Guidelines for the use and interpretation of assays for monitoring autophagy

Autophagy - Tập 8 Số 4 - Trang 445-544 - 2012
Daniel J. Klionsky1, Fábio Camargo Abdalla, Hagai Abeliovich2, Robert T. Abraham, Abraham Acevedo‐Arozena, Khosrow Adeli, Lotta Agholme, Maria Agnello3,4, Patrizia Agostinis5, Julio A. Aguirre‐Ghiso, Hyung Jun Ahn, Ouardia Aït-Mohamed, Slimane Ait‐Si‐Ali6, Takahiko Akematsu, Shizuo Akira7, Hesham M. Al‐Younes, Munir A. Al‐Zeer, Matthew L. Albert8, Roger L. Albin, Javier Alegre‐Abarrategui, Maria Francesca Aleo, Mehrdad Alirezaei, Alexandru Almasan, Maylin Almonte‐Becerril, Atsuo Amano9, Ravi K. Amaravadi, Shoba Amarnath, Amal O. Amer, Nathalie Andrieu‐Abadie, Vellareddy Anantharam, David K. Ann3,4, Shailendra Anoopkumar‐Dukie, Hiroshi Aoki3,4, Nadezda Apostolova, Giuseppe Arancia, John P. Aris, Katsuhiko Asanuma10, Nana Asare, Hisashi Ashida, Valerie Askanas11, David S. Askew12, Patrick Auberger3,4, Misuzu Baba13, Steven K. Backues, Eric H. Baehrecke14, Ben A. Bahr15, Xue-Yuan Bai, Yannick Bailly16, Robert A. Baiocchi17, Giulia Baldini, Walter Balduini18, Andrea Ballabio19,20,21,22, Bruce A. Bamber23, Edward T. W. Bampton, Gábor Juhász, Clinton R. Bartholomew, Diane C. Bassham24, Robert C. Bast17, Henri Batoko, Boon-Huat Bay, Isabelle Beau25, Daniel Béchet, Thomas J. Begley, Christian Behl26, Christian Behrends26, Soumeya Bekri, Bryan H. Bellaire, Linda J. Bendall, Luca Benetti3,4, Laura Berliocchi3,4, Henri Bernardi, Francesca Bernassola3,4, Sébastien Besteiro27, Ingrid Bhatia-Kissova28, Xiaoning Bi29, Martine Biard-Piechaczyk30, Janice S. Blum31, Lawrence Boise, Paolo Bonaldo, David L. Boone, Beat Bornhäuser, Karina Ramalho Bortoluci, Ioannis Bossis, Frédéric Bost, Jean‐Pierre Bourquin, Patricia Boya32, Michaël Boyer‐Guittaut33, Peter V. Bozhkov, Nathan Brady, Claudio Brancolini3,4, Andreas Brech, Jay E. Brenman, Ana Brennand3,4, Emery Bresnick, Patrick Brest34,35, Dave Bridges, Molly L. Bristol, Paul S. Brookes, Karen Brown, John H. Brumell9, Nicola Brunetti‐Pierri, Ulf T. Brunk36, Dennis E. Bulman, Scott J. Bultman, Geert Bultynck5, Lena F. Burbulla, Wilfried Bursch37, Jonathan P. Butchar, Wanda Buzgariu, Sérgio Paulo Bydlowski, Ken Cadwell9, Monika Cahová, Jingjing Cai38, Jiyang Cai, Qian Cai, Bruno Calabretta, Javier Calvo‐Garrido39, Nadine Camougrand28, Michelangelo Campanella, Jenny Campos‐Salinas, Eleonora Candi, Lizhi Cao, Allan B. Caplan, Simon R. Carding, Sandra M. Cardoso, Jennifer S. Carew, Cathleen