Hfq structure, function and ligand binding

Franze de Fernandez, 1968, Factor fraction required for the synthesis of bacteriophage Qβ-RNA, Nature, 219, 588, 10.1038/219588a0

Franze de Fernandez, 1972, Bacterial proteins required for replication of phage Q ribonucleic acid. Purification and properties of host factor I, a ribonucleic acid binding protein, J Biol Chem, 247, 824, 10.1016/S0021-9258(19)45681-0

Miranda, 1997, Recognition of bacteriophage Qβ plus strand RNA as a template by Qβ replicase: role of RNA interactions mediated by ribosomal protein S1 and host factor, J Mol Biol, 267, 1089, 10.1006/jmbi.1997.0939

Sun, 2002, Predicted structure and phyletic distribution of the RNA-binding protein Hfq, Nucleic Acids Res, 30, 3662, 10.1093/nar/gkf508

Valentin-Hansen, 2004, The bacterial Sm-like protein Hfq: a key player in RNA transactions, Mol Microbiol, 51, 1525, 10.1111/j.1365-2958.2003.03935.x

Møller, 2002, Hfq: a bacterial Sm-like protein that mediates RNA–RNA interaction, Mol Cell, 9, 23, 10.1016/S1097-2765(01)00436-1

Zhang, 2002, The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAs, Mol Cell, 9, 11, 10.1016/S1097-2765(01)00437-3

Vassilieva, 2002, The regulatory role of the Hfq protein in bacterial cells, Mol Biol, 36, 785, 10.1023/A:1021621623503

Senear, 1976, Site-specific interaction of Qβ host factor and ribosomal protein S1 with Qβ and R17 Bacteriophage RNAs, J Biol Chem, 251, 1902, 10.1016/S0021-9258(17)33633-5

de Haseth, 1980, Interaction of Escherichia coli host factor protein with oligoriboadenylates, Biochemistry, 19, 6138, 10.1021/bi00567a029

de Haseth, 1980, Interaction of Escherichia coli host factor protein with Qβ ribonucleic acid, Biochemistry, 19, 6146, 10.1021/bi00567a030

Brescia, 2003, Identification of the Hfq-binding site on DsrA RNA: Hfq binds without altering DsrA secondary structure, RNA, 9, 33, 10.1261/rna.2570803

Moll, 2003, RNA chaperone activity of the Sm-like Hfq protein, EMBO Rep, 4, 284, 10.1038/sj.embor.embor772

Mikulecky, 2004, Escherichia coli Hfq has distinct interaction surfaces for DsrA, rpoS and poly(A) RNAs, Nat Struct Mol Biol, 11, 1206, 10.1038/nsmb858

Sun, 2006, Escherichia coli Hfq binds A18 and DsrA Domain II with similar 2:1 Hfq6/RNA stoichiometry using different surface sites, Biochemistry, 45, 4875, 10.1021/bi0523613

Azam, 1999, Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity, J Biol Chem, 274, 33105, 10.1074/jbc.274.46.33105

Schumacher, 2002, Structures of the pleiotropic translational regulator Hfq and an Hfq–RNA complex: a bacterial Sm-like protein, EMBO J, 21, 3546, 10.1093/emboj/cdf322

Tsui, 1994, Characterization of broadly pleiotropic phenotypes caused by an insertion mutation in Escherichia coli K-12, Mol Microbiol, 13, 35, 10.1111/j.1365-2958.1994.tb00400.x

Brown, 1996, Efficient translation of the RpoS sigma factor in Salmonella typhimurium requires Host Factor I, an RNA-binding protein encoded by the hfq gene, J Bacteriol, 178, 3763, 10.1128/jb.178.13.3763-3770.1996

Muffler, 1996, The RNA-binding protein HF-I, known as host factor for phage Qβ RNA replication, is essential for rpoS translation in Escherichia coli, Genes Dev, 10, 1143, 10.1101/gad.10.9.1143

Muffler, 1997, The RNA-binding protein HF-I plays a global regulatory role, which is largely, but not exclusively, due to its role in expression of the sigmaS subunit of RNA polymerase in Escherichia coli, J Bacteriol, 179, 297, 10.1128/jb.179.1.297-300.1997

Storz, 2004, Controlling mRNA stability and translation with small, noncoding RNAs, Curr Opin Microbiol, 7, 140, 10.1016/j.mib.2004.02.015

Majdalani, 2005, Bacterial small RNA regulators, Crit Rev Biochem Mol Biol, 40, 93, 10.1080/10409230590918702

Livny, 2007, Identification of small RNAs in diverse bacterial species, Curr Opin Microbiol, 10, 96, 10.1016/j.mib.2007.03.005

Gottesman, 2004, The small RNA regulators of Escherichia coli: roles and mechanisms, Annu Rev Microbiol, 58, 303, 10.1146/annurev.micro.58.030603.123841

Storz, 2005, An abundance of RNA regulators, Annu Rev Biochem, 74, 199, 10.1146/annurev.biochem.74.082803.133136

Geissmann, 2004, Hfq, a new chaperoning role: binding to messenger RNA determines access for small RNA regulator, EMBO J, 23, 396, 10.1038/sj.emboj.7600058

