In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients

Immunopharmacology - Tập 35 Số 3 - Trang 229-235 - 1997
Darryl M. See1, Nikki Broumand2, Lisa Sahl2, Jeremiah G. Tilles2
1Department of Medicine, U.C. Irvine Medical Center, Orange 92668, USA.
2Department of Medicine, Division of Infectious Diseases, U.C. Irvine Medical Center, 101 The City Dr., Orange, CA 92668, USA

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Ablashi, 1988, Utilization of human hemapoietic cell lines for the propogation and characterization of HBLV (human herpesvirus 6), Int. J. Cancer, 42, 787, 10.1002/ijc.2910420526

Brook, 1993, Interferon alpha therapy for patients with chronic fatigue syndrome, J. Infect. Dis., 168, 791, 10.1093/infdis/168.3.791

Cai, 1990, Natural killer cell responses in homosexual men with early HIV infection, J. Acquired Immune Defic. Syndr., 3, 669

Emmanuel et al., 1994.

Forthal, 1995, Functional activities of 20 Human Immunodeficiency Virus Type 1 (HIV-1)-specific human monoclonal antibodies, AIDS Res. Hum. Retroviruses, 11, 1095, 10.1089/aid.1995.11.1095

Gupta, 1991, A comprehensive immunologic analysis in chronic fatigue syndrome, Scand. J. Immunol., 33, 319, 10.1111/j.1365-3083.1991.tb01777.x

Hobbs, 1989

Holmes, 1988, Chronic Fatigue Syndrome: a working case definition, Ann. Intern. Med., 108, 387, 10.7326/0003-4819-108-3-387

Jenkins, 1993, Natural killer cytotoxicity and antibody-dependent cellular cytotoxicity of human immunodeficiency virus-infected cells by leukocytes from human neonates and adults, Pediatric Res., 33, 469, 10.1203/00006450-199305000-00010

Kibler, 1985, Immune function in chronic active Epstein-Barr virus infection, J. Clin. Immunol., 5, 46, 10.1007/BF00915168

Kikuta, 1990, Interferon induction by human herpesvirus 6 in human mononuclear cells, J. Infect. Dis., 162, 35, 10.1093/infdis/162.1.35

Kim, 1990, Panax ginseng as a potential immunomodulator: studies in mice, Immunopharmacol. Immunotoxicol., 12, 257, 10.3109/08923979009019672

Kovacs, 1995, Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodifciency virus infection, 332, 567

Lersch, 1992, Nonspecific immunostimulation with low doses of cyclophosphamide (LDCY), thymostimulin, and Echinacea purpurea extracts (echinacin) in patients with far advanced colorectal cancers: preliminary results, Cancer Invest., 10, 343, 10.3109/07357909209024793

Liu, 1992, Recent advances on ginseng research in China, J. Ethnopharmacol., 36, 27, 10.1016/0378-8741(92)90057-X

Lloyd, 1990, A double-blind, placebo-controlled trial of intravenous immunoglobulin therapy in patients with the chronic fatigue syndrome, Am. J. Med., 89, 561, 10.1016/0002-9343(90)90173-B

Luettig, 1989, Macrophage activation by the polysaccharide arabinogalactan from the plant cell cultures of Echinacea purpurea, J. Natl. Cancer Inst., 81, 669, 10.1093/jnci/81.9.669

Lusso, 1993, Infection of natural killer cells by human herpesvirus 6, Nature, 363, 458, 10.1038/362458a0

Mengs, 1991, Toxicity of Echinacea purpurea, 41, 1076

Mizuno, 1994, Differences in immunomodulating effects between wild and cultured Panax ginseng, Biochem. Biophys. Res. Commun., 200, 1672, 10.1006/bbrc.1994.1644

Phillips, 1995, Herbs and HIV: the health food industy's answer, South. Med. J., 88, 911, 10.1097/00007611-199509000-00004

Pross, H., Baines, M., Rubin, P., Shragge, P. and Patterson, M., Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity. J. Clin. Immunol. 1: 51–63.

Roesler, J., Emmendorfer, A., Steinmuller, C., Luettig, B., Wagner, H. and Lohmann-Matthes, M., Application of purified polysaccarides from cell cultures of the plant Echinacea purpurea to test subjects mediates activation of the phagocytic system. Int. J. Immunopharmacol. 13: 931–941.

Scaglione, 1990, Immunomodulatory effects of two extracts of Panax ginseng C.A. Meyer, Drugs Exp. Clin. Res., 16, 537

Scott-Algara, 1992, Natural killer (NK) cell activity during HIV infection: a decrease in NK activity is observed at the clonal level and is not restored after in vitro long-term culture of NK cells, Clin. Exp. Immunol., 90, 181, 10.1111/j.1365-2249.1992.tb07925.x

Singh, 1984, Immunomodulatory effects of Panax ginseng extract, Planta Med., 6, 459

Steeper, 1990, The spectrum of clinical and laboratory findings resulting from human herpesvirus-6 (HHV-6) in patients with mononucleosis-like illnesses not resulting from Epstein-Barr virus or cy-tomegalovirus, Am. J. Clin. Pathol., 93, 776, 10.1093/ajcp/93.6.776

Steinmuller, 1993, Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes, Int. J. Immunopharmacol., 15, 605, 10.1016/0192-0561(93)90078-D

Strayer, 1994, A controlled clinical trial with a specifically configured RNA drug, poly(I)-poly(C12U), in chronic fatigue syndrome, Clin. Infec. Dis., 18, S88, 10.1093/clinids/18.Supplement_1.S88

Zhou, 1985, Bio-modulation: A modern interpretation of traditional Chinese medicine, 3