Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors
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Dai, 2015, Cardiovascular physiology in the older adults, J Geriatr Cardiol, 12, 196
Vanoverschelde, 1993, Contribution of left ventricular diastolic function to exercise capacity in normal subjects, J Appl Physiol (1985), 74, 2225, 10.1152/jappl.1993.74.5.2225
Upadhya, 2015, Heart failure with preserved ejection fraction in the elderly: scope of the problem, J Mol Cell Cardiol, 83, 73, 10.1016/j.yjmcc.2015.02.025
Douglas, 2003, The left atrium: a biomarker of chronic diastolic dysfunction and cardiovascular disease risk, J Am Coll Cardiol, 42, 1206, 10.1016/S0735-1097(03)00956-2
Medrano, 2016, Left atrial volume and pulmonary artery diameter are noninvasive measures of age-related diastolic dysfunction in mice, J Gerontol A Biol Sci Med Sci, 71, 1141, 10.1093/gerona/glv143
Tsang, 2001, Left atrial volume: important risk marker of incident atrial fibrillation in 1655 older men and women, Mayo Clin Proc, 76, 467, 10.4065/76.5.467
Shaikh, 2013, Left atrial volumes and associated stroke subtypes, BMC Neurol, 13, 149, 10.1186/1471-2377-13-149
Zieman, 2005, Mechanisms, pathophysiology, and therapy of arterial stiffness, Arterioscler Thromb Vasc Biol, 25, 932, 10.1161/01.ATV.0000160548.78317.29
Lesnefsky, 2016, Mitochondrial metabolism in aging heart, Circ Res, 118, 1593, 10.1161/CIRCRESAHA.116.307505
Hyyti, 2010, Aging impairs myocardial fatty acid and ketone oxidation and modifies cardiac functional and metabolic responses to insulin in mice, Am J Physiol Heart Circ Physiol, 299, H868, 10.1152/ajpheart.00931.2009
Hansford, 1978, Lipid oxidation by heart mitochondria from young adult and senescent rats, Biochem J, 170, 285, 10.1042/bj1700285
McMillin, 1993, Mitochondrial metabolism and substrate competition in the aging Fischer rat heart, Cardiovasc Res, 27, 2222, 10.1093/cvr/27.12.2222
Cieslik, 2011, Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart, J Mol Cell Cardiol, 50, 248, 10.1016/j.yjmcc.2010.10.019
Wang, 2015, Age-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteries, J Mol Cell Cardiol, 83, 101, 10.1016/j.yjmcc.2015.02.004
Aquilano, 2014, Glutathione: new roles in redox signaling for an old antioxidant, Front Pharmacol, 5, 196, 10.3389/fphar.2014.00196
Michael, 2011, The ageing lens and cataract: a model of normal and pathological ageing, Philos Trans R Soc Lond B Biol Sci, 366, 1278, 10.1098/rstb.2010.0300
Xiong, 2011, S-glutathionylation: from molecular mechanisms to health outcomes, Antioxid Redox Signal, 15, 233, 10.1089/ars.2010.3540
Aruoma, 1989, The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid, Free Radic Biol Med, 6, 593, 10.1016/0891-5849(89)90066-X
Nguyen, 2013, Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione, Aging Cell, 12, 415, 10.1111/acel.12073
Moreno-Ulloa, 2015, Recovery of indicators of mitochondrial biogenesis, oxidative stress, and aging with (-)-epicatechin in senile mice, J Gerontol A Biol Sci Med Sci, 70, 1370, 10.1093/gerona/glu131
Taffet, 1996, Noninvasive indexes of cardiac systolic and diastolic function in hyperthyroid and senescent mouse, Am J Physiol, 270, H2204
Hartley, 1997, Noninvasive determination of pulse-wave velocity in mice, Am J Physiol, 273, H494
Zuker, 2003, Mfold web server for nucleic acid folding and hybridization prediction, Nucleic Acids Res, 31, 3406, 10.1093/nar/gkg595
SantaLucia, 1998, A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics, Proc Natl Acad Sci USA, 95, 1460, 10.1073/pnas.95.4.1460
Peyret, 2000, Melt Curve Analysis for Each Primer Pair Resulted in a Single Peak Indicating a Single PCR Product
Bustin, 2009, The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments, Clin Chem, 55, 611, 10.1373/clinchem.2008.112797
