Homocystéine, vitamine B12 et acide folique dans le déclin cognitif chez les personnes âgées
Tài liệu tham khảo
Malouf, 2008, Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people, Cochrane Database Syst Rev, 4, 1
Sjögren, 2006, Cholesterol and Alzheimer's disease-is there a relation?, Mech Ageing Dev, 127, 138, 10.1016/j.mad.2005.09.020
Solfrizzy, 2006, Dietary intake of unsaturated fatty acids ans age-related cognitive decline: a 8.5-years follow-up of the Italian longitudinal study on aging, Neurobiol Aging, 27, 1694, 10.1016/j.neurobiolaging.2005.09.026
Blennow, 2006, Alzheimer's disease, Lancet, 368, 387, 10.1016/S0140-6736(06)69113-7
Moller, 1998, The case described by Alois Alzheimer in 1911. Historical and conceptual perspectives based on the clinical record and neurohistological sections, Eur Arch Psychiatry Clin Neurosci, 248, 111, 10.1007/s004060050027
De la Torre, 2004, Alzheimer's disease is a vasocognopathy: a new term to describe its nature, Neurol Res, 26, 517, 10.1179/016164104225016254
De la Torre, 2004, Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma and dialectics, Lancet Neurol, 3, 184, 10.1016/S1474-4422(04)00683-0
Gorelick, 2004, Risk factors for vascular dementia and Alzheimer disease, Stroke, 35, 2620, 10.1161/01.STR.0000143318.70292.47
Blaise, 2007, Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats, Am J Pathol, 170, 667, 10.2353/ajpath.2007.060339
Mattson, 2003, Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders, Trends Neurosci, 26, 137, 10.1016/S0166-2236(03)00032-8
Mudd, 1985, The natural history of homocystinuria due to cystathionine beta-Synthase deficiency, Am J Hum Genet, 37, 1
Grieco, 1977, Homocystinuria: pathogenetic mechanisms, Am J Med Sci, 273, 120, 10.1097/00000441-197703000-00001
Seshadri, 2002, Plasma Homocysteine as a risk factor for dementia and Alzheimer's disease, N Engl J Med, 346, 476, 10.1056/NEJMoa011613
Isobe, 2005, Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease, Life Sciences, 77, 1836, 10.1016/j.lfs.2005.02.014
Lehmann, 1999, Identification of cognitive impairment in the elderly: homocysteine is an early marker, Dement Geriatr Cogn Disord, 10, 12, 10.1159/000017092
Obeid, 2007, Folate and Methylation Status in Relation to Phosphorylated Tau Protein (181P) and β-Amyloid (1-42) in Cerebrospinal Fluid, Clin Chem, 53, 1129, 10.1373/clinchem.2006.085241
Serot, 2005, Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease, J Neurol Neurosurg Psychiatr, 76, 1585, 10.1136/jnnp.2004.056119
Blom, 2000, Consequences of homocysteine export and oxidation in the vascular system, Semin Thromb Hemost, 26, 187, 10.1055/s-2000-8467
Mudd, 2000, Homocysteine and its disulfide derivatives: a suggested consensus terminology, Arterioscler Thromb Vasc Biol, 20, 1704, 10.1161/01.ATV.20.7.1704
Ichinohe, 2005, Cystathionine beta-Synthase is enriched in the brains of down's patients, Biochem Biophys Res Commun, 338, 1547, 10.1016/j.bbrc.2005.10.118
Oltean, 2003, Nutritional modulation of gene expression and homocysteine utilization by vitamin B12, J Biol Chem, 278, 20778, 10.1074/jbc.M300845200
Guilland, 2003, Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?, Pathol Biol, 51, 101, 10.1016/S0369-8114(03)00104-4
Chdwick, 2000, Betaine homocysteine methytransferase 2: cDNA cloning, gene sequence, physical mapping, and expression of the humain and mouse genes, Genomics, 70, 66, 10.1006/geno.2000.6319
Grieve, 1992, Synaptosomal plasma membrane transport of excitatory sulfur amino acid transmitter candidates: kinetic characterization and analysis of carrier specificity, J Neurosci Res, 32, 60, 10.1002/jnr.490320108
Griffiths, 1992, Neuronal and glial plasma membrane carrier mediated uptake of L-homocysteate is not selectively blocked by beta p chlorophenylglutamate, Neurosci Lett, 147, 175, 10.1016/0304-3940(92)90588-X