R. Carlin, Virginie Carmignac, Leticia A.M. Carneiro, Serena Carra, Rosario A. Caruso, Giorgio Casari, Caty Casas40, Roberta Castino3,4, Eduardo Cebollero41, Francesco Cecconi42, Jean Celli, Hassan Chaachouay, Han‐Jung Chae43,44, Chee‐Yin Chai, Min Chen45, Edmond Y.W. Chan45, Raymond Chuen‐Chung Chang, Chi‐Ming Che46, Ching‐Chow Chen3,4, Guang‐Chao Chen3,4, Guo-Qiang Chen3,4, Quan Chen3,4, Steve S.-L. Chen3,4, Wen‐Li Chen47, Hao Chen3,4, Xiangmei Chen3,4, Xiequn Chen3,4, Ye-Guang Chen3,4, Yingyu Chen48, Yongqiang Chen3,4, Yu-Jen Chen3,4, Zhixiang Chen3,4, Alan Cheng3,4, Christopher H.K. Cheng3,4, Yan Cheng3,4, Heesun Cheong, Jae‐Ho Cheong, Sara Cherry, Russ Chess‐Williams3,4, Zelda H. Cheung, Éric Chevet49, Hui-Ling Chiang, Roberto Chiarelli, Tomoki Chiba, Lih‐Shen Chin50, Shih‐Hwa Chiou, Francis V. Chisari, Chi Hin Cho3,4, Dong-Hyung Cho3,4, Augustine M.K. Choi51, DooSeok Choi51, Kyeong Sook Choi51, Mary E. Choi51, Salem Chouaib52, Vinay Choubey, Charleen T. Chu43,44, Tsung-Hsien Chuang, Sheau‐Huei Chueh, Taehoon Chun43,44, Yong-Joon Chwae, Mee‐Len Chye, Roberto Ciarcia, Maria Rosa Ciriolo53, Michael J. Clague, Robert Clark3,4, Robert Clarke54, Patrice Codogno25, Hilary A. Coller, María I. Colombo3,4, Sergio Comincini, Maria Condello3,4, Fabrizio Condorelli, Mark Cookson, Graham H. Coombs55, Isabelle Coppens, Ramón Corbalán41, Pascale Cossart56, Paola Costelli57, Safia Costes58, Ana Coto‐Montes3,4, Eduardo Couve59, Fraser P. Coxon, James M. Cregg3,4, José L. Crespo, Marianne J. Cronjé, Ana María Cuervo3,4, Joseph J. Cullen, Mark J. Czaja, Marcello D’Amelio42, Arlette Darfeuille-Michaud, Lester M. Davids3,4, Faith E. Davies60, Massimo De Felici, John F. de Groot, Cornelis A. M. de Haan, Maria Antonietta De Matteis, Angelo De Milito, Daniela De Zio, Jayanta Debnath3,4, Alexei Degterev3,4, Benjamin Dehay61, Lea M.D. Delbridge, Francesca Demarchi3,4, Yi Deng, Jörn Dengjel, Paul Dent62, Donna Denton, Vojo Deretić63, Shyamal D. Desai, Rodney J. Devenish3,4, Mario Di Gioacchino, Gilbert Di Paolo, Chiara Di Pietro, Inés Dı́az-Laviada64, María T. Díaz‐Meco65, Javier Díaz‐Nido, Ivan Ðikić, Savithramma P. Dinesh-Kumar3,4, Wen-Xing Ding, C W Distelhorst3,4, Abhinav Diwan, Mojgan Djavaheri‐Mergny25, Svetlana Dokudovskaya66, Zheng Dong3,4, Frank C. Dorsey67, Victor Dosenko, James J. Dowling, Stephen Doxsey, Marlène Dreux68, Mark E. Drew3,4, Qiuhong Duan, Michel A. Duchosal3,4, Karen Duff, Isabelle Dugail, Madeleine Durbeej, Michael Duszenko3,4, Charles