Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

Drug Metabolism and Disposition - Tập 38 Số 1 - Trang 92-99 - 2010
Miho Kazui1, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda, Atsushi Kurihara
1Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-Ku, Tokyo, 140-8710, Japan. [email protected]

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