Ho, 2003, Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine, Neurobiol Dis, 14, 32, 10.1016/S0969-9961(03)00070-6
Obeid, 2006, Mechanisms of homocystéine neurotoxicity in neurodegenerative diseases with special reference to dementia, FEBS letters, 580, 2994, 10.1016/j.febslet.2006.04.088
Bailey, 1999, Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement, J Nutr, 129, 919, 10.1093/jn/129.5.919
Namour, 2001, Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood, Blood, 97, 1092, 10.1182/blood.V97.4.1092
Hustad, 2000, Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism, Clin Chem, 46, 1065, 10.1093/clinchem/46.8.1065
De Bree, 2001, Association between B vitamin intake and plasma homocysteine concentration in the general Dutch population aged 20–65 y, Am J Clin Nutr, 731, 1027, 10.1093/ajcn/73.6.1027
Jacques, 2001, Determinants of plasma total homocysteine concentration in the Framingham offspring cohort, Am J Clin Nutr, 73, 613, 10.1093/ajcn/73.3.613
De Bree, 2002, Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease, Pharmacol Rev, 54, 599, 10.1124/pr.54.4.599
Ueland, 1992, Plasma homocysteine and cardiovascular disease
Hultberg, 1993, Elevated plasma homocysteine in alcoholics, Alcohol Clin Exp Res, 17, 687, 10.1111/j.1530-0277.1993.tb00820.x
O.M.S, 1992
Fryer, 1993, Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells, Arterioscler Thromb, 13, 1327, 10.1161/01.ATV.13.9.1327
Rodgers, 1986, Activation of endogenous factor V by a homocysteine induced vascular endothelial cell activator, J Clin Invest, 77, 1909, 10.1172/JCI112519
Wolters, 2004, Age-associated changes in the metabolism of vitamin B(12) and folic acid: prevalence, aetiopathogenesis and pathophysiological consequences, Z Gerontol Geriatr, 37, 109, 10.1007/s00391-004-0169-6
Wald, 2002, Homocysteine and cardiovascular disease: evidence on causality from a metaanalysis, BMJ, 325, 1202, 10.1136/bmj.325.7374.1202
Bots, 1999, Homocysteine and short-term risk of myocardial infarction and stroke in the elderly: the Rotterdam Study, Arch Intern Med, 159, 38, 10.1001/archinte.159.1.38
Kittner, 1999, Homocystéine and risk of cerebral infarction in a biracial population: the stroke prevention in young women study, Stroke, 30, 1554, 10.1161/01.STR.30.8.1554
Drunat, 2001, Homocysteine-induced decrease in endothelin-1 production is initiated at the extracellular level and involves oxidative products, Eur J Biochem, 268, 5287, 10.1046/j.0014-2956.2001.02460.x
Lentz, 2001, Homocysteine cardiovascular physiology
Smach, 2001, Folate and Homocysteine in the cerebral fluid of patients with Alzheimer's disease or dementia: a case contol study, Euro Neurol, 65, 270, 10.1159/000326301
Alexopoulos, 2009, Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia, J Am Geriatr Soc, 57, 737, 10.1111/j.1532-5415.2009.02212.x
Zhuo, 2010, Acceleration of brain amyloidosis in an Alzheimer's disease mouse model by a folate, vitamin B6 and B12-deficient diet, Exp Gerontol, 45, 195, 10.1016/j.exger.2009.12.005
Hasegawa, 2005, Homocysteic acid induces intraneuronal accumulation of neurotoxic Abeta42: implications for the pathogenesis of Alzheimer's disease, J Neurosci Res, 80, 869, 10.1002/jnr.20514
Anello, 2004, Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease, Neuroreport, 15, 859, 10.1097/00001756-200404090-00025
Fernandez, 2005, Is MTHFR polymorphism a risk factor for Alzheimer's disease like APOE?, Arq Neuropsiquiatr, 63, 1, 10.1590/S0004-282X2005000100001
Olsewski, 1993, Homocysteine metabolism and the oxidative modification of proteins and lipids, Free Radic Biol Med, 14, 683, 10.1016/0891-5849(93)90151-J
Zappacosta, 2001, Is homocysteine a pro-oxidant?, Free Radic Res, 35, 499, 10.1080/10715760100301511
Vitvitsky, 2003, Redox regulation of homocysteine-dependent glutathione synthesis, Redox Rep, 8, 57, 10.1179/135100003125001260
