Interplay of vitamin D and metabolic syndrome: A review
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Bouillon, 2008, Vitamin D and human health: lessons from vitamin D receptor null mice, Endocr Rev, 29, 726, 10.1210/er.2008-0004
Mithal, 2009, Global vitamin D status and determinants of hypovitaminosis D, Osteoporos Int, 20, 1807, 10.1007/s00198-009-0954-6
ATP III, 2009
Pitsavos, 2006, Diet, exercise and the metabolic syndrome, Rev Diabetes Stud, 3, 118, 10.1900/RDS.2006.3.118
Li, 2004, Vitamin D: a negative endocrine regulator of the renin–angiotensin system and blood pressure, J Steroid Biochem Mol Biol, 89–90, 387, 10.1016/j.jsbmb.2004.03.004
Zhou, 2006, Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia, J Clin Invest, 116, 1703, 10.1172/JCI27793
Wikvall, 2001, Cytochrome P450 enzymes in the bioactivation of vitamin D to its hormonal form: review, Int J Mol Med, 7, 201
Helvig, 2010, Dysregulation of renal vitamin D metabolism in the uremic rat, Kidney Int, 78, 463, 10.1038/ki.2010.168
Holick, 2009, Vitamin D status: measurement, interpretation, and clinical application, Ann Epidemiol, 19, 73, 10.1016/j.annepidem.2007.12.001
Holick, 2008, Vitamin D deficiency: a worldwide problem with health consequences, Am J Clin Nutr, 87, 1080, 10.1093/ajcn/87.4.1080S
Duprez, 1994, Relationship between vitamin D3 and the peripheral circulation in moderate arterial primary hypertension, Blood Press, 3, 389, 10.3109/08037059409102292
Kunutsor, 2013, Vitamin D and risk of future hypertension: meta-analysis of 283,537 participants, Eur J Epidemiol, 28, 205, 10.1007/s10654-013-9790-2
Scragg, 2007, Serum 25-hydroxyvitamin D, ethnicity, and blood pressure in the Third National Health and Nutrition Examination Survey, Am J Hypertens, 20, 713, 10.1016/j.amjhyper.2007.01.017
Forman, 2007, Plasma 25-hydroxyvitamin D levels and risk of incident hypertension, Hypertension, 49, 1063, 10.1161/HYPERTENSIONAHA.107.087288
Forman, 2008, Plasma 25-hydroxyvitamin D levels and risk of incident hypertension among young women, Hypertension, 52, 828, 10.1161/HYPERTENSIONAHA.108.117630
Hypponen, 2008, 25-Hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort, Diabetes, 57, 298, 10.2337/db07-1122
Mheid, 2011, Vitamin D status is associated with arterial stiffness and vascular dysfunction in healthy humans, J Am Coll Cardiol, 58, 186, 10.1016/j.jacc.2011.02.051
Snijder, 2007, Vitamin D status and parathyroid hormone levels in relation to blood pressure: a population-based study in older men and women, J Intern Med, 261, 558, 10.1111/j.1365-2796.2007.01778.x
Forman, 2010, Plasma 25-hydroxyvitamin D and regulation of the renin–angiotensin system in humans, Hypertension, 55, 1283, 10.1161/HYPERTENSIONAHA.109.148619
Tomaschitz, 2010, Independent association between 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and the renin–angiotensin system: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study, Clin Chim Acta, 411, 1354, 10.1016/j.cca.2010.05.037
Kota, 2011, Renin–angiotensin system activity in vitamin D deficient, obese individuals with hypertension: an urban Indian study, Indian J Endocr Metab, 15, 395, 10.4103/2230-8210.86985
Forman, 2013, Effect of vitamin D supplementation on blood pressure in blacks, Hypertension, 61, 779, 10.1161/HYPERTENSIONAHA.111.00659
Goel, 2011, Role of vitamin D supplementation in hypertension, Indian J Clin Biochem, 26, 88, 10.1007/s12291-010-0092-0
