Investigation of SARS-CoV-2 in Semen of Patients in the Acute Stage of COVID-19 Infection

Urologia Internationalis - Tập 104 Số 9-10 - Trang 678-683 - 2020
Bircan Kayaaslan1, Gülay Korukluoğlu2, İmran Hasanoğlu1, Ayşe Kaya Kalem1, Fatma Eser1, Esragül Akıncı3, Rahmet Güner1
1Infectious Disease and Clinical Microbiology, Ankara Yildırım Beyazit University, Ankara City Hospital, Ankara, Turkey
2Clinical Microbiology, Virology, National Virology Laboratory, Turkish Public Health Institution, Ankara, Turkey
3Infectious Disease and Clinical Microbiology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey

Tóm tắt

<b><i>Introduction:</i></b> The presence of new coronavirus (SARS-CoV-2) in semen and the possibility of sexual transmission have become new subjects of curiosity. There is a discrepancy regarding this issue in the literature. The presence of SARS-CoV-2 in semen has been investigated in a limited number of studies, and mostly in recovering patients. We aimed to investigate the presence of SARS-CoV-2 RNA in semen of patients with a positive nasopharyngeal swab test for SARS-CoV-2 in the acute stage. <b><i>Methods:</i></b> We enrolled adult male patients who were hospitalized with confirmed SARS-COV-2 infection in the study. In addition to routine laboratory and radiological tests, semen sample was obtained from volunteers and transferred to the Turkish Public Health Institution, National Virology Laboratory. The samples were processed for the detection of SARS-CoV-2 RNA on the day of collection. <b><i>Results:</i></b> Sixteen patients were included in the study. The median age was 33.5 years (18–54). All but one had respiratory symptoms. None of the patients had a history or symptoms of urogenital disease. All semen samples were obtained during hospitalization and in the acute stage of the infection. The median time to obtain a semen sample after positive nasopharyngeal test was 1 day (0–7). All semen samples were detected as negative for SARS-CoV-2 PCR. <b><i>Discussion/Conclusion:</i></b> Although all semen samples were obtained in acute stage of the infection when the nasopharyngeal swab test was positive, we did not detect SARS-CoV-2 in semen. The results of our study support the thought that sexual transmission via semen does not have an important role in the person-to-person transmission of SARS-CoV-2. We think that our study will provide new information to fill the gap in the literature.

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Urologia Internationalis

Tập 104 Số 9-10

678-683

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