Lease, 2004, Cycling of the Sm-like protein Hfq on the DsrA small regulatory RNA, J Mol Biol, 344, 1211, 10.1016/j.jmb.2004.10.006

Afonyushkin, 2005, Both RNase E and RNase III control the stability of sodB mRNA upon translational inhibition by the small regulatory RNA RyhB, Nucleic Acids Res, 33, 1678, 10.1093/nar/gki313

Hajnsdorf, 2000, Host factor Hfq of Escherichia coli stimulates elongation of poly(A) tails by poly(A) polymerase I, Proc Natl Acad Sci USA, 97, 1501, 10.1073/pnas.040549897

Mohanty, 2004, The Sm-like protein Hfq regulates polyadenylation dependent mRNA decay in Escherichia coli, Mol Microbiol, 54, 905, 10.1111/j.1365-2958.2004.04337.x

Folichon, 2003, The poly(A) binding protein Hfq protects RNA from RNase E and exoribonucleolytic degradation, Nucleic Acids Res, 31, 7302, 10.1093/nar/gkg915

Folichon, 2005, Simulation of poly(A) synthesis by Escherichia coli poly(A)polymerase I is correlated with Hfq binding to poly(A) tails, FEBS J, 272, 454, 10.1111/j.1742-4658.2004.04485.x

Vytvytska, 2000, Hfq (HF1) stimulates ompA mRNA decay by interfering with ribosome binding, Genes Dev, 14, 1109, 10.1101/gad.14.9.1109

Valentin-Hansen, 2007, Small RNAs controlling outer membrane porins, Curr Opin Microbiol, 10, 152, 10.1016/j.mib.2007.03.001

Večerek, 2005, Translational autocontrol of the Escherichia coli hfq RNA chaperone gene, RNA, 11, 976, 10.1261/rna.2360205

Sonnleitner, 2004, Functional effects of variants of the RNA chaperone Hfq, Biochem Biophys Res Commun, 323, 1017, 10.1016/j.bbrc.2004.08.190

Ziolkowska, 2006, Hfq variant with altered RNA binding functions, Nucleic Acids Res, 34, 709, 10.1093/nar/gkj464

Sauter, 2003, Sm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coli, Nucleic Acids Res, 31, 4091, 10.1093/nar/gkg480

Nikulin, 2005, Structure of Pseudomonas aeruginosa Hfq protein, Acta Crystallogr D Biol Crystallogr, 61, 141, 10.1107/S0907444904030008

Wilusz, 2005, Eukaryotic Lsm proteins: lessons from bacteria, Nat Struct Mol Biol, 12, 1031, 10.1038/nsmb1037

Séraphin, 1995, Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs, EMBO J, 14, 2089, 10.1002/j.1460-2075.1995.tb07200.x

Arluison, 2002, Structural modelling of the Sm-like protein Hfq from Escherichia coli, J Mol Biol, 320, 705, 10.1016/S0022-2836(02)00548-X

Sukhodolets, 2003, Interaction of Escherichia coli RNA polymerase with the ribosomal protein S1 and the Sm-like ATPase Hfq, Biochemistry, 42, 8022, 10.1021/bi020638i

Thore, 2003, Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA: common features of RNA binding in archaea and eukarya, J Biol Chem, 278, 1239, 10.1074/jbc.M207685200

Stark, 2001, Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle, Nature, 409, 539, 10.1038/35054102

Tolstorukov, 2005, A-tract clusters may facilitate DNA packaging in bacterial nucleoid, Nucleic Acids Res, 33, 3907, 10.1093/nar/gki699

Arluison, 2007, Spectroscopic observation of RNA chaperone activities of Hfq in post-transcriptional regulation by a small non-coding RNA, Nucleic Acids Research, 10.1093/nar/gkl1124

Morita, 2005, RNase E-based ribonucleoprotein complexes: mechanical basis of mRNA destabilization mediated by bacterial noncoding RNAs, Genes Dev, 19, 2176, 10.1101/gad.1330405

Morita, 2006, Translational repression is sufficient for gene silencing by bacterial small non coding RNAs in the absence of mRNA destruction, Proc Natl Acad Sci USA, 103, 4858, 10.1073/pnas.0509638103

Morita, 2004, Enolase in the RNA degradosome plays a crucial role in the rapid decay of glucose transporter mRNA in the response to phophosugar stress in Escherichia coli, Mol Microbiol, 54, 1063, 10.1111/j.1365-2958.2004.04329.x

Massé, 2003, Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli, Genes Dev, 17, 2374, 10.1101/gad.1127103

Arluison, 2005, Three-dimensional structures of fibrillar Sm Proteins: Hfq and other Sm-like proteins, J Mol Biol, 356, 86, 10.1016/j.jmb.2005.11.010

Mura, 2003, The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs), Protein Sci, 12, 832, 10.1110/ps.0224703

Huntzinger, 2005, Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression, EMBO J, 24, 824, 10.1038/sj.emboj.7600572

Recsei, 1986, Regulation of exoprotein gene expression by agr, Mol Gen Genet, 202, 58, 10.1007/BF00330517

Geisinger, 2006, Inhibition of rot translation by RNAIII, a key feature of agr function, Mol Microbiol, 61, 1038, 10.1111/j.1365-2958.2006.05292.x