Intestinal helminth coinfection is associated with mucosal lesions and poor response to therapy in American tegumentary leishmaniasis

Acta Tropica - Tập 154 - Trang 42-49 - 2016
Rilza Beatriz Gayoso de Azeredo-Coutinho1, Maria Inês Fernandes Pimentel2, Graziela Maria Zaniní3, M.F. Madeira2, Jamyra Iglesias Cataldo2, Armando Schubach2, Leonardo Pereira Quintella4, Cíntia Xavier de Mello2, Sergio C.F. Mendonça5
1Secretaria Municipal de Saúde, Rua Afonso Cavalcanti, 455-Cidade Nova, 20211-110 Rio de Janeiro, Brazil.
2Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil 4365-Manguinhos, 21040-900 Rio de Janeiro, Brazil.
3Serviço de Parasitologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil 4365-Manguinhos, 21040-900 Rio de Janeiro, Brazil.
4Serviço de Anatomia Patológica, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil 4365-Manguinhos, 21040-900 Rio de Janeiro, Brazil.
5Laboratório de Imunoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Av. Brasil 4365-Manguinhos, 21040-360 Rio de Janeiro, Brazil. Electronic address: [email protected].

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Amato, 2003, Mucosal leishmaniasis: in situ characterization of the host inflammatory response, before and after treatment, Acta Trop., 85, 39, 10.1016/S0001-706X(02)00260-7

Azeredo-Coutinho, 2007, First report of diffuse cutaneous leishmaniasis and Leishmania amazonensis infection in Rio de Janeiro State, Brazil, Trans. R. Soc. Trop. Med. Hyg., 101, 735, 10.1016/j.trstmh.2007.01.005

Bacellar, 2002, Up-regulation of Th1-type responses in mucosal leishmaniasis patients, Infect. Immun., 70, 6734, 10.1128/IAI.70.12.6734-6740.2002

Bancroft, 1997, Interleukin-12 promotes a chronic intestinal nematode infection, Eur. J. Immunol., 27, 866, 10.1002/eji.1830270410

Carvalho, 2012, A comparative study of the TF-Test®, Kato-Katz, Hoffman-Pons-Janer, Willis and Baermann-Moraes coprologic methods for the detection of human parasitosis, Mem. Inst. Oswaldo Cruz, 107, 80, 10.1590/S0074-02762012000100011

Chan, 1997, The global burden of intestinal nematode infections-fifty years on, Parasitol. Today, 13, 438, 10.1016/S0169-4758(97)01144-7

Cooper, 2000, Human infection with Ascaris lumbricoides associated with a polarized cytokine response, J. Infect. Dis., 182, 1207, 10.1086/315830

Cooper, 1998, Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10, J. Infect. Dis., 178, 1133, 10.1086/515661

Coura, 1987, Disseminated American cutaneous leishmaniasis in a patient with AIDS, Mem. Inst. Oswaldo Cruz, 82, 581, 10.1590/S0074-02761987000400019

Cupolillo, 1994, A general classification of New World Leishmania using numerical zymotaxonomy, Am. J. Trop. Med. Hyg., 50, 296, 10.4269/ajtmh.1994.50.296

David, 2009, Cutaneous and mucocutaneous leishmaniasis, Dermatol. Ther., 22, 491, 10.1111/j.1529-8019.2009.01272.x

de Azeredo-Coutinho, 2002, An intermittent schedule is better than continuous regimen of antimonial therapy for cutaneous leishmaniasis in the municipality of Rio de Janeiro, Brazil, Rev. Soc. Bras. Med. Trop., 35, 477, 10.1590/S0037-86822002000500009

de Oliveira-Neto, 2000, American tegumentary leishmaniasis (ATL) in Rio de Janeiro State, Brazil: main clinical and epidemiologic characteristics, Int. J. Dermatol., 39, 506, 10.1046/j.1365-4362.2000.00969.x

Del Prete, 1998, The concept of type-1 and type-2 helper T cells and their cytokines in humans, Int. Rev. Immunol., 16, 427, 10.3109/08830189809043004

Delobel, 2003, American cutaneous leishmaniasis, lepromatous leprosy, and pulmonary tuberculosis coinfection with downregulation of the T-helper 1 cell response, Clin. Infect. Dis., 37, 628, 10.1086/376632

Elrefaei, 2003, HCV-specific CD27−CD28− memory T cells are depleted in hepatitis C virus and Schistosoma mansoni co-infection, Immunology, 110, 513, 10.1111/j.1365-2567.2003.01769.x

Else, 2005, Have gastrointestinal nematodes outwitted the immune system?, Parasite Immunol., 27, 407, 10.1111/j.1365-3024.2005.00788.x

Fagundes, 2010, Evaluation of polymerase chain reaction in the routine diagnosis for tegumentary leishmaniasis in a referral center, Mem. Inst. Oswaldo Cruz, 105, 109, 10.1590/S0074-02762010000100018