Volicer, 1990, Involvement of free radicals in dementia of the Alzheimer type: a hypothesis, Neurobiol Aging, 11, 567, 10.1016/0197-4580(90)90119-K
Outinen, 1999, Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells, Blood, 94, 959, 10.1182/blood.V94.3.959.415k20_959_967
Zou, 2005, Homocysteine and redox signaling, Antioxid Redox Signal, 7, 547, 10.1089/ars.2005.7.547
Maclearn, 2002, Cystathionine beat synthase is coordinately regulated with proliferation through a redox sensitive mechanism in cultured humain cells and saccharomyces cerevisiae, J Cell Physiol, 192, 81, 10.1002/jcp.10118
Vitvitsky, 2004, Perturbations in homlocysteine linked redox homoestasis in a murine model for hyperhomocysteinemia, Am J Physiol Regul Integr Comp Physiol, 287, R39, 10.1152/ajpregu.00036.2004
Ho, 2001, Homocysteine potentiates betaamyloid neurotoxicity: role of oxidative stress, J Neurochem, 78, 249, 10.1046/j.1471-4159.2001.00384.x
Parsons, 1998, In vitro effect of the cysteine metabolites homocysteine and cysteic acid upon human neuronal cell lines, Neurotoxicology, 19, 599
Kruman, 2000, Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity, J Neurosci, 20, 6920, 10.1523/JNEUROSCI.20-18-06920.2000
Shea, 2002, Folate quenches oxidative damage in brains of apolipoprotein E deficient mice: augmentation by vitamine E, Brain Res Mol Brain Res, 108, 1, 10.1016/S0169-328X(02)00412-6
Jara Prado, 2003, Homocysteine induced brain lipid peroxydation: effects of NMDA receptor blockade, antioxydant treatment, and nitric oxide synthase inhibition, Neurotox Res, 5, 237, 10.1007/BF03033381
Lee, 2004, Effects of dietary folic acid supplementation on cerebrovascular endothelial dysfunction in rats with induced hyperhomocysteinemia, Brain Res, 996, 139, 10.1016/j.brainres.2003.10.027
Tjiatttas, 2004, Folate deficieny and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation, Aging cell, 3, 71, 10.1111/j.1474-9728.2004.00086.x
Robert, 2005, Regulation of extracellular signal regulated kinase by homocysteine in Hippocampus, Neuroscience, 133, 925, 10.1016/j.neuroscience.2005.03.034
Hasegawa, 2005, Homocysteic acid induces intraneuronal accumulation of neurotoxic Abeat 42: implications for the pathogenesis of Alzheimer's disease, J Neurosc Res, 80, 869, 10.1002/jnr.20514
Baydas, 2005, Metalonin improves learning and memory performances impaired by hyprhomocysteinemia in rats, Brain Res, 1046, 187, 10.1016/j.brainres.2005.04.011
Algaidi Sa, 2005, Long-term homocysteine exposure induces alterations in special learning hippocampal signaling and synaptic plasticity, Exp Neurol, 197, 8, 10.1016/j.expneurol.2005.07.003
Christie, 2005, Enhanced hippocampal long-term potentiation in rats after chronic exposure to homocysteine, Neurosci Lett, 373, 119, 10.1016/j.neulet.2004.09.072
Kim, 2008, Synergistic induction of ER stress by homocysteine and β-amyloid in SH-SY5Y cells, J Nutr Biochem, 19, 754, 10.1016/j.jnutbio.2007.09.009
Kamath, 2006, Elevated levels of homocysteine compromise blood-brain barrier integrity in mice, Blood, 107, 591, 10.1182/blood-2005-06-2506
Pacheco-Quinto, 2006, Homocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta amyloid levels, Neurobiol Dis, 22, 651, 10.1016/j.nbd.2006.01.005
Fuso, 2005, S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beat amylod production, Mol Cell Neurosc, 28, 195, 10.1016/j.mcn.2004.09.007
Lipton, 1997, Neurotoxycity associated with dual ations of homocystéine at the N-methyl-D-aspartate receptor, Proc Natl Acad Sci USA, 94, 5923, 10.1073/pnas.94.11.5923
Klein, 2003, Oxidative stress, cell cycle, and neurodegeneration, J Clin Invest, 111, 785, 10.1172/JCI200318182
Zhang, 1992, L-Homocysteic acid selectivity activates N-methyl-D-aspartate receptors of rat retinal ganglion cells, Neurosc Lett, 139, 173, 10.1016/0304-3940(92)90545-I
Lu, 1999, G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors, Nat Neurosci, 2, 331, 10.1038/7243
