Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Cell - Tập 86 Số 1 - Trang 147-157 - 1996
Xuesong Liu1, Caryn Naekyung Kim1, Jie Yang1, Ronald Jemmerson2, Xiaodong Wang1
1Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322 USA
2Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA

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Benveniste, 1995, p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency, Proc. Natl. Acad. Sci. USA, 92, 8373, 10.1073/pnas.92.18.8373

Casciola-Rosen, 1994, Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death, J. Biol. Chem., 269, 30757, 10.1016/S0021-9258(18)47343-7

Cohen, 1978, Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency, Proc. Natl. Acad. Sci. USA, 75, 472, 10.1073/pnas.75.1.472

de Jong, 1994, Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells, Cancer Res., 54, 256

Duan, 1996, ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis, J. Biol. Chem., 271, 1621, 10.1074/jbc.271.3.1621

Eeari, 1995, Apoptosis by a cytosolic extract from Fas-activated cells, EMBO J., 14, 5201, 10.1002/j.1460-2075.1995.tb00204.x

Evans, 1988, The human somatic cytochrome c gene, Proc. Natl. Acad. Sci. USA, 85, 9625, 10.1073/pnas.85.24.9625

Fernandes-Alnemri, 1994, CPP32, a novel human apoptotic protein with homologue to Caenorhabditis elegans cell death protein ced-3 and mammalian interleukin-1β-converting enzyme, J. Biol. Chem., 269, 30761, 10.1016/S0021-9258(18)47344-9

Fernandes-Alnemri, 1995, Mch2, a new member of the apoptotic ced-3/ICE cysteine protease gene family, Cancer Res., 55, 2737

Fernandes-Alnemri, 1995, Mch3, a novel human apoptotic cysteine protease highly related to CPP32, Cancer Res., 55, 6045

Goday, 1985, Human B lymphocytes and thymocytes but not peripheral blood mononuclear cells accumulate high dATP levels in conditions simulating ADA deficiency, Biochem. Pharmacol., 34, 3561, 10.1016/0006-2952(85)90734-8

Gonzales, 1990, Biogenesis of mitochondrial c-type cytochromes, J. Bioenerg. Biomembr., 22, 753, 10.1007/BF00786929

Hayakawa, 1993, Age-assoicated damage in mitochondrial DNA in human hearts, Mol. Cell. Biochem., 119, 95, 10.1007/BF00926859

Hengartner, 1994, C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2, Cell, 76, 665, 10.1016/0092-8674(94)90506-1

Hengartner, 1994, The ins and outs of programmed cell death during C. elegans development, Phil. Trans. Roy. Soc. (Lond). B, 345, 243, 10.1098/rstb.1994.0100

Hengartner, 1992, Caenorhabditis elegans gene ced-9 protects cells from programmed cell death, Nature, 356, 494, 10.1038/356494a0

Hockenbery, 1993, Bcl-2 functions in an antioxidant pathway to prevent apoptosis, Cell, 75, 241, 10.1016/0092-8674(93)80066-N

Jacobson, 1993, Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA, Nature, 361, 365, 10.1038/361365a0

Jemmerson, 1991, Different functional boundaries for the major antigenic region of two cytochromes c, Proc. Natl. Acad. Sci. USA, 88, 4428, 10.1073/pnas.88.10.4428

Jemmerson, 1991, A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells, Eur. J. Immunol., 21, 143, 10.1002/eji.1830210122

Kaufmann, 1993, Specific proteolytic cleavage of poly(ADP-ribose) polymerase, Cancer Res., 53, 3976

Kerr, 1971, Shrinkage necrosis, J. Pathol., 105, 13, 10.1002/path.1711050103

Krajewski, 1993, Investigation of the subcellular distribution of the bcl-2 oncoprotein, Cancer Res., 53, 4701

Lazebnik, 1993, Nuclear events of apoptosis in vitro in cell-free mitotic extracts, J. Cell Biol., 123, 7, 10.1083/jcb.123.1.7

Lazebnik, 1995, Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution, Proc. Natl. Acad. Sci. USA, 92, 9042, 10.1073/pnas.92.20.9042

Liu, 1996, Purification and characterization of an interleukin-1β converting enzyme family of protease that activates cysteine protease p32 (CPP32), J. Biol. Chem., 271, 13371, 10.1074/jbc.271.23.13371

Margoliash, 1967, Cytochrome c from vertebrate and invertebrate sources, Meth. Enzymol., 10, 339, 10.1016/0076-6879(67)10064-5

Martin, 1995, Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis, EMBO J., 14, 5191, 10.1002/j.1460-2075.1995.tb00203.x

Mayer, 1995, Translocation of apocytochrome c across the outer membrane of mitochondria, J. Biol. Chem., 270, 12390, 10.1074/jbc.270.21.12390

Monaghan, 1992, Ultrastructural localization of bcl-2 protein, J. Histochem. Cytochem., 40, 1819, 10.1177/40.12.1453000

Newmeyer, 1994, Cell-free apoptosis in Xenopus egg extracts, Cell, 79, 353, 10.1016/0092-8674(94)90203-8

Nicholson, 1995, Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis, Nature, 376, 37, 10.1038/376037a0

Pai, 1996, Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins (SREBPs), Proc. Natl. Acad. Sci. USA, 93, 5437, 10.1073/pnas.93.11.5437

Reed, 1994, Bcl-2 and the regulation of programmed cell death, J. Cell Biol., 124, 1, 10.1083/jcb.124.1.1

Rueggs, 1989, Staurosporine, K-252 and UCN-01, Trends Pharmacol. Sci., 10, 218, 10.1016/0165-6147(89)90263-0

Schlegel, 1996, CPP32/Apopain is a key interleukin 1β converting enzyme-like protease involved in Fas-mediated apoptosis, J. Biol. Chem., 271, 1841, 10.1074/jbc.271.4.1841

Steller, 1995, Mechanisms and genes of cellular suicide, Science, 267, 1445, 10.1126/science.7878463

Tewari, 1995, Yama/CPP32β, a mammalian homolog of ced-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase, Cell, 81, 801, 10.1016/0092-8674(95)90541-3

Thornberry, 1992, A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes, Nature, 356, 768, 10.1038/356768a0

Wakade, 1995, Deoxynucleoside induces neuronal apoptosis independent of neurotrophic factors, J. Biol. Chem., 270, 17986, 10.1074/jbc.270.30.17986

Wang, 1993, Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter, J. Biol. Chem., 268, 14497, 10.1016/S0021-9258(19)85266-3

Wang, 1995, Purification of an interleukin-1β converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains, J. Biol. Chem., 270, 18044, 10.1074/jbc.270.30.18044

Wang, 1996, Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis, EMBO J., 15, 1012, 10.1002/j.1460-2075.1996.tb00438.x

White, 1996, Life, death, and the pursuit of apoptosis, Genes Dev., 10, 1, 10.1101/gad.10.1.1

Wyllie, 1980, Glucocorticiod-induced thymocyte apoptosis is associated with endogenous endonuclease activation, Nature, 284, 555, 10.1038/284555a0

Wyllie, 1980, Cell death, Int. Rev. Cytol., 68, 251, 10.1016/S0074-7696(08)62312-8

Xue, 1995, Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein, Nature, 377, 248, 10.1038/377248a0

Yuan, 1990, Genetics mosaic analysis of ced-3 and ced-4, two genes that control programmed cell death in the nematode C. elegans, Dev. Biol., 138, 33, 10.1016/0012-1606(90)90174-H

Yuan, 1993, The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β converting enzyme, Cell, 75, 641, 10.1016/0092-8674(93)90485-9