Knee donor-site morbidity after mosaicplasty – a systematic review

Journal of Experimental Orthopaedics - Tập 3 - Trang 1-17 - 2016
Renato Andrade1,2,3, Sebastiano Vasta4, Rogério Pereira1,2,3,5, Hélder Pereira6,7,8,9, Rocco Papalia4, Mustafa Karahan10, J. Miguel Oliveira2,7,11, Rui L. Reis7,11, João Espregueira-Mendes2,3,7,11,12
1Faculty of Sports, University of Porto, Porto, Portugal
2Clínica do Dragão, Espregueira-Mendes Sports Centre - FIFA Medical Centre of Excellence, Porto, Portugal
3Dom Henrique Research Centre, Porto, Portugal
4Orthopaedic and Trauma Department, Campus Biomedico University of Rome, Rome, Italy
5Faculty of Health Sciences, University of Fernando Pessoa, Porto, Portugal
6Orthopaedic Department, Centro Hospitalar Póvoa de Varzim, Vila do Conde, Portugal
73B’s Research Group–Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal
8ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal
9Ripoll y De Prado Sports Clinic FIFA Medical Centre of Excellence, Murcia-Madrid, Spain
10Department of Orthopaedic Surgery, Acibadem University, Istanbul, Turkey
11ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal
12Orthopaedics Department of Minho University, Minho, Portugal

Tóm tắt

Mosaicplasty has been associated with good short- to long-term results. Nevertheless, the osteochondral harvesting is restricted to the donor-site area available and it may lead to significant donor-site morbidity. Provide an overview of donor-site morbidity associated with harvesting of osteochondral plugs from the knee joint in mosaicplasty procedure. Comprehensive search using Pubmed, Cochrane Library, SPORTDiscus and CINAHL databases was carried out through 10th October of 2016. As inclusion criteria, all English-language studies that assessed the knee donor-site morbidity after mosaicplasty were accepted. The outcomes were the description and rate of knee donor-site morbidity, sample’s and cartilage defect’s characterization and mosaicplasty-related features. Correlation between mosaicplasty features and rate of morbidity was performed. The methodological and reporting quality were assessed according to Coleman’s methodology score. Twenty-one studies were included, comprising a total of 1726 patients, with 1473 and 268 knee and ankle cartilage defects were included. The defect size ranged from 0.85 cm2 to 4.9 cm2 and most commonly 3 or less plugs (averaging 2.9 to 9.4 mm) were used. Donor-site for osteochondral harvesting included margins of the femoral trochlea (condyles), intercondylar notch, patellofemoral joint and upper tibio-fibular joint. Mean donor-site morbidity was 5.9 % and 19.6 % for knee and ankle mosaicplasty procedures, respectively. Concerning knee-to-knee mosaicplasty procedures, the most common donor-site morbidity complaints were patellofemoral disturbances (22 %) and crepitation (31 %), and in knee-to-ankle procedures there was a clear tendency for pain or instability during daily living or sports activities (44 %), followed by patellofemoral disturbances, knee stiffness and persistent pain (13 % each). There was no significant correlation between rate of donor-site morbidity and size of the defect, number and size of the plugs (p > 0.05). Osteochondral harvesting in mosaicplasty often results in considerable donor-site morbidity. The donor-site morbidity for knee-to-ankle (16.9 %) was greater than knee-to-knee (5.9 %) mosaicplasty procedures, without any significant correlation between rate of donor-site morbidity and size of the defect, number and size of the plugs. Lack or imcomplete of donor-site morbidity reporting within the mosaicplasty studies is a concern that should be addressed in future studies. Level IV, systematic review of Level I-IV studies.

Tài liệu tham khảo

Ahmad J, Jones K (2015) Comparison of osteochondral autografts and allografts for treatment of recurrent or large talar osteochondral lesions. Foot Ankle Int. doi:10.1177/1071100715603191

Al-Shaikh RA, Chou LB, Mann JA, Dreeben SM, Prieskorn D (2002) Autologous osteochondral grafting for talar cartilage defects. Foot Ankle Int 23(5):381–389

Atik OS, Uslu MM, Eksioglu F (2005) Osteochondral multiple autograft transfer (OMAT) for the treatment of cartilage defects in the knee joint. Bull Hosp Jt Dis 63(1-2):37–40

Baltzer AW, Arnold JP (2005) Bone-cartilage transplantation from the ipsilateral knee for chondral lesions of the talus. Arthroscopy 21(2):159–166