Fujii, 2003, Cooperativity between activation of metabotropic glutamate receptors and NMDA receptors in the induction of LTP in hippocampal CA1 neurons, Neurosci Res, 46, 509, 10.1016/S0168-0102(03)00162-7
Poddar, 2009, Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death, J Neurochem, 110, 1095, 10.1111/j.1471-4159.2009.06207.x
Cuenod, 1990, Homocysteic acid as an endogenous excitatory amino acid, Trends Pharmacol Sci, 11, 477, 10.1016/0165-6147(90)90137-W
Kim, 1987, L-homocysteine is a potent neurotoxin on cultures cortical neurons, Brain Res, 437, 103, 10.1016/0006-8993(87)91531-9
Alam, 1998, Plama levels of neuroexcitatory amino acids in patients with migraine or tension headache, J Neurol Sci, 156, 102, 10.1016/S0022-510X(98)00023-9
Zieminska, 2003, Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine evoked acute neurodegeneration of cultures cerebellar granule neurons, Neurochem Int, 43, 481, 10.1016/S0197-0186(03)00038-X
Calvaresi, 2001, B-vitamins, cognition, and aging: a review, J Gerontol B Psychol Sci Soc Sci, 56, 327, 10.1093/geronb/56.6.P327
Finkelstein, 2000, Pathways and regulation of homocysteine metabolism in mammals, Semin Thromb Hemost, 26, 219, 10.1055/s-2000-8466
Palmer, 1979, The mechanism of action of Sadenosylhomocysteinase, J Biol Chem, 254, 1217, 10.1016/S0021-9258(17)34190-X
Finkelstein, 1998, The metabolism of homocysteine: pathways and regulation, Eur J Pediatr, 157, S40, 10.1007/PL00014300
Yi, 2000, Increase in plasma homocysteine associated with parallel increasesin plasma S-adenosylhomocysteiadenosylhomocysteine and lymphocyte DNA hypomethylation, J Biol Chem, 275, 29318, 10.1074/jbc.M002725200
James, 2002, Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology, J Nutr, 132, 2361S, 10.1093/jn/132.8.2361S
Selkeo, 2001, Notch and the genesis and treatment of Alzheimer's disease, Pro Natl Acad Sci USA, 98, 11039, 10.1073/pnas.211352598
Scarpa, 2005, Presenelin 1 gene silencing by S adenosylmethionine/homocysteine: a treatment for Alzheimer disease?, FEBS let, 541, 145, 10.1016/S0014-5793(03)00277-1
Jouvenceau, 2006, Partial inhibition of PP1 alters bidirectional synaptic plasticity in the hippocampus, Eur J Neurosci, 24, 564, 10.1111/j.1460-9568.2006.04938.x
Vafai, 2002, Protein phosphatase 2A methylation: a link beteen elevated plasma homocysteine and Alzheimer's diseae, FEBS Lett, 518, 1, 10.1016/S0014-5793(02)02702-3
Popp, 2009, Homocysteine Metabolism and Cerebrospinal Fluid Markers for Alzheimer's Disease, J Alzheimer's Dis, 18, 819, 10.3233/JAD-2009-1187
Raynaud-Simon, 2004, Nutrition, démences vasculaires et maladie d’Alzheimer, Nutr clin Metabol, 18181
Djukic, 2007, Folate responsive neurologic diseases, Pediatr Neurol, 37, 387, 10.1016/j.pediatrneurol.2007.09.001
Balk, 2007, Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials, Arch Inter Med, 167, 21, 10.1001/archinte.167.1.21
Durga, 2007, Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial, Lancet, 369, 208, 10.1016/S0140-6736(07)60109-3
Aisen, 2008, High dose B vitamin supplementation and cognitive decline in Alzheimer Disease. A randomized controlled trial, JAMA, 300, 1774, 10.1001/jama.300.15.1774
Viswanathan, 2009, Plasma Aβ, homocysteine, and cognition. The Vitamin Intervention for Stroke Prevention (VISP) trial, Neurology, 72, 268, 10.1212/01.wnl.0000339486.63862.db
Wang, 2001, Vitamin B12 and folate in relation to the development of Alzheimer's disease, Neurology, 56, 1188, 10.1212/WNL.56.9.1188
Guist’hau, 2011, Added value of the mediterranean diet: extrapolation to long term enteral nutrition, Nutr Clin Metabol, 25, S7
Gu, 2010, Food combination and Alzheimer disease risk. A protective diet, Arch Neurol, 67, 699, 10.1001/archneurol.2010.84
Sofi, 2009, Evidences on the relationship between Mediterranean diet and health status, Recenti Prog Med, 100, 127