Wu, 2010, Effects of vitamin D supplementation on blood pressure, South Med J, 103, 729, 10.1097/SMJ.0b013e3181e6d389
Pfeifer, 2001, Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women, J Clin Endocrinol Metab, 86, 1633
Weng, 2013, Vitamin D deficiency induces high blood pressure and accelerates atherosclerosis in mice, PLOS ONE, 8, 1, 10.1371/journal.pone.0054625
Carrara, 2012, Cholecalciferol administration blunts the systemic renin–angiotensin system in essential hypertensives with hypovitaminosis D, J Renin Angiotensin Aldosterone Syst, 0, 1
Scragg, 2005, Serum 25-hydroxycholecalciferol concentration in newly detected hypertension, Am J Hypertens, 8, 429, 10.1016/0895-7061(94)00195-H
Earthman, 2012, The link between obesity and low 25-hydroxyvitamin D concentrations: considerations and implications, Int J Obes (Lond), 36, 387, 10.1038/ijo.2011.119
Vimaleswaran, 2013, Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts, PLoS Med, 10, e1001383, 10.1371/journal.pmed.1001383
Cheng, 2010, Adiposity, cardiometabolic risk, and vitamin d status: the Framingham heart study, Diabetes, 59, 242, 10.2337/db09-1011
Aasheim, 2008, Vitamin status in morbidly obese patients: a cross-sectional study, Am J Clin Nutr, 87, 362, 10.1093/ajcn/87.2.362
Grineva, 2013, Vitamin D deficiency is a risk factor for obesity and diabetes type 2 in women at late reproductive age, Aging, 5, 575, 10.18632/aging.100582
Carretero, 2007, Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity, Clin Nutr, 26, 573, 10.1016/j.clnu.2007.05.009
Kamycheva, 2004, Serum parathyroid hormone level is associated with body mass index. The 5th Tromso study, Eur J Endocrinol, 151, 167, 10.1530/eje.0.1510167
Wortsman, 2000, Decreased bioavailability of vitamin D in obesity, Am J Clin Nutr, 72, 690, 10.1093/ajcn/72.3.690
Florez, 2007, Outdoor exercise reduces the risk of hypovitaminosis D in the obese, J Steroid Biochem Mol Biol, 103, 679, 10.1016/j.jsbmb.2006.12.032
Kull, 2009, Body mass index determines sunbathing habits: implications on vitamin D levels, Intern Med J, 39, 256, 10.1111/j.1445-5994.2009.01900.x
Aarts, 2011, Vitamin D absorption: consequences of gastric bypass surgery, Eur J Endocrinol, 164, 827, 10.1530/EJE-10-1126
Shapses, 2012, Hormonal and dietary influences on true fractional calcium absorption in women: role of obesity, Osteoporos Int, 23, 2607, 10.1007/s00198-012-1901-5
Guasch, 2012, Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study, Cardiovasc Diabetol, 11, 149, 10.1186/1475-2840-11-149
Salehpour, 2012, A 12-week double-blind randomized clinical trial of vitamin D3 supplementation on body fat mass in healthy overweight and obese women, Nutr J, 11, 78, 10.1186/1475-2891-11-78
Carrillo, 2013, Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and obese adults, Clin Nutr, 32, 375, 10.1016/j.clnu.2012.08.014
Hey, 1982, Vitamin D deficiency in obese patients and changes in circulating vitamin D metabolites following jejunoileal bypass, Int J Obes, 6, 473
Rosenblum, 2011, Calcium and vitamin D supplementation is associated with decreased abdominal visceral adipose tissue in overweight and obese adults, Am J Clin Nutr, 95, 101, 10.3945/ajcn.111.019489
Liu, 2009, Plasma 25-hydroxyvitamin D is associated with markers of the insulin resistant phenotype in nondiabetic adults, J Nutr, 139, 329, 10.3945/jn.108.093831
Weishaar, 1987, Involvement of vitamin D3 with cardiovascular function and its direct and indirect effects, Am J Physiol Endocrinol Metab, 253, 675, 10.1152/ajpendo.1987.253.6.E675