L. Edelstein, Aimee L. Edinger, Gustavo Egea, Ludwig Eichinger, N. Tony Eissa3,4, Sühendan Ekmekçioglu, Wafik S. El‐Deiry, Zvulun Elazar3,4, Mohamed Elgendy, Lisa M. Ellerby, Kai Er Eng3,4, Anna‐Mart Engelbrecht, Simone Engelender3,4, Rajaraman Eri, Ricardo Escalante69, Audrey Esclatine70,71, Eeva‐Liisa Eskelinen3,4, Lucile Espert30, Virginia Espina, Huizhou Fan, Jia Fan3,4, Qi-Wen Fan, Zhen Fan3,4, Shengyun Fang, Yongqi Fang, Manolis Fanto72, Alessandro Fanzani73, Thomas Farkas3,4, Jean‐Claude Farré, Mathias Faure74, Marcus Fechheimer, Carl G. Feng, Jian Feng75, Qili Feng, Youji Feng, László Fésüs76, Ralph Feuer3,4, Maria E. Figueiredo‐Pereira, Gian María Fimia42, Diane C. Fingar, Steven Finkbeiner54, Toren Finkel, Kim D. Finley3,4, Filomena Fiorito, Edward A. Fisher, Paul B. Fisher, Marc Flajolet3,4, Maria L. Florez‐McClure, Salvatore Florio, Edward A. Fon77, Francesco Fornai78, Franco Fortunato, Rati Fotedar, Daniel H. Fowler, Howard S. Fox, Rodrigo Franco, Lisa B. Frankel, Marc Fransen3,4, José M. Fuentes3,4, Juàn Fueyo3,4, Jun Fujii3,4, Kozo Fujisaki3,4, Eriko Fujita, Mitsunori Fukuda79, Ruth H. Furukawa, Matthias Gaestel, Philippe Gailly, Małgorzata Gajewska, Brigitte Galliot3,4, Vincent Galy80,81, Subramaniam Ganesh, Barry Ganetzky, Ian G. Ganley3,4, Fen‐Biao Gao3,4, G Gao3,4, Jinming Gao3,4, Lorena Garcia, Guillermo Garcia-Manero, Mikel Garcia‐Marcos, Marjan Garmyn, Andrei L. Gartel, Evelina Gatti, Mathias Gautel, Thomas R. Gawriluk, Matthew E. Gegg, Jiefei Geng, Marc Germain82, Jason E. Gestwicki, David A. Gewirtz3,4, Saeid Ghavami, Pradipta Ghosh, A M Giammarioli, Alexandra N. Giatromanolaki, Spencer B. Gibson3,4, Robert W. Gilkerson, Michael L. Ginger3,4, Henry N. Ginsberg, Jakub Gołąb, Michael S. Goligorsky, Pierre Golstein83,84, Candelaria Gómez-Manzano, Ebru Göncü, Céline Gongora85, Claudio González3,4, Ramón González41, Cristina González‐Estévez3,4, Rosa A. González‐Polo, Elena González‐Rey, Nikolai V. Gorbunov, Sharon M. Gorski3,4, Sandro Goruppi, Roberta A. Gottlieb3,4, Devrim Gözüaçık, Giovanna Elvira Granato, Gary Grant, Kim N. Green, Ales Gregorc, Frédéric Gros86,87, Charles Grose, Thomas W. Grunt, Philippe Gual88,89, Jun‐Lin Guan, Kun‐Liang Guan, Sylvie M. Guichard, Anna S. Gukovskaya, Ilya Gukovsky, Jan Gunst90, Åsa B. Gustafsson, Andrew J. Halayko, Amber N. Hale, Sandra K. Halonen, Maho Hamasaki, Feng Han3,4, Ting Han3,4, Michael K. Hancock, Malene Hansen3,4, Hisashi Harada, Masaru Harada91, Stefan E. Hardt, J. Wade