Intrathecal pituitary adenylate cyclase activating polypeptide facilitates the spinal nociceptive flexor reflex in the rat

Arimura, 1992, Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research, Regul. Pept., 37, 287, 10.1016/0167-0115(92)90621-Z Arimura, 1992, Receptors for pituitary adenylate cyclase-activating polypeptide: comparison with vasoactive intestinal peptide receptors, trends Endocrinol. Metab., 3, 288, 10.1016/1043-2760(92)90139-R Cerne, 1992, Cyclic adenosine 3′5′-monophosphate potentiates excitatory amino acid and synaptic responses of rat dorsal horn neurons, Brain Res., 596, 111, 10.1016/0006-8993(92)91538-P Cerne, 1993, Enhancement of the N-methyl-d-aspartate response in spinal dorsal horn neurons by cAMP-dependent protein kinase, Neurosci. Left., 161, 124, 10.1016/0304-3940(93)90275-P Dickenson, 1990, Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat, Brain Res., 506, 31, 10.1016/0006-8993(90)91195-M Hua, 1991, The antinociceptive effects of spinally administered neuropeptide Y in the rat: systemic studies on structure-activity relationship, J. Pharmac. exp. Ther., 258, 243 Ishizuka, 1995, Facilitatory effect of pituitary adenylate cyclase activating polypeptide on micturition in normal conscious rats, Neuroscience, 66, 1009, 10.1016/0306-4522(95)00038-K Miyata, 1989, Isolation of a novel 38 residue-hypothalamic polypeptide which stimulate adenylate cyclase in pituitary cells, Biochem. biophys. Res. Commun., 164, 567, 10.1016/0006-291X(89)91757-9 Moller, 1993, Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: immunocytochemical and immunochemical evidence, Neuroscience, 57, 725, 10.1016/0306-4522(93)90018-B Post, 1988, Intrathecal galanin increases the latency in the tail flick and hot plate test in mouse, Acta Physiol. scand., 132, 583, 10.1111/j.1748-1716.1988.tb08369.x Tatsuno, 1992, Pituitary adenylate cyclase activating polypeptide increase cytosolic free calcium concentration in cultured rat hippocampal neurons, Endocrinology, 131, 73, 10.1210/en.131.1.73 Wall, 1984, Muscle, but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat, J. Physiol., 356, 443, 10.1113/jphysiol.1984.sp015475 Warren, 1992, Pituitary adenylate cyclase activating polypeptide is a potent vasodilator and oedema potentiator in rabbit skin, Br. J. Pharmac., 106, 331, 10.1111/j.1476-5381.1992.tb14336.x Wiesenfeld-Hallin, 1985, Intrathecal somatostatin modulates spinal sensory and reflex mechanisms: behavioral and electrophysiological studies in the rat, Neurosci. Lett., 62, 69, 10.1016/0304-3940(85)90286-1 Wiesenfeld-Hallin, 1987, Intrathecal vasoactive intestinal polypeptide modulates spinal reflex excitability primarily to cutaneous thermal stimuli in rats, Neurosci. Lett., 80, 293, 10.1016/0304-3940(87)90470-8 Wiesenfeld-Hallin, 1989, The effect of intrathecal galanin and C-fiber stimulation on the flexor reflex in the rat, Brain Res., 486, 205, 10.1016/0006-8993(89)90506-4 Woolf, 1986, Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat, Neurosci. Lett., 66, 319, 10.1016/0304-3940(86)90195-3 Woolf, 1991, The induction and maintainence of central sensitization is dependent on N-methyl-d-aspartic acid receptor activation: implications for the treatment of post-injury pain hypersensitivity states, Pain, 44, 293, 10.1016/0304-3959(91)90100-C Xu, 1992, Intrathecal CP-96,345 blocks reflex facilitation induced in rats by substance P and C-fiber-conditioning stimulation, Eur. J. Pharmac., 216, 337, 10.1016/0014-2999(92)90428-7 Xu, 1990, On the role of galanin, substance P and other neuropeptides in primary sensory neurons of the rat: studies on spinal reflex excitability and peripheral axotomy, Eur. J. Neurosci., 2, 733, 10.1111/j.1460-9568.1990.tb00464.x Xu, 1994, On the effects of intrathecal neuropeptide Y on the spinal nociceptive flexor reflex in rats with intact sciatic nerves and after peripheral axotomy, Neuroscience, 63, 817, 10.1016/0306-4522(94)90526-6 Yamamoto, 1995, Antinociceptive effect of intrathecally administered pituitary adenalyte cyclase activating polypeptide (PACAP) on the rat formalin test, Neurosci. Lett., 184, 32, 10.1016/0304-3940(94)11161-B Zhang, 1994, Pituitary adenylate cyclase activating peptide (PACAP) is upregulated in the rat dorsal root ganglia after peripheral nerve injuries, Abstr. Soc. Neurosci., 20, 1537 Zhang, 1993, Pituitary adenylate cyclase activating peptide produces a marked and long-lasting depression of a C-fibre-evoked flexion reflex, Neuroscience, 57, 733, 10.1016/0306-4522(93)90019-C