Influences on Attitudes Regarding Potential COVID-19 Vaccination in the United States

Vaccines - Tập 8 Số 4 - Trang 582
Kendall Pogue1, Jamie L. Jensen2, Carter Stancil1, Daniel Ferguson2, Savannah J. Hughes1, Emily J. Mello1, Ryan Burgess1, Bradford K. Berges1, Abraham Quaye1, Brian D. Poole1
1Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA
2Department of Biology, Brigham Young University, Provo, UT 84602, USA

Tóm tắt

The COVID-19 pandemic continues to ravage the world, with the United States being highly affected. A vaccine provides the best hope for a permanent solution to controlling the pandemic. However, to be effective, a vaccine must be accepted and used by a large majority of the population. The aim of this study was to understand the attitudes towards and obstacles facing vaccination with a potential COVID-19 vaccine. To measure these attitudes a survey was administered to 316 respondents across the United States by a survey corporation. Structural equation modeling was used to analyze the relationships of several factors with attitudes toward potential COVID-19 vaccination. Prior vaccine usage and attitudes predicted attitudes towards COVID-19 vaccination. Assessment of the severity of COVID-19 for the United States was also predictive. Approximately 68% of all respondents were supportive of being vaccinated for COVID-19, but side effects, efficacy and length of testing remained concerns. Longer testing, increased efficacy and development in the United States were significantly associated with increased vaccine acceptance. Messages promoting COVID-19 vaccination should seek to alleviate the concerns of those who are already vaccine-hesitant. Messaging directed at the benefits of vaccination for the United States as a country would address the second predictive factor. Enough time should be taken to allay concerns about both short- and long-term side effects before a vaccine is released.

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Tài liệu tham khảo

Sharpe, H.R., Gilbride, C., Allen, E., Belij-Rammerstorfer, S., Bissett, C., Ewer, K., and Lambe, T. (2020). The early landscape of COVID-19 vaccine development in the UK and rest of the world. Immunology.

Wilner, M. (2020, September 02). ‘Urgent’ Request Sent to States in Push for Coronavirus Vaccine Delivery by Nov. 1. Available online: https://www.tampabay.com/florida-politics/buzz/2020/09/02/urgent-request-sent-to-states-in-push-for-coronavirus-vaccine-delivery-by-nov-1/.

The Associated Press (2020, July 05). Expectations for a COVID-19 Vaccine. Available online: http://www.apnorc.org/projects/Pages/Expectations-for-a-COVID-19-Vaccine.aspx.

Washington Post-ABC (2020, July 05). May 25–28, 2020 Washington Post-ABC News Poll. Available online: https://www.washingtonpost.com/context/may-25-28-2020-washington-post-abc-news-poll/bb30c35e-797e-4b5c-91fc-1a1cdfbe85cc/?itid=lk_inline_manual_2&itid=lk_inline_manual_2&itid=lk_inline_manual_2.

Kwok, 2020, Herd immunity—Estimating the level required to halt the COVID-19 epidemics in affected countries, J. Infect., 80, e32, 10.1016/j.jinf.2020.03.027

Palamenghi, 2020, Mistrust in biomedical research and vaccine hesitancy: The forefront challenge in the battle against COVID-19 in Italy, Eur. J. Epidemiol., 35, 785, 10.1007/s10654-020-00675-8

Sun, S., Lin, D., and Operario, D. (2020). Interest in COVID-19 vaccine trials participation among young adults in China: Willingness, reasons for hesitancy, and demographic and psychosocial determinants. medRxiv.

French, J., Deshpande, S., Evans, W., and Obregon, R. (2020). Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion Strategy. Int. J. Environ. Res. Public Health, 17.

Butler, 2015, Diagnosing the determinants of vaccine hesitancy in specific subgroups: The Guide to Tailoring Immunization Programmes (TIP), Vaccine, 33, 4176, 10.1016/j.vaccine.2015.04.038

Bish, 2010, Demographic and attitudinal determinants of protective behaviours during a pandemic: A review, Br. J. Health Psychol., 15, 797, 10.1348/135910710X485826

Bish, 2011, Factors associated with uptake of vaccination against pandemic influenza: A systematic review, Vaccine, 29, 6472, 10.1016/j.vaccine.2011.06.107

Agrawal, 2020, Vaccine Hesitancy as a Challenge or Vaccine Confidence as an Opportunity for Childhood Immunisation in India, Infect. Dis. Ther., 9, 421, 10.1007/s40121-020-00302-9

Johnson, D.K., Mello, E.J., Walker, T.D., Hood, S.J., Jensen, J.L., and Poole, B.D. (2019). Combating Vaccine Hesitancy with Vaccine-Preventable Disease Familiarization: An Interview and Curriculum Intervention for College Students. Vaccines, 7.

Gatwood, 2020, Pneumococcal vaccination in older adults: An initial analysis of social determinants of health and vaccine uptake, Vaccine, 38, 5607, 10.1016/j.vaccine.2020.06.077

Kempe, 2020, Parental Hesitancy about Routine Childhood and Influenza Vaccinations: A National Survey, Pediatrics, 146, e20193852, 10.1542/peds.2019-3852

Williams, L., Gallant, A.J., Rasmussen, S., Brown Nicholls, L.A., Cogan, N., Deakin, K., Young, D., and Flowers, P. (2020). Towards intervention development to increase the uptake of COVID-19 vaccination among those at high risk: Outlining evidence-based and theoretically informed future intervention content. Br. J. Health Psychol.

Freeman, 2020, Coronavirus conspiracy beliefs, mistrust, and compliance with government guidelines in England, Psychol. Med., 2020, 1

Bertoncello, C., Ferro, A., Fonzo, M., Zanovello, S., Napoletano, G., Russo, F., Baldo, V., and Cocchio, S. (2020). Socioeconomic Determinants in Vaccine Hesitancy and Vaccine Refusal in Italy. Vaccines, 8.

Lane, 2018, Vaccine hesitancy around the globe: Analysis of three years of WHO/UNICEF Joint Reporting Form data-2015–2017, Vaccine, 36, 3861, 10.1016/j.vaccine.2018.03.063

Zhou, 2019, Trust collapse caused by the Changsheng vaccine crisis in China, Vaccine, 37, 3419, 10.1016/j.vaccine.2019.05.020