Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): Anti-inflammatory and anti-cancer properties

International Immunopharmacology - Tập 12 Số 2 - Trang 368-377 - 2012
Anlys Olivera1, Terry W. Moore2,3, Fang Hu1, Andy Brown2, Aiming Sun2,3,4, Dennis C. Liotta2,3,4, James P. Snyder2,3, Younghyoun Yoon5,4, Hyunsuk Shim5,4, Adam I. Marcus6,4, Andrew H. Miller1,4, Thaddeus W. W. Pace1,4
1Department of Psychiatry and Behavioral Sciences, Emory University, 1365-B Clifton Road, Atlanta, GA 30322, USA
2Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, GA 30322, USA
3Emory Institute for Drug Discovery, Emory University, 1521 Dickey Drive, Atlanta, GA 30322, USA
4Winship Cancer Institute, Emory University, 1701 Uppergate Drive, Atlanta, GA 30322, USA
5Department of Radiology, Emory University, 1701 Uppergate Drive, Atlanta, GA 30322, USA
6Department of Hematology and Oncology, Emory University, 1701 Uppergate Drive, Atlanta, GA 30322, USA

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