Faria, 2005, Decreased in situ expression of interleukin-10 receptor is correlated with the exacerbated inflammatory and cytotoxic responses observed in mucosal leishmaniasis, Infec. Immun., 73, 7853, 10.1128/IAI.73.12.7853-7859.2005

Ferreira, 2015, Mixed infection of Leishmania infantum and Leishmania braziliensis in rodents from endemic urban area of the New World, BMC Vet. Res., 11, 71, 10.1186/s12917-015-0392-y

Fox, 2000, Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy, Nat. Med., 6, 536, 10.1038/75015

Gomes-Silva, 2007, Can interferon-gamma and interleukin-10 balance be associated with severity of human Leishmania (Viannia) braziliensis infection?, Clin. Exp. Immunol., 149, 440, 10.1111/j.1365-2249.2007.03436.x

Goto, 2010, Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis, Exp. Rev. Anti Infect. Ther., 8, 419, 10.1586/eri.10.19

Green, 1990, Leishmania major amastigotes initiate the l-arginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha, J. Immunol., 145, 4290, 10.4049/jimmunol.145.12.4290

Greene, 1983, Nonspecific suppression of antigen-induced lymphocyte blastogenesis in Onchocerca volvulus infection in man, Clin. Exp. Immunol., 52, 259

Harnett, 2004, The anti-inflammatory potential of the filarial nematode secreted product, ES-62, Curr. Top. Med. Chem., 4, 553, 10.2174/1568026043451212

Hoffmann, 1934, The sedimentation concentration method in Schistosoma mansoni, Puerto Rico J. Public Health Trop. Med., 9, 283

Jirmanus, 2012, Epidemiological and clinical changes in American tegumentary leishmaniasis in an area of Leishmania (Viannia) braziliensis transmission over a 20-year period, Am. J. Trop. Med. Hyg., 86, 426, 10.4269/ajtmh.2012.11-0378

Katz, 1972, A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni, Rev. Inst. Med. Trop. São Paulo, 14, 397

Kirwan, 2010, Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial, BMC Infect. Dis., 10, 277, 10.1186/1471-2334-10-277

Leite, 2012, Ecto-nucleotidase activities of promastigotes from Leishmania (Viannia) braziliensis relates to parasite infectivity and disease clinical outcome, PLoS Negl. Trop. Dis., 6, e1850, 10.1371/journal.pntd.0001850

Liwski, 2000, Prolongation of allograft survival by Nippostrongylus brasiliensis is associated with decreased allospecific cytotoxic T lymphocyte activity and development of T cytotoxic cell type 2 cells, Transplantation, 69, 1912, 10.1097/00007890-200005150-00029

Massacand, 2009, Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function, Proc. Natl. Acad. Sci. U. S. A., 106, 13968, 10.1073/pnas.0906367106

Maizels, 2003, Immune regulation by helminth parasites: cellular and molecular mechanisms, Nat. Rev. Immunol., 3, 733, 10.1038/nri1183

Matos, 2005, Differential interferon-gamma production characterizes the cytokine responses to Leishmania and Mycobacterium leprae antigens in concomitant mucocutaneous leishmaniasis and lepromatous leprosy, Clin. Infect. Dis., 40, e5, 10.1086/427069

Mougneau, 2011, Cell biology and immunology of Leishmania, Immunol. Rev., 240, 286, 10.1111/j.1600-065X.2010.00983.x

Nacher, 2001, Helminth infections are associated with protection from malaria-related acute renal failure and jaundice in Thailand, Am. J. Trop. Med. Hyg., 65, 834, 10.4269/ajtmh.2001.65.834

Naderer, 2011, Intracellular growth and pathogenesis of Leishmania parasites, Essays Biochem, 51, 81, 10.1042/bse0510081

Neto, 2006, Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000–2006), Braz. J. Infect. Dis., 13, 427

Newlove, 2011, Antihelminthic therapy and antimony in cutaneous leishmaniasis: a randomized, double-blind, placebo-controlled trial in patients co-infected with helminths and Leishmania braziliensis, Am. J. Trop. Med. Hyg., 84, 551, 10.4269/ajtmh.2011.10-0423

Oliveira-Neto, 2000, Mucosal leishmaniasis (espundia) responsive to low dose of N-methyl glucamine (Glucantime) in Rio de Janeiro, Brazil, Rev. Inst. Med. Trop. Sao Paulo, 42, 321, 10.1590/S0036-46652000000600004

Oliveira-Neto, 1988, An outbreak of American cutaneous leishmaniasis (Leishmania braziliensis braziliensis) in a periurban area of Rio de Janeiro city, Brazil: clinical and epidemiological studies, Mem. Inst. Oswaldo Cruz, 83, 427, 10.1590/S0074-02761988000400006

Oliveira-Neto, 1997, A low-dose antimony treatment in 159 patients with American cutaneous leishmaniasis: extensive follow-up studies (up to 10 years), Am. J. Trop. Med. Hyg., 57, 651, 10.4269/ajtmh.1997.57.651