Cordero-Reyes, 2014, Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function, J Mol Cell Cardiol, 68, 98, 10.1016/j.yjmcc.2013.12.029
Hamilton, 2016, Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure, Am J Physiol Heart Circ Physiol, 310, H667, 10.1152/ajpheart.00746.2015
Sano, 2001, ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts, Circ Res, 89, 661, 10.1161/hh2001.098873
Lakshminarayanan, 2001, Reactive oxygen intermediates induce monocyte chemotactic protein-1 in vascular endothelium after brief ischemia, Am J Pathol, 159, 1301, 10.1016/S0002-9440(10)62517-5
Trial, 2017, Dissecting the role of myeloid and mesenchymal fibroblasts in age-dependent cardiac fibrosis, Basic Res Cardiol, 112, 34, 10.1007/s00395-017-0623-4
Zhang, 2016, NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice, Science, 352, 1436, 10.1126/science.aaf2693
Cieslik, 2015, Mesenchymal stem cell-derived inflammatory fibroblasts promote monocyte transition into myeloid fibroblasts via an IL-6-dependent mechanism in the aging mouse heart, FASEB J, 29, 3160, 10.1096/fj.14-268136
Dai, 2012, Cardiac aging: from molecular mechanisms to significance in human health and disease, Antioxid Redox Signal, 16, 1492, 10.1089/ars.2011.4179
Cieslik, 2014, Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts, J Mol Cell Cardiol, 70, 56, 10.1016/j.yjmcc.2013.10.017
Tsai, 2015, TNF-α down-regulates sarcoplasmic reticulum Ca²⁺ ATPase expression and leads to left ventricular diastolic dysfunction through binding of NF-κB to promoter response element, Cardiovasc Res, 105, 318, 10.1093/cvr/cvv008
Balderas-Villalobos, 2013, Oxidative stress in cardiomyocytes contributes to decreased SERCA2a activity in rats with metabolic syndrome, Am J Physiol Heart Circ Physiol, 305, H1344, 10.1152/ajpheart.00211.2013
Deckert-Schlüter, 1997, Interleukin-10 downregulates the intracerebral immune response in chronic Toxoplasma encephalitis, J Neuroimmunol, 76, 167, 10.1016/S0165-5728(97)00047-7
Suzuki, 2000, IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii, J Immunol, 164, 5375, 10.4049/jimmunol.164.10.5375
Gazzinelli, 1996, In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha, J Immunol, 157, 798, 10.4049/jimmunol.157.2.798
Sikka, 2013, Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age, Exp Gerontol, 48, 128, 10.1016/j.exger.2012.11.001
Lenaz, 1997, Mitochondrial complex I defects in aging, Mol Cell Biochem, 174, 329, 10.1023/A:1006854619336
Brown, 2017, Expert consensus document: Mitochondrial function as a therapeutic target in heart failure, Nat Rev Cardiol, 14, 238, 10.1038/nrcardio.2016.203
Sekhar, 2011, Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation, Am J Clin Nutr, 94, 847, 10.3945/ajcn.110.003483
Pérez, 2009, Is the oxidative stress theory of aging dead, Biochim Biophys Acta, 1790, 1005, 10.1016/j.bbagen.2009.06.003
Ristow, 2009, Antioxidants prevent health-promoting effects of physical exercise in humans, Proc Natl Acad Sci USA, 106, 8665, 10.1073/pnas.0903485106
Dey, 2016, Compartment-specific control of reactive oxygen species scavenging by antioxidant pathway enzymes, J Biol Chem, 291, 11185, 10.1074/jbc.M116.726968
Owada, 2017, Resolution of mitochondrial oxidant stress improves aged-cardiovascular performance, Coron Artery Dis, 28, 33, 10.1097/MCA.0000000000000434
Dai, 2009, Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging, Circulation, 119, 2789, 10.1161/CIRCULATIONAHA.108.822403
Qin, 2013, Hydrogen peroxide-mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart, J Am Heart Assoc, 2, e000184, 10.1161/JAHA.113.000184
Grek, 2013, Causes and consequences of cysteine S-glutathionylation, J Biol Chem, 288, 26497, 10.1074/jbc.R113.461368
Pan, 2005, Cytoprotection by glycine against ATP-depletion-induced injury is mediated by glycine receptor in renal cells, Biochem J, 390, 447, 10.1042/BJ20050141