Norman, 1980, Vitamin D deficiency inhibits pancreatic secretion of insulin, Science, 209, 823, 10.1126/science.6250216
Pittas, 2007, The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in nondiabetic adults, Diabetes Care, 30, 980, 10.2337/dc06-1994
Tsur, 2013, Decreased serum concentrations of 25-hydroxycholecalciferol are associated with increased risk of progression to impaired fasting glucose and diabetes, Diabetes Care, 36, 51361, 10.2337/dc12-1050
Forouhi, 2008, Baseline serum 25-hydroxy vitamin D is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990–2000, Diabetes, 57, 2619, 10.2337/db08-0593
Chiu, 2004, Hypovitaminosis D is associated with insulin resistance and β cell dysfunction, Am J Clin Nutr, 79, 820, 10.1093/ajcn/79.5.820
Seo, 2013, Low vitamin D status is associated with nonalcoholic fatty liver disease independent of visceral obesity in Korean adults, PLOS ONE, 8, 1, 10.1371/journal.pone.0075197
Dutta, 2013, Serum vitamin-D predicts insulin resistance in individuals with prediabetes, Indian J Med Res, 138, 853
Mitri, 2011, Vitamin D and type 2 diabetes: a systematic review, Eur J Clin Nutr, 65, 1005, 10.1038/ejcn.2011.118
Grimnes, 2011, Vitamin D, insulin secretion, sensitivity, and lipids: results from a case–control study and a randomized controlled trial using hyperglycemic clamp technique, Diabetes, 60, 2748, 10.2337/db11-0650
George, 2012, Effect of vitamin D supplementation on glycaemic control and insulin resistance: a systematic review and meta-analysis, Diabetes Med, 29, 142, 10.1111/j.1464-5491.2012.03672.x
Davidson, 2013, High-dose vitamin D supplementation in people with prediabetes and hypovitaminosis D, Diabetes Care, 36, 260, 10.2337/dc12-1204
Harris, 2012, A randomized, placebo-controlled trial of vitamin D supplementation to improve glycaemia in overweight and obese African Americans, Diabetes Obes Metab, 14, 789, 10.1111/j.1463-1326.2012.01605.x
Hurst, 2010, Vitamin D supplementation reduces insulin resistance in South Asian women in New Zealand who are insulin resistant and vitamin D deficient: a randomised placebo controlled trial, Br J Nutr, 103, 549, 10.1017/S0007114509992017
Giulietti, 2004, Vitamin D deficiency in early life accelerates type 1 diabetes in non-obese diabetic mice, Diabetologia, 47, 451, 10.1007/s00125-004-1329-3
Hypponen, 2001, Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study, Lancet, 358, 1500, 10.1016/S0140-6736(01)06580-1
Talaei, 2013, The effect of vitamin D on insulin resistance in patients with type 2 diabetes, Diabetol Metab Syndr, 5, 8, 10.1186/1758-5996-5-8
Jorde, 2011, Vitamin D and metabolic health with special reference to the effect of vitamin D on serum lipids, Prog Lipid Res, 50, 303, 10.1016/j.plipres.2011.05.001
Jaimungal, 2011, The emerging evidence for vitamin D-mediated regulation of apolipoprotein AI synthesis, Nutr Res, 31, 805, 10.1016/j.nutres.2011.09.005
Skaaby, 2012, Vitamin D status and changes in cardiovascular risk factors: a prospective study of a general population, Cardiology, 123, 62, 10.1159/000341277
Minambres, 2014, Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment, Diabetol Metab Syndr, 6, 7, 10.1186/1758-5996-6-7
Ford, 2005, Concentrations of serum vitamin D and the metabolic syndrome among U.S. adults, Diabetes Care, 2, 1128
Shenoy, 2014, Association between vitamin D, fasting blood glucose, HbA1c and fasting lipid profile in euglycemic individuals, J Res Diabetes, 10.5171/2014.929743