Bartha L, Vajda A, Duska Z, Rahmeh H, Hangody L (2006) Autologous osteochondral mosaicplasty grafting. J Orthop Sports Phys Ther 36(10):739–750

Bartha L, Hamann D, Pieper J, Peters F, Riesle J, Vajda A, Novak PK, Hangody LR, Vasarhelyi G, Bodo L, van Blitterswijk C, de Wijn J, Kenyeres A, Modis L, Balo E, Hangody L (2013) A clinical feasibility study to evaluate the safety and efficacy of PEOT/PBT implants for human donor site filling during mosaicplasty. Eur J Orthop Surg Traumatol 23(1):81–91

Bedi A, Feeley BT, Williams R 3rd (2010) Management of articular cartilage defects of the knee. J Bone Joint Surg Am 92(4):994–1009

Braun BJ, Brandenburg LO, Braun C (2012) Treatment of a partial avascular necrosis of a metacarpal head (Morbus Mauclaire Dieterich’s Disease) utilizing the ostechondral autograft transfer system (OATS) technique. Handchir Mikrochir Plast Chir 44(1):35–39

Calder JD, Ballal MS, Deol RS, Pearce CJ, Hamilton P, Lutz M (2015) Histological evaluation of calcaneal tuberosity cartilage--A proposed donor site for osteochondral autologous transplant for talar dome osteochondral lesions. Foot Ankle Surg 21(3):193–197

Clavé A, Potel JF, Servien E, Neyret P, Dubrana F, Stindel E (2016) Third‐generation autologous chondrocyte implantation versus mosaicplasty for knee cartilage injury: 2‐year randomized trial. J Orthop Res 34(4):658–665

Coleman B, Khan K, Maffulli N, Cook J, Wark J (2000) Studies of surgical outcome after patellar tendinopathy: clinical significance of methodological deficiencies and guidelines for future studies. Scand J Med Sci Sports 10(1):2–11

de l'Escalopier N, Barbier O, Mainard D, Mayer J, Ollat D, Versier G (2015) Outcomes of talar dome osteochondral defect repair using osteocartilaginous autografts: 37 cases of Mosaicplasty(R). OTSR 101(1):97–102

Espregueira-Mendes J, Pereira H, Sevivas N, Varanda P, da Silva MV, Monteiro A, Oliveira JM, Reis RL (2012) Osteochondral transplantation using autografts from the upper tibio-fibular joint for the treatment of knee cartilage lesions. Knee Surg Sports Traumatol Arthrosc 20(6):1136–1142

Feczkó P, Hangody L, Varga J, Bartha L, Diószegi Z, Bodó G, Kendik Z, Módis L (2003) Experimental results of donor site filling for autologous osteochondral mosaicplasty. Arthroscopy 19(7):755–761

Gautier E, Kolker D, Jakob R (2002) Treatment of cartilage defects of the talus by autologous osteochondral grafts. J Bone Joint Surg Br 84(2):237–244

Gomoll AH, Minas T (2014) The quality of healing: articular cartilage. Wound Repair Regen 22(S1):30–38

Gomoll A, Filardo G, De Girolamo L, Esprequeira-Mendes J, Marcacci M, Rodkey W, Steadman R, Zaffagnini S, Kon E (2012) Surgical treatment for early osteoarthritis. Part I: cartilage repair procedures. Knee Surg Sports Traumatol Arthrosc 20(3):450–466

Gudas R, Kalesinskas RJ, Kimtys V, Stankevicius E, Toliusis V, Bernotavicius G, Smailys A (2005) A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy 21(9):1066–1075

Gwilym S, Swan M, Giele H (2004) One in 13 ‘original’articles in the Journal of Bone and Joint Surgery are duplicate or fragmented publications. J Bone Joint Surg Br 86(5):743–745

Han K-J, Oh K-S, Chung N-S, Lee YS, Youn S (2012) Radial head arthroplasty using a metatarsal osteochondral autograft. Int Orthop 36(12):2501–2506

Hangody L, Füles P (2003) Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints. J Bone Joint Surg Am 85(suppl 2):25–32

Hangody L, Karpati Z (1993) New possibilities in the management of severe circumscribed cartilage damage in the knee. Magy Traumatol Ortop Kezseb Plasztikai Seb 37:237–43

Hangody L, Kish G, Karpati Z, Szerb I, Udvarhelyi I (1997) Arthroscopic autogenous osteochondral mosaicplasty for the treatment of femoral condylar articular defects A preliminary report. Knee Surg Sports Traumatol Arthrosc 5(4):262–267

