Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease

International Journal of Neuropsychopharmacology - Tập 15 Số 01 - Trang 77-90 - 2012
Chia-Hsiung Chen1, Weihui Zhou2,1, Shengchun Liu3,1, Yu Deng1, Fang Cai1, Masahide Tone4, Yukiko Tone4, Yigang Tong1, Weihong Song2,1
1Townsend Family Laboratories, Department of Psychiatry, Brain Research Center, Graduate Program in Neuroscience, The University of British Columbia, Vancouver, Canada
2Ministry of Education Key Laboratory of Child Development and Disorders, The Pediatrics Institute, Children's Hospital, Chongqing Medical University, Chongqing, China
3Department of surgery, the first affiliated hospital, Chongqing Medical University, Chongqing, China
4Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA USA

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Schreck, 1991, EMBO Journal, 10, 2247, 10.1002/j.1460-2075.1991.tb07761.x

10.1042/BST0350574

10.1093/nar/gkh348

10.1016/S0306-4522(99)00089-5

10.1073/pnas.0308576101

Qing, 2004, FASEB Journal, 18, 1571, 10.1096/fj.04-1994fje

10.1016/S0065-230X(08)60257-2

10.1096/fj.05-4986com

10.1038/sj.embor.7400166

10.1016/S0304-3940(97)00797-0

10.1073/pnas.94.6.2642

10.1146/annurev.cb.10.110194.002201

10.1074/jbc.273.20.12341

10.1146/annurev.immunol.16.1.225

Gapuzan, 2005, Oncogene, 24, 6574, 10.1038/sj.onc.1208809

10.1073/pnas.0503839103

10.1128/MCB.26.9.3353-3364.2006

10.1523/JNEUROSCI.4396-06.2007

10.1128/MCB.24.2.865-874.2004

10.1111/j.1471-4159.2007.05167.x

10.1126/science.2218531

10.1074/jbc.M706579200

10.1016/j.neuron.2008.02.024

10.1002/jnr.21252

10.1038/35102591

10.1006/nbdi.2001.0451

10.1523/JNEUROSCI.5065-07.2008

10.1016/0092-8674(94)90131-7

10.1073/pnas.92.20.9328

10.1016/S0168-0102(02)00004-4

10.1146/annurev.immunol.14.1.649

10.1007/s00702-004-0255-3

10.1146/annurev.iy.12.040194.001041

10.1074/jbc.M109889200

10.1016/j.neuron.2007.05.012

10.1016/0006-8993(96)00310-1

10.1096/fj.04-3426com

10.1096/fj.05-5628com

10.1096/fj.05-5632com

10.1073/pnas.0606298103

10.3109/10715769209079515