Harper, Adrian L. Harris92, James Harris93, Steven D. Harris, Makoto Hashimoto, Jeffrey A. Haspel3,4, Shin-ichiro Hayashi, Lori A. Hazelhurst, Congcong He3,4, You‐Wen He3,4, Marie‐Josée Hebert, Kim A. Heidenreich3,4, Miep Helfrich, G. Vignir Helgason, Elizabeth P. Henske, Brian Herman94, Paul K. Herman, Claudio Hetz3,4, Sabine Hilfiker, Joseph A. Hill3,4, Lynne J. Hocking, Paul Hofman95, Thomas G. Hofmann, Jörg Höhfeld, Tessa L. Holyoake, Ming‐Huang Hong3,4, David A. Hood3,4, Gökhan S. Hotamisligil, Ewout J. Houwerzijl, Maria Høyer-Hansen3,4, Bingren Hu3,4, Chien‐An Andy Hu3,4, Hong‐Ming Hu3,4, Ya Hua3,4, Canhua Huang3,4, Ju Huang3,4, Shengbing Huang3,4, Wei‐Pang Huang3,4, Tobias B. Huber, Won-Ki Huh, Tai‐Ho Hung43,44, Ted R. Hupp, Gang Min Hur, James B. Hurley, Sabah N.A. Hussain, Patrick J. Hussey, Seungmin Hwang, Atsuhiro Ichihara, Shirin Ilkhanizadeh, Ken Inoki9, Takeshi Into3,4, Valentina Iovane, Juan Iovanna, Nancy Y. Ip96, Yoshitaka Isaka3,4, H. Ishida, Ciro Isidoro, K Isobe, Akiko Iwasaki3,4, Marta Izquierdo, Yotaro Izumi, Panu Jaakkola, Marja Jäättelä97, George R. Jackson3,4, William T. Jackson3,4, Bassam Janji98, Marina Jendrach, Ju‐Hong Jeon, Eui-Bae Jeung, Hong Jiang3,4, Liwen Jiang3,4, Jean X. Jiang3,4, Ming Jiang99, Qing Jiang3,4, Xuejun Jiang3,4, Alberto Jiménez, Meiyan Jin3,4, Shengkan Jin3,4, Cheol O. Joe, Terje Johansen3,4, Daniel E. Johnson, Gail V.W. Johnson, Nicola L. Jones, Bertrand Joseph3,4, Suresh K. Joseph3,4, Annie M. Joubert, Gábor Juhász, Lucienne Juillerat-Jeanneret, Chang Hwa Jung100, Yong‐Keun Jung100, Kai Kaarniranta3,4, Allen Kaasik, Tomohiro Kabuta, Motoni Kadowaki101, Katarina Kågedal, Yoshiaki Kamada, Vitaliy O. Kaminskyy, Harm H. Kampinga102, Hiromitsu Kanamori, Chanhee Kang45, Khong Bee Kang45, Kwang Il Kang45, Rui Kang45, Yoon-A Kang45, Tomotake Kanki, Thirumala‐Devi Kanneganti, Haruo Kanno, Anumantha G. Kanthasamy, Arthi Kanthasamy, Vassiliki Karantza, Gur P. Kaushal, Susmita Kaushik, Yoshinori Kawazoe, Po‐Yuan Ke3,4, John H. Kehrl, Ameeta Kelekar103, Claus Kerkhoff, David Kessel104, Hany Khalil, Jan A.K.W. Kiel90, Amy A. Kiger, Akio Kihara, Do‐Hyung Kim105, Dong‐Hou Kim105, Eun‐Kyoung Kim105, Hyung‐Ryong Kim105, Jeong Hun Kim105, Jin Cheon Kim105, John K. Kim105, Peter K. Kim105, Seong Who Kim105, Yonghyun Kim105, Adi Kimchi106, Alec Kimmelman, Jason King, Timothy J. Kinsella107, Vladimir Kirkin108, Zhi‐Gang She, Katsuhiko Kitamoto10, Kaio Kitazato, Ludger Klein109, Walter T. Klimecki, Jochen