ITMIG Consensus Statement on the Use of the WHO Histological Classification of Thymoma and Thymic Carcinoma: Refined Definitions, Histological Criteria, and Reporting

Journal of Thoracic Oncology - Tập 9 Số 5 - Trang 596-611 - 2014
Alexander Marx1, Philipp Ströbel1,2, Sunil Badve3, Lara Chalabreysse4, John Chan5, Gang Chen6, Laurence de Leval7, Frank Detterbeck8, Nicolas Girard9, James Huang10, Michael Kurrer11, Libero Lauriola12, Mirella Marino13, Yoshihiro Matsuno14, Thierry Jo Molina15, Kiyoshi Mukai16, Andrew G. Nicholson17, Daisuke Nonaka18, Ralf J. Rieker19, Juan Rosaí20, Enrico Ruffini21, William D. Travis22
1Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany
2Institute of Pathology, University of Göttingen, Göttingen, Germany
3 ‡Department of Pathology, Indiana University Health Pathology Laboratory, Indianapolis, Indiana
4Department of Pathology, Louis Pradel Hospital, Hospices Civils de Lyon, Lyon, France
5Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China
6Department of Pathology, Shanghai Pulmonary Hospital and Tongji University School of Medicine, Shanghai, China
7University Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
8Department of Thoracic Surgery, Yale University School of Medicine, New Haven, Connecticut
9Department of Respiratory Medicine, Louis Pradel Hospital, Hospices Civils de Lyon, Lyon, France
10Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
11Division of Pathology, Zurich, Switzerland
12Department of Pathology, Catholic University, Rome, Italy
13Department of Pathology, Regina Elena National Cancer Institute, Rome, Italy
14Department of Diagnostic Pathology, Hokkaido University Hospital, Sapporo, Japan
15Department of Pathology, AP-HP, Necker, University Paris Descartes, Paris, France
16Department of Diagnostic Pathology, Saiseikai Central Hospital, Tokyo, Japan
17Diagnostic Thoracic Pathology, Royal Brompton Hospital, and Imperial College London, London, United Kingdom
18 §§§Department of Histopathology, The Cristie Hospital, and Institute of Cancer Sciences, The University of Manchester, Manchester, United Kingdom
19Institute of Pathology, University of Erlangen, Erlangen, Germany
20Centro Diagnostico Italiano, Milano, Italy
21Department of Thoracic Surgery, University of Torino, Torino, Italy
22Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York

Tóm tắt

Từ khóa


Tài liệu tham khảo

Rosai, 1999

Müller-Hermelink, 2004, 148

Levine, 1978, Thymic hyperplasia and neoplasia: a review of current concepts, Hum Pathol, 9, 495, 10.1016/S0046-8177(78)80131-2

Suster, 1999, Thymoma, atypical thymoma, and thymic carcinoma. A novel conceptual approach to the classification of thymic epithelial neoplasms, Am J Clin Pathol, 111, 826, 10.1093/ajcp/111.6.826

Okumura, 2002, Oncological significance of WHO histological thymoma classification. A clinical study based on 286 patients, Jpn J Thorac Cardiovasc Surg, 50, 189, 10.1007/BF03032284

Ströbel, 2004, Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: a retrospective analysis, J Clin Oncol, 22, 1501, 10.1200/JCO.2004.10.113

Vandiedonck, 2009, Association of HLA-A in autoimmune myasthenia gravis with thymoma, J Neuroimmunol, 210, 120, 10.1016/j.jneuroim.2009.02.004

Ströbel, 2007, Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1), J Pathol, 211, 563, 10.1002/path.2141

Suster, 2005, Problem areas and inconsistencies in the WHO classification of thymoma, Semin Diagn Pathol, 22, 188, 10.1053/j.semdp.2006.02.004

Rieker, 2002, Histologic classification of thymic epithelial tumors: comparison of established classification schemes, Int J Cancer, 98, 900, 10.1002/ijc.10255

Verghese, 2008, Interobserver variation in the classification of thymic tumours—A multicentre study using the WHO classification system, Histopathology, 53, 218, 10.1111/j.1365-2559.2008.03088.x

Jain, 2010, WHO types A and AB thymomas: not always benign, Mod Pathol, 23, 1641, 10.1038/modpathol.2010.172

Moran, 2010, Invasive spindle cell thymomas (WHO Type A): a clinicopathologic correlation of 41 cases, Am J Clin Pathol, 134, 793, 10.1309/AJCP7KBP4QQLRLXW

Nonaka, 2012, Is there a spectrum of cytologic atypia in type a thymomas analogous to that seen in type B thymomas? A pilot study of 13 cases, Am J Surg Pathol, 36, 889, 10.1097/PAS.0b013e31824fff50

Vladislav, 2013, The role of histology in predicting recurrence of type A thymomas: a clinicopathologic correlation of 23 cases, Mod Pathol, 26, 1059, 10.1038/modpathol.2013.49

Detterbeck, 2006, Clinical value of the WHO classification system of thymoma, Ann Thorac Surg, 81, 2328, 10.1016/j.athoracsur.2005.11.067

Ströbel, 2014, Corticomedullary differentiation and maturational arrest in thymomas, Histopathology, 64, 557, 10.1111/his.12279

Suster, 1999, Micronodular thymoma with lymphoid B-cell hyperplasia: clinicopathologic and immunohistochemical study of eighteen cases of a distinctive morphologic variant of thymic epithelial neoplasm, Am J Surg Pathol, 23, 955, 10.1097/00000478-199908000-00014