Chaudhuri, 2013, Deficiency of 25-hydroxyvitamin d and dyslipidemia in Indian subjects, J Lipids, 2013, 1, 10.1155/2013/623420
Lu, 2009, Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals, Diabetes Care, 32, 1278, 10.2337/dc09-0209
Baker, 2012, Vitamin D, metabolic dyslipidemia, and metabolic syndrome in rheumatoid arthritis, Am J Nutr, 125, 1036e9
Karhapaa, 2010, Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias, J Intern Med, 268, 604, 10.1111/j.1365-2796.2010.02279.x
Shivaprakash, 2014, Relationships between serum 25-hydroxy vitamin D levels and plasma glucose and lipid levels in pediatric patients in a rural hospital, Int J Sci Study, 1, 24
Gupta, 2014, Vitamin D status and risk of ischemic stroke in North Indian patients, Indian J Endocr Metab, 18, 721, 10.4103/2230-8210.139241
George, 2013, The association of 25 hydroxyvitamin D and parathyroid hormone with metabolic syndrome in two ethnic groups in South Africa, PLOS ONE, 8, 1, 10.1371/journal.pone.0061282
Chai, 2013, Effects of calcium and vitamin D supplementation on blood pressure and serum lipids and carotenoids: a randomized, double-blind, placebo-controlled, clinical trial, Ann Epidemiol, 23, 564, 10.1016/j.annepidem.2013.07.003
Khajehdehi, 2003, Effect of oral calcitriol pulse therapy on the lipid, calcium, and glucose homeostasis of hemodialysis-patients: its safety in a combination with oral calcium carbonate, J Renal Nutr, 13, 78, 10.1053/jren.2003.50026
Major, 2007, Supplementation with calcium+vitamin D enhances the beneficial effect of weight loss on plasma lipid and lipoprotein concentrations, Am J Clin Nutr, 85, 54
Wang, 2012, Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials, Lipids Health Dis, 11, 42, 10.1186/1476-511X-11-42
Ponda, 2012, The short-term effects of vitamin D repletion on cholesterol: a randomized, placebo-controlled trial, Arterioscler Thromb Vasc Biol, 32, 2510, 10.1161/ATVBAHA.112.254110
Maki, 2011, Effects of vitamin D supplementation on 25-hydroxyvitamin D, high-density lipoprotein cholesterol, and other cardiovascular disease risk markers in subjects with elevated waist circumference, Int J Food Sci Nutr, 62, 318, 10.3109/09637486.2010.536146
Heikkinen, 1997, Long-term vitamin D3 supplementation may have adverse effects on serum lipids during postmenopausal hormone replacement therapy, Eur J Endocrinol, 137, 495, 10.1530/eje.0.1370495
Scragg, 1981, Seasonality of cardiovascular disease mortality and the possible protective effect of ultra-violet radiation, Int J Epidemiol, 10, 337, 10.1093/ije/10.4.337
Zittermann, 2012, Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies, Am J Clin Nutr, 95, 91, 10.3945/ajcn.111.014779
Duranton, 2013, Vitamin D treatment and mortality in chronic kidney disease: a systematic review and meta-analysis, Am J Nephrol, 37, 239, 10.1159/000346846
Bittner, 2012, Vitamin D levels do not predict cardiovascular events in statin-treated patients with stable coronary disease, Am Heart J, 164, 387, 10.1016/j.ahj.2012.06.016
Schottker, 2012, Serum 25-hydroxyvitamin D levels and overall mortality. A systematic review and meta-analysis of prospective cohort studies, Ageing Res Rev, 12, 708, 10.1016/j.arr.2012.02.004
Pilz, 2008, Low vitamin D levels predict stroke in patients referred to coronary angiography, Stroke, 39, 2611, 10.1161/STROKEAHA.107.513655
Dobnig, 2008, Independent association of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality, Arch Intern Med, 168, 1340, 10.1001/archinte.168.12.1340