O'Neal, 2007, Influence of helminth infections on the clinical course of and immune response to Leishmania braziliensis cutaneous leishmaniasis, J. Infect. Dis., 195, 142, 10.1086/509808

Peters, 1990, Visceral leishmaniasis in HIV infection and AIDS: clinical features and response to therapy, Q. J. Med., 77, 1101, 10.1093/qjmed/77.2.1101

Peters, 1980, Quick Kato smear for field quantification of Schistosoma mansoni eggs, Am. J. Trop. Med. Hyg., 29, 217, 10.4269/ajtmh.1980.29.217

Pirmez, 1993, Cytokine patterns in the pathogenesis of human leishmaniasis, J. Clin. Invest., 91, 1390, 10.1172/JCI116341

Pulendran, 2012, New paradigms in type 2 immunity, Science, 337, 431, 10.1126/science.1221064

Rangel, 1990, Studies on sandfly fauna (Diptera: Psychodidae) in a foci of cutaneous leishmaniasis in Mesquita, Rio de Janeiro State, Brazil, Mem. Inst. Oswaldo Cruz, 85, 39, 10.1590/S0074-02761990000100006

Rocha, 2007, Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice, Infect. Immun., 75, 3823, 10.1128/IAI.01335-06

Rocha, 1971, Prolonged Salmonella bacteremia in patients with Schistosoma mansoni infection, Arch. Intern. Med., 128, 254, 10.1001/archinte.1971.00310200090009

Locksley, 1987, Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T-cell subsets, Ann. Inst. Pasteur Immunol., 138, 744, 10.1016/S0769-2625(87)80030-2

Rogers, 2004, The human cytokine response to Leishmania major early after exposure to the parasite in vitro, J. Parasitol., 90, 557, 10.1645/GE-3317

Sabin, 1996, Impairment of tetanus toxoid-specific TH1-like immune responses in humans infected with Schistosoma mansoni, J. Infect. Dis., 173, 269, 10.1093/infdis/173.1.269

Sacks, 2004, Re-examination of the immunosuppressive mechanisms mediating non-cure of Leishmania infection in mice, Immunol. Rev., 201, 225, 10.1111/j.0105-2896.2004.00185.x

Schubach, 2005, Retrospective study of 151 patients with cutaneous leishmaniasis treated with meglumine antimoniate, Rev. Soc. Bras. Med. Trop., 38, 213, 10.1590/S0037-86822005000300001

Silveira, 2009, Immunopathogenic competences of Leishmania (V.) braziliensis and L. (L.) amazonensis in American cutaneous leishmaniasis, Parasite Immunol., 31, 423, 10.1111/j.1365-3024.2009.01116.x

Soong, 2012, Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis, Semin. Immunopathol., 34, 735, 10.1007/s00281-012-0350-8

Soulsby, 1987, The evasion of the immune response and immunological unresponsiveness: parasitic helminth infections, Immunol. Lett., 16, 315, 10.1016/0165-2478(87)90164-7

Souza, 2012, American tegumentary leishmaniasis: cytokines and nitric oxide in active disease and after clinical cure, with or without chemotherapy, Scand. J. Immunol., 76, 175, 10.1111/j.1365-3083.2012.02717.x

Souza, 1992, Montenegro skin tests for American cutaneous leishmaniasis carried out on school children in Rio de Janeiro, Brazil: an indicator of transmission risk, Acta Trop., 52, 111, 10.1016/0001-706X(92)90026-T

Su, 2006, Reduced protective efficacy of a blood-stage malaria vaccine by concurrent nematode infection, Infect. Immun., 2006, 2138, 10.1128/IAI.74.4.2138-2144.2006

Taylor, 2012, T cells in helminth infection: the regulators and the regulated, Trends Immunol., 33, 181, 10.1016/j.it.2012.01.001

Tuon, 2008, Local immunological factors associated with recurrence of mucosal leishmaniasis, Clin. Immunol., 128, 442, 10.1016/j.clim.2008.05.007

van den Bogaart, 2013, Concomitant malaria among visceral leishmaniasis in-patients from Gedarif and Sennar States, Sudan: a retrospective case-control study, BMC Public Health, 13, 332, 10.1186/1471-2458-13-332

van den Bogaart, 2014, Cytokine profiles amongst Sudanese patients with visceral leishmaniasis and malaria co-infections, BMC Immunol., 15, 16, 10.1186/1471-2172-15-16

Vieira-Gonçalves, 2008, Clinical features of cutaneous and disseminated cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis in Paraty, Rio de Janeiro, Int. J. Dermatol., 47, 926, 10.1111/j.1365-4632.2008.03701.x

Wilson, 2004, Regulation of allergy and autoimmunity in helminth infection, Clin. Rev. Allergy Immunol., 26, 35, 10.1385/CRIAI:26:1:35