Tateyama, 2001, The spectrum of micronodular thymic epithelial tumours with lymphoid B-cell hyperplasia, Histopathology, 38, 519, 10.1046/j.1365-2559.2001.01133.x

Ströbel, 2005, Micronodular thymoma: an epithelial tumour with abnormal chemokine expression setting the stage for lymphoma development, J Pathol, 207, 72, 10.1002/path.1808

Marchevsky, 2008, Thymic epithelial neoplasms: a review of current concepts using an evidence-based pathology approach, Hematol Oncol Clin North Am, 22, 543, 10.1016/j.hoc.2008.03.006

Cardillo, 2010, Predictors of survival in patients with locally advanced thymoma and thymic carcinoma (Masaoka stages III and IVa), Eur J Cardiothorac Surg, 37, 819, 10.1016/j.ejcts.2009.11.001

Marchevsky, 2008, Evidence-based pathology and the pathologic evaluation of thymomas: the World Health Organization classification can be simplified into only 3 categories other than thymic carcinoma, Cancer, 112, 2780, 10.1002/cncr.23492

Ströbel, 2010, Thymoma and thymic carcinoma: molecular pathology and targeted therapy, J Thorac Oncol, 5, S286, 10.1097/JTO.0b013e3181f209a8

Marx, 2011, Thymic carcinoma: is it a separate entity? From molecular to clinical evidence, Thorac Surg Clin, 21, 25, 10.1016/j.thorsurg.2010.08.010

Weissferdt, 2012, Thymic carcinoma, part 1: a clinicopathologic and immunohistochemical study of 65 cases, Am J Clin Pathol, 138, 103, 10.1309/AJCP88FZTWANLRCB

Moran, 2008, Thymic carcinoma: current concepts and histologic features, Hematol Oncol Clin North Am, 22, 393, 10.1016/j.hoc.2008.03.002

Kojika, 2009, Immunohistochemical differential diagnosis between thymic carcinoma and type B3 thymoma: diagnostic utility of hypoxic marker, GLUT-1, in thymic epithelial neoplasms, Mod Pathol, 22, 1341, 10.1038/modpathol.2009.105

Kaira, 2010, Biologic correlation of 2-[18F]-fluoro-2-deoxy-D-glucose uptake on positron emission tomography in thymic epithelial tumors, J Clin Oncol, 28, 3746, 10.1200/JCO.2009.27.4662

Hishima, 1994, CD5 expression in thymic carcinoma, Am J Pathol, 145, 268

Henley, 2004, Tyrosine kinase receptor expression in thymomas, J Cancer Res Clin Oncol, 130, 222, 10.1007/s00432-004-0545-z

Moran, 2000, On the histologic heterogeneity of thymic epithelial neoplasms. Impact of sampling in subtyping and classification of thymomas, Am J Clin Pathol, 114, 760, 10.1309/CYJH-9RXM-P2PK-120J

Wick, 2010, Histopathologic prognosis of thymomas: another example of medical surrogacy, Am J Clin Pathol, 134, 703, 10.1309/AJCPF4KT2PEXZUSD

Engel, 1999, Thymic tumours in Denmark. A retrospective study of 213 cases from 1970-1993, Pathol Res Pract, 195, 565, 10.1016/S0344-0338(99)80006-5

Chen, 2002, New WHO histologic classification predicts prognosis of thymic epithelial tumors: a clinicopathologic study of 200 thymoma cases from China, Cancer, 95, 420, 10.1002/cncr.10665

Okumura, 2007, Outcome of surgical treatment for recurrent thymic epithelial tumors with reference to World Health Organization histologic classification system, J Surg Oncol, 95, 40, 10.1002/jso.20671

Chalabreysse, 2002, Correlation of the WHO schema for the classification of thymic epithelial neoplasms with prognosis: a retrospective study of 90 tumors, Am J Surg Pathol, 26, 1605, 10.1097/00000478-200212000-00008

Suster, 2006, Thymoma classification: current status and future trends, Am J Clin Pathol, 125, 542, 10.1309/CAV8RNU5TKNACKNC

Nakagawa, 2005, Immunohistochemical KIT (CD117) expression in thymic epithelial tumors, Chest, 128, 140, 10.1378/chest.128.1.140

Jaffe, 2008, 267

Buckley, 2001, Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis, Ann Neurol, 50, 64, 10.1002/ana.1017

Ströbel, 2002, Paraneoplastic myasthenia gravis correlates with generation of mature naive CD4(+) T cells in thymomas, Blood, 100, 159, 10.1182/blood.V100.1.159

Hartert, 2010, A follicular dendritic cell sarcoma of the mediastinum with immature T cells and association with myasthenia gravis, Am J Surg Pathol, 34, 742, 10.1097/PAS.0b013e3181d7a2ee

Kim, 2010, Follicular dendritic cell sarcoma with immature T-cell proliferation, Hum Pathol, 41, 129, 10.1016/j.humpath.2009.05.014

Moran, 2012, Thymomas II: a clinicopathologic correlation of 250 cases with a proposed staging system with emphasis on pathologic assessment, Am J Clin Pathol, 137, 451, 10.1309/AJCP36ALGUZWOSEA

Travis, 2011, International association for the study of lung cancer/American thoracic society/European respiratory society international multidisciplinary classification of lung adenocarcinoma, J Thorac Oncol, 6, 244, 10.1097/JTO.0b013e318206a221