Joergensen, 2012, Vitamin D levels and asymptomatic coronary artery disease in type 2 diabetic patients with elevated urinary albumin excretion rate, Diabetes Care, 35, 168, 10.2337/dc11-1372
Rajasree, 2001, Serum 25-hydroxyvitamin D3 levels are elevated in South Indian patients with ischemic heart disease, Eur J Epidemiol, 17, 567, 10.1023/A:1014559600042
Chowdhury, 2012, Circulating vitamin D, calcium and risk of cerebrovascular disease: a systematic review and meta-analysis, Eur J Epidemiol, 27, 581, 10.1007/s10654-012-9729-z
Sun, 2012, 25-Hydroxyvitamin D levels and the risk of stroke: a prospective study and meta-analysis, Stroke, 43, 1470, 10.1161/STROKEAHA.111.636910
Anderson, 2010, Relation of vitamin D deficiency to cardiovascular risk factors, disease status, and incident events in a general healthcare population, Am J Cardiol, 106, 963, 10.1016/j.amjcard.2010.05.027
Pilz, 2008, Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography, J Clin Endocrinol Metab, 93, 3927, 10.1210/jc.2008-0784
Drechsler, 2010, Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients, Eur Heart J, 31, 2253, 10.1093/eurheartj/ehq246
Carrelli, 2011, Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan Study, Stroke, 42, 2240, 10.1161/STROKEAHA.110.608539
Wang, 2008, Vitamin D deficiency and risk of cardiovascular disease, Circulation, 117, 503, 10.1161/CIRCULATIONAHA.107.706127
Giovannucci, 2008, 25-Hydroxyvitamin D and risk of myocardial infarction in men: a prospective study, Arch Intern Med, 168, 174, 10.1001/archinte.168.11.1174
Kilkkinen, 2009, Vitamin D status and the risk of cardiovascular disease death, Am J Epidemiol, 170, 1032, 10.1093/aje/kwp227
Fiscella, 2010, Vitamin D, race, and cardiovascular mortality: findings from a national US sample, Ann Fam Med, 8, 11, 10.1370/afm.1035
Semba, 2010, Relationship of 25-hydroxyvitamin D with all-cause and cardiovascular disease mortality in older community-dwelling adults, Eur J Clin Nutr, 64, 203, 10.1038/ejcn.2009.140
Bolland, 2010, Vitamin D insufficiency and health outcomes over 5 year in older women, Am J Clin Nutr, 91, 82, 10.3945/ajcn.2009.28424
Parker, 2010, Levels of vitamin D and cardiometabolic disorders: systematic review and meta-analysis, Maturitas, 65, 225, 10.1016/j.maturitas.2009.12.013
Grandi, 2010, Vitamin D and cardiovascular disease: systematic review and meta-analysis of prospective studies, Prev Med, 51, 228, 10.1016/j.ypmed.2010.06.013
Parikh, 2012, Circulating 25-hydroxyvitamin D concentrations are correlated with cardiometabolic risk among American black and white adolescents living in a year-round sunny climate, Diabetes Care, 35, 1133, 10.2337/dc11-1944
Kuloglu, 2013, Serum 25-hydroxyvitamin D level is associated with aortic distensibility and left ventricle hypertrophy in newly diagnosed type 2 diabetes mellitus, Diabetes Vasc Dis Res, 10, 546, 10.1177/1479164113491125
Williams, 2014, Associations of childhood 25-hydroxyvitamin D2 and D3 and cardiovascular risk factors in adolescence: prospective findings from the Avon Longitudinal Study of Parents and Children, Eur J Prev Cardiol, 21, 3281, 10.1177/2047487312465688
Wilke, 2009, Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension, Pharmacogenomics, 10, 1789, 10.2217/pgs.09.101
Shen, 2010, Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification, Arterioscler Thromb Vasc Biol, 30, 2648, 10.1161/ATVBAHA.110.211805
