KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

European Journal of Cancer - Tập 42 - Trang 1093-1103 - 2006
Maria Debiec-Rychter1, Raf Sciot2, Axel Le Cesne3, Marcus Schlemmer4, Peter Hohenberger5, Allan T. van Oosterom6, Jean-Yves Blay7, Serge Leyvraz8, Michel Stul1, Paolo G. Casali9, John Zalcberg10, Jaap Verweij11, Martine Van Glabbeke12, Anne Hagemeijer1, Ian Judson13
1Department of Human Genetics, University of Leuven and University Hospital Gasthuisberg, O&N Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium
2Department of Pathology, University of Leuven and University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium
3Institut Gustave Roussy, Villejuif, France
4Department of Medical Oncology, Klinikum Grosshadern, Munich and GSF – National Research Center for Environment and Health, Neuherberg, Germany
5Charité, Robert Roessle Klinik, Berlin, Germany
6Department of Medical Oncology, University of Leuven and University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium
7Centre Leon Berard, Lyon, France
8CHU Vaudois, Lausanne, Switzerland
9Instituto Nazionale Tumori, Milano, Italy
10Peter MacCallum Cancer Centre, Melbourne, Australia
11Erasmus University Medical Center, Rotterdam, The Netherlands;
12EORTC Data Center, Brussels, Belgium
13Royal Marsden Hospital, London, United Kingdom

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