenoic acid trials in cystic fibrosis: A review of the rationale behind the clinical trials, J Cyst Fibros., 4, 27, 10.1016/j.jcf.2004.11.001 Keen, 2007, Airway nitric oxide in patients with cystic fibrosis is associated with pancreatic function, pseudomonas infection, and polyunsaturated fatty acids, Chest., 131, 1857, 10.1378/chest.06-2635 Schmitt-Grohé, 2006, Serum leptin and cytokines in whole blood in relation to clinical and nutritional status in cystic fibrosis, J Pediatr Gastroenterol Nutr., 43, 228, 10.1097/01.mpg.0000228096.81831.a2 Ionescu, 2002, Pulmonary function, body composition, and protein catabolism in adults with cystic fibrosis, Am J Respir Crit Care Med., 165, 495, 10.1164/ajrccm.165.4.2104065 Martínez-García, 2008, The association between bronchiectasis, sistemic inflammation and tumor necrosis factor alpha, Arch Bronconeumol., 44, 8, 10.1157/13114651 Wood, 2001, Oxidative stress in cystic fibrosis: Dietary and metabolic factors, J Am Coll Nutr., 20, 157, 10.1080/07315724.2001.10719028 McKarney, 2007, Omega-3 fatty acids (from fish oils) for cystic fibrosis, Cochrane Database of Systematic Reviews.