Zittermann, 2006, Vitamin D insufficiency in congestive heart failure: why and what to do about it?, Heart Fail Rev, 11, 25, 10.1007/s10741-006-9190-8
Brewer, 2011, Vitamin D in atherosclerosis, vascular disease, and endothelial function, Curr Drug Targets, 12, 54, 10.2174/138945011793591617
Xiang, 2005, Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin–angiotensin systems, Am J Physiol Endocrinol Metab, 288, 125, 10.1152/ajpendo.00224.2004
Zhou, 2008, Calcium-independent and 1,25(OH2)D3-dependent regulation of the renin–angiotensin system in 1a-hydroxylase knockout mice, Kidney Int, 74, 170, 10.1038/ki.2008.101
Pilz, 2010, Vitamin D deficiency and myocardial diseases, Mol Nutr Food Res, 54, 1103, 10.1002/mnfr.200900474
Chen, 2008, Expression of the vitamin D receptor is increased in the hypertrophic heart, Hypertension, 52, 1106, 10.1161/HYPERTENSIONAHA.108.119602
Green, 2006, Calcitriol modulation of cardiac contractile performance via protein kinase C, J Mol Cell Cardiol, 41, 350, 10.1016/j.yjmcc.2006.05.019
Timms, 2002, Circulating MMP9, vitamin D and variation in the TIMP-1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders?, QJM, 95, 787, 10.1093/qjmed/95.12.787
Molinari, 2011, 1α,25-Dihydroxycholecalciferol induces nitric oxide production in cultured endothelial cells, Cell Physiol Biochem, 27, 661, 10.1159/000330075
Tare, 2011, Vitamin D insufficiency is associated with impaired vascular endothelial and smooth muscle function and hypertension in young rats, J Physiol (Lond), 589, 4777, 10.1113/jphysiol.2011.214726
Oh, 2009, 1,25(OH)2 vitamin D inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus, Circulation, 120, 687, 10.1161/CIRCULATIONAHA.109.856070
Pilz, 2011, Vitamin D, cardiovascular disease and mortality, Clin Endocrinol (Oxf), 75, 575, 10.1111/j.1365-2265.2011.04147.x
Martinesi, 2006, 1,25-Dihydroxyvitamin D3 inhibits tumor necrosis factor-alpha-induced adhesion molecule expression in endothelial cells, Cell Biol Int, 30, 365, 10.1016/j.cellbi.2006.01.004
Husain, 2009, Combination therapy with paricalcitol and enalapril ameliorates cardiac oxidative injury in uremic rats, Am J Nephrol, 29, 465, 10.1159/000178251
Li, 2011, Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin, Arterioscler Thromb Vasc Biol, 30, 321, 10.1161/ATVBAHA.109.196576
Manson, 2010, Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health Initiative, Menopause, 17, 683, 10.1097/gme.0b013e3181d683b5
Canning, 2001, 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) hampers the maturation of fully active immature dendritic cells from monocytes, Eur J Endocrinol, 145, 351, 10.1530/eje.0.1450351
Zhu, 2005, Calcium and 1-alpha,25-dihydroxyvitamin D3 target the TNF-alpha pathway to suppress experimental inflammatory bowel disease, Eur J Immunol, 35, 217, 10.1002/eji.200425491
Bjelakovic, 2011, Vitamin D supplementation for prevention of mortality in adults, Cochrane Database Syst Rev, 7, 10.1002/14651858.CD007470.pub2
Schleithoff, 2006, Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial, Am J Clin Nutr, 83, 754, 10.1093/ajcn/83.4.754
Bolland, 2011, Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis, BMJ, 342, 2040, 10.1136/bmj.d2040
Rajpathak, 2010, Effect of 5 y of calcium plus vitamin D supplementation on change in circulating lipids: results from the Women's Health Initiative, Am J Clin Nutr, 91, 894, 10.3945/ajcn.2009.28579
Sun, 2011, Vitamin D intake and risk of cardiovascular disease in US men and women, Am J Clin Nutr, 94, 534, 10.3945/ajcn.110.008763