Hangody L, Kish G, Modis L, Szerb I, Gaspar L, Dioszegi Z, Kendik Z (2001a) Mosaicplasty for the treatment of osteochondritis dissecans of the talus: two to seven year results in 36 patients. Foot Ankle Int 22(7):552–558

Hangody L, Feczkó P, Bartha L, Bodó G, Kish G (2001b) Mosaicplasty for the treatment of articular defects of the knee and ankle. Clin Orthop Relat Res 391:S328–S336

Hangody L, Vasarhelyi G, Hangody LR, Sukosd Z, Tibay G, Bartha L, Bodo G (2008) Autologous osteochondral grafting - technique and long-term results. Injury 39(Suppl 1):S32–39

Hangody L, Dobos J, Balo E, Panics G, Hangody LR, Berkes I (2010) Clinical experiences with autologous osteochondral mosaicplasty in an athletic population: a 17-year prospective multicenter study. Am J Sports Med 38(6):1125–1133

Heijink A, Gomoll AH, Madry H, Drobnič M, Filardo G, Espregueira-Mendes J, Van Dijk CN (2012) Biomechanical considerations in the pathogenesis of osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc 20(3):423–435

Iwasaki N, Kato H, Kamishima T, Suenaga N, Minami A (2007) Donor site evaluation after autologous osteochondral mosaicplasty for cartilaginous lesions of the elbow joint. Am J Sports Med 35(12):2096–2100

Iwasaki N, Kato H, Ishikawa J, Masuko T, Funakoshi T, Minami A (2009) Autologous osteochondral mosaicplasty for osteochondritis dissecans of the elbow in teenage athletes. J Bone Joint Surg Am 91(10):2359–2366

Jakob RP, Franz T, Gautier E, Mainil-Varlet P (2002) Autologous osteochondral grafting in the knee: indication, results, and reflections. Clin Orthop Relat Res 401:170–184

Jakobsen RB, Engebretsen L, Slauterbeck JR (2005) An analysis of the quality of cartilage repair studies. J Bone Joint Surg Am 87(10):2232–2239

Kim S-J, Shin S-J (2000) Loose bodies after arthroscopic osteochondral autograft in osteochondritis dissecans of the knee. Arthroscopy 16(7):1–4

Kim YS, Park EH, Kim YC, Koh YG, Lee JW (2012) Factors associated with the clinical outcomes of the osteochondral autograft transfer system in osteochondral lesions of the talus second-look arthroscopic evaluation. Am J Sports Med 40(12):2709–2719

Kock NB, van Tankeren E, Oyen WJ, Wymenga AB, van Susante JL (2010) Bone scintigraphy after osteochondral autograft transplantation in the knee: 13 patients followed for 4 years. Acta Orthop 81(2):206–210

Kordás G, Szabó JS, Hangody L (2005) The effect of drill-hole length on the primary stability of osteochondral grafts in mosaicplasty. Orthopedics 28(4):401–404

Koulalis D, Schultz W, Heyden M, König F (2004) Autologous osteochondral grafts in the treatment of cartilage defects of the knee joint. Knee Surg Sports Traumatol Arthrosc 12(4):329–334

Kreuz P, Steinwachs M, Edlich M, Kaiser T, Mika J, Lahm A, Südkamp N (2006) The anterior approach for the treatment of posterior osteochondral lesions of the talus: comparison of different surgical techniques. Arch Orthop Trauma Surg 126(4):241–246

Krych AJ, Gobbi A, Lattermann C, Nakamura N (2016) Articular cartilage solutions for the knee: present challenges and future direction. J ISAKOS 1(2):93–104

LaPrade RF, Botker JC (2004) Donor-site morbidity after osteochondral autograft transfer procedures. Arthroscopy 20(7):e69–73

Lee CH, Chao KH, Huang GS, Wu SS (2003) Osteochondral autografts for osteochondritis dissecans of the talus. Foot Ankle Int 24(11):815–822

Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux P, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med 151(4):W-65-W-94

Lynch TS, Patel RM, Benedick A, Amin NH, Jones MH, Miniaci A (2015) Systematic review of autogenous osteochondral transplant outcomes. Arthroscopy 31(4):746–754

Lyons ML, Werner BC, Gluck JS, Freilich AM, Dacus AR, Diduch DR, Chhabra AB (2015) Osteochondral autograft plug transfer for treatment of osteochondritis dissecans of the capitellum in adolescent athletes. J Shoulder Elbow Surg 24(7):1098–1105

