Interactions of pentamethylenetetrazole and tetrazole analogues with the picrotoxinin site of the benzodiazepine-gaba receptor-ionophore complex

European Journal of Pharmacology - Tập 98 Số 3-4 - Trang 337-345 - 1984
R. Ramanjaneyulu1, Maharaj K. Ticku1
1Division of Molecular Pharmacology, Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78284, U.S.A.

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Bowery, 1974, Depolarizing actions of γ-aminobutyric acid and related compounds on superior cervical ganglia in vitro, Br. J. Pharmacol., 50, 205, 10.1111/j.1476-5381.1974.tb08563.x

Bowery, 1976, Bicyclophophosphorus esters that are potent convulsants and GABA antagonists, Nature, 261, 601, 10.1038/261601a0

Gross, 1946, Studies with tetrazole derivatives I, J. Pharmacol. Exp. Ther., 87, 291

Gross, 1984, Studies with tetrazole derivatives II, J. Pharmacol. Exp. Ther., 87, 299

Harrison, 1983, The picrotoxin-like action of a convulsant benzodiazepine R05-3663, European J. Pharmacol., 87, 155, 10.1016/0014-2999(83)90064-X

Hill, 1974, Convulsant drugs and central inhibitory processes

Leeb-Lundberg, 1981, Dihydropicrotoxinin binding sites in mammalian brain: Interactions with convulsant and depressant benzodiazepines, Brain Res., 316, 399, 10.1016/0006-8993(81)90141-4

Leeb-Lundberg, 1980, Barbiturate receptors are coupled to benzodiazepine receptors, 77, 7468

Lowry, 1951, Protein measurement with the folin phenol reagents, J. Biol. Chem., 193, 265, 10.1016/S0021-9258(19)52451-6

Macdonald, 1977, Pentylenetetrazole and penicilin are selective antagonists of GABA-mediated postsynaptic inhibition in cultured mammalian neurons, Nature, 267, 720, 10.1038/267720a0

Marangos, 1979, Purinergic inhibition of diazepam binding to rat brain in vitro, Life Sci., 24, 851, 10.1016/0024-3205(79)90369-2

Muller, 1978, Benzodiazepine receptor binding: The interaction of some nonbenzodiazepine drugs with specific [3H]diazepam binding to rat brain synaptosomal membranes, Naunyn-Schmiedeb. Arch. Pharmacol., 305, 23, 10.1007/BF00497002

Olsen, 1981, GABA-benzodiazepine-barbiturate receptor interactions, J. Neurochem., 37, 1, 10.1111/j.1471-4159.1981.tb05284.x

Olsen, 1979, GABA receptors and ionophore binding sites: Interactions with various drugs, 165

Pellmar, 1977, Synaptic mechanism of pentylenetetrazole sensitivity for chloride conductance, Science, 197, 912, 10.1126/science.887932

Ramanjaneyulu, 1984, Binding characteristics and interactions of depressant drugs with [35S]-t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site, J. Neurochem., 42, 221, 10.1111/j.1471-4159.1984.tb09721.x

Rehavi, 1982, Effects of tetrazole derivatives on [3H]diazepam binding in vitro: Correlation with convulsant potency, European J. Pharmacol., 78, 353, 10.1016/0014-2999(82)90037-1

Schlosser, 1979, Reduction of gamma-aminobutyric acid (GABA)-mediated transmission by a convulsant benzodiazepine, J. Pharmacol. Exp. Ther., 211, 290

Scholfield, 1980, Convulsants antagonize inhibition in the olfactory cortex slice, Naunyn-Schmiedeb. Arch. Pharmacol., 314, 29, 10.1007/BF00498428

Simmonds, 1978, Presynaptic actions of γ-aminobutyric acid and some antagonists in a slice preparation of cuneate nucleus, Br. J. Pharmacol., 63, 495, 10.1111/j.1476-5381.1978.tb07803.x

Simmonds, 1980, Evidence that bicuculline and pricotoxin act at separate sites to antagonize γ-aminobutyric acid in rat cuneate nucleus, Neuropharmacol., 19, 39, 10.1016/0028-3908(80)90164-1

Simmonds, 1982, Classification of some GABA antagonists with regard to site of action and potency in slices of rat cuneate nucleus, European J. Pharmacol., 80, 347, 10.1016/0014-2999(82)90080-2

Squires, 1983, [35S]-t-Butylbicyclophosphothionate binds with high affinity to brain specific sites coupled to γ-aminobutyric acid-A and ion recognition sites, Mol. Pharmacol., 23, 326

Stone, 1970, Convulsant actions of tetrazole derivatives, Pharmacol., 3, 367, 10.1159/000136093

Supavilai, 1982, Anion-dependent modulation of [3H]muscimol binding of GABA-stimulated [3H]flunitrazepam binding by picrotoxin and related CNS convulsants, European J. Pharmacol., 81, 687, 10.1016/0014-2999(82)90362-4

Takeuchi, 1969, A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish, J. Physiol., 205, 377, 10.1113/jphysiol.1969.sp008972

Tallman, 1980, Receptors for the age of anxiety: Pharmacology of the benzodiazepines, Science, 207, 274, 10.1126/science.6101294

Ticku, 1981, Interaction of depressant, convulsant and anticonvulsant barbiturates with [3H]diazepam binding site at the benzodiazepine-GABA receptor-ionophore complex, Biochem. Pharmacol., 30, 1573, 10.1016/0006-2952(81)90383-X

Ticku, 1978, Binding of [3H]-α-dihydropicrotoxinin, a gamm-aminobutyric acid synaptic antagonist, to rat brain membranes, Mol. Pharmacol., 14, 391

Ticku, 1978, Interaction of barbiturates with dihydropicrotoxinin binding sites possibly related to gamma-aminobutyric acid receptor-ionophores, Life Sci., 22, 1643, 10.1016/0024-3205(78)90061-9

Ticku, 1979, Cage convulsants inhibit picrotoxinin binding, Neuropharmacology, 18, 315, 10.1016/0028-3908(79)90132-1

Ticku, 1984, Picrotoxinin binding sites in brain

Ticku, 1984, Allosteric modulation of benzodiazepine-GABA receptor-ionophore complex by depressant and convulsant drugs

Yonekawa, 1980, Brain and plasma levels in mice of various 1,5-cyclopoly-methylenetetrazole1,5-CPMTZ) at convulsant doses, Pharmacologist, 22, 224

Woodbury, 1980, Convulsant drugs: Mechanisms of action, 249