McAdams TR, Mithoefer K, Scopp JM, Mandelbaum BR (2010) Articular cartilage injury in athletes. Cartilage 1(3):165–179

Moran CJ, Pascual-Garrido C, Chubinskaya S, Potter HG, Warren RF, Cole BJ, Rodeo SA (2014) Restoration of articular cartilage. J Bone Joint Surg Am 96(4):336–344

Mundi R, Bedi A, Chow L, Crouch S, Simunovic N, Enselman ES, Ayeni OR (2015) Cartilage Restoration of the knee a systematic review and meta-analysis of level 1 studies. Am J Sports Med:0363546515589167

Nakagawa Y, Suzuki T, Matsusue Y, Kuroki H, Mizuno Y, Nakamura T (2005) Bony lesion recurrence after mosaicplasty for osteochondritis dissecans of the talus. Arthroscopy 21(5):630. e631–630. e635

Nishimura A, Morita A, Fukuda A, Kato K, Sudo A (2011) Functional recovery of the donor knee after autologous osteochondral transplantation for capitellar osteochondritis dissecans. Am J Sports Med 39(4):838–842

Paul J, Sagstetter A, Kriner M, Imhoff A, Spang J, Hinterwimmer S (2009) Donor-site morbidity after osteochondral autologous transplantation for lesions of the talus. J Bone Joint Surg Am 91(7):1683–1688

Peterson L (2003) Chondrocyte Implantation. In: Jackson DW (ed) Master Techniques in Orthopaedic Surgery: Reconstructive KneeSurgery. Lippincott, Williams & Wilkins, Philadelphia

Quarch VM, Enderle E, Lotz J, Frosch KH (2014) Fate of large donor site defects in osteochondral transfer procedures in the knee joint with and without TruFit plugs. Arch Orthop Trauma Surg 134(5):657–666

Reddy S, Pedowitz DI, Parekh SG, Sennett BJ, Okereke E (2007) The morbidity associated with osteochondral harvest from asymptomatic knees for the treatment of osteochondral lesions of the talus. Am J Sports Med 35(1):80–85

Reverte-Vinaixa MM, Joshi N, Diaz-Ferreiro EW, Teixidor-Serra J, Dominguez-Oronoz R (2013) Medium-term outcome of mosaicplasty for grade III-IV cartilage defects of the knee. J Orthop Surg (Hong Kong) 21(1):4–9

Schein M, Paladugu R (2001) Redundant surgical publications: tip of the iceberg? Surgery 129(6):655–661

Shimada K, Yoshida T, Nakata K, Hamada M, Akita S (2005) Reconstruction with an osteochondral autograft for advanced osteochondritis dissecans of the elbow. Clin Orthop Relat Res 435:140–147

Simon T, Jackson D (2006) Articular cartilage: injury pathways and treatment options. Sports Med Arthrosc 14(3):146–154

Steinwachs M, Engebretsen L, Brophy R (2012) Scientific evidence base for cartilage injury and repair in the athlete. Cartilage 3(1 suppl):11S–17S

Szerb I, Hangody L, Duska Z, Kaposi NP (2005) Mosaicplasty: long-term follow-up. Bull NYU Hosp Jt Dis 63(1-2):54–54

Thaunat M, Beaufils P (2010) The posterior femoral condyles: a potential donor site for mosaic-like osteochondral autograft? Arthroscopy 26(11):1503–1509

Tsuda E, Ishibashi Y, Sato H, Yamamoto Y, Toh S (2005) Osteochondral autograft transplantation for osteochondritis dissecans of the capitellum in nonthrowing athletes. Arthroscopy 21(10):1270

Tytherleigh-Strong G, Miniaci A (2003) Arthroscopic autogenous osteochondral graft fixation (mosaicplasty) of unstable osteochondritis dissecans lesions of the knee. J Bone Joint Surg Br 85(SUPP II):105–106

Valderrabano V, Leumann A, Rasch H, Egelhof T, Hintermann B, Pagenstert G (2009) Knee-to-ankle mosaicplasty for the treatment of osteochondral lesions of the ankle joint. Am J Sports Med 37(Suppl 1):105s–111s

Vezeridis AM, Bae DS (2016) Evaluation of knee donor and elbow recipient sites for osteochondral autologous transplantation surgery in capitellar osteochondritis dissecans. Am J Sports Med 44(2):511–520

Zelent ME, Neese DJ (2005) Osteochondral autograft transfer of the first metatarsal head: a case report. J Foot Ankle Surg 44(5):406–411

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Journal of Experimental Orthopaedics

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