Klucken, Erwin Knecht110, Ben C.B. Ko3,4, Jan Christoph Koch, Rejko Krueger3,4, Jae‐Young Koh, Young Ho Koh, Masato Koike, Masaaki Komatsu111, Eiki Kominami112, Hee Jeong Kong, Wei-Jia Kong, Viktor I. Korolchuk, Yaichiro Kotake3,4, Michael I. Koukourakis, Juan Kourí, Attila L. Kovács3,4, Claudine Kraft, Dimitri Krainc, Helmut Krämer113, Carole Kretz‐Remy114, Anna M. Krichevsky, Guido Kroemer115,116,117,118,119, Rejko Krüger120, Oleg Krut, Nicholas T. Ktistakis3,4, Chia-Yi Kuan121, Róża Kucharczyk28, Ashok Kumar122,123,124,125, Raj Kumar3,4, Sharad Kumar126, Mondira Kundu3,4, Hsing‐Jien Kung, Tino Kurz, Ho Jeong Kwon, Albert R. La Spada, Frank Lafont67, Trond Lamark, Jacques Landry3,4, Jon D. Lane, Pierre Lapaquette83,84, Jocelyn Laporte3,4, Lajos László3,4, Sergio Lavandero64,127, Josée Lavoie, Robert Layfield3,4, Pedro A. Lazo, Weidong Le3,4, Laurent Le Cam128,85, Daniel J. Ledbetter, Alvin Lee129, Byung‐Wan Lee129, Gyun Min Lee129, Jong‐Dae Lee129, Ju‐Hyun Lee129, Michael Lee129, Myung‐Shik Lee129, Sung Sik Lee129, Christiaan Leeuwenburgh, Patrick Legembre130, Renaud Legouis71,131, Michael H. Lehmann3,4, Huan‐Yao Lei132, Qun‐Ying Lei3,4, David A. Leib3,4, J. Leiro36, John J. Lemasters, Antoinette Lemoine133, Maciej S. Lesniak, Dina Lev3,4, Victor Levenson, Beth Levine134,135, Efrat Levy, Faqiang Li3,4, Junlin Li3,4, Lian Li3,4, Sheng Li3,4, Weijie Li3,4, Xuejun Li3,4, Yan-Bo Li3,4, Yi-Ping Li3,4, Chengyu Liang, Qiangrong Liang, Yung-Feng Liao, Pawel P. Liberski, Andrew P. Lieberman3,4, Hyunjung J. Lim23, Kah‐Leong Lim136,137, Kyu Lim23, Chiou‐Feng Lin3,4, Fu‐Cheng Lin3,4, Jian Lin3,4, Jiandie D. Lin3,4, Kwang‐Huei Lin3,4, Wan‐Wan Lin3,4, Weei-Chin Lin3,4, Yi‐Ling Lin3,4, Rafael Linden, Paul Lingor3,4, Jennifer Lippincott-Schwartz, Michael P. Lisanti, Paloma B. Liton, Bo Liu3,4, Chun-Feng Liu3,4, Kaiyu Liu138,139, Leyuan Liu3,4, Qiong Liu3,4, Wei Liu3,4, Young‐Chau Liu3,4, Yule Liu3,4, Richard A. Lockshin, Chun‐Nam Lok, Sagar Lonial140, Ben Loos, Gabriel López-Berestein141, Carlos López‐Otín142, Laura Lossi3,4, Michael T. Lotze3,4, Péter Lőw143, Binfeng Lu3,4, Bingwei Lu3,4, Jiahong Lu144, Zhen Lü3,4, Frédéric Luciano145,35, Nicholas W. Lukacs, Anders H. Lund, Melinda A. Lynch-Day, Yong Ma146, Fernando Macián, Jeff P. MacKeigan, Kay F. Macleod31, Frank Madeo147, Luigi Maiuri148, Maria Chiara Maiuri149,118, Davide Malagoli, May Christine V. Malicdan, Walter Malorni150, Na Man3,4, Eva‐Maria Mandelkow, Stéphen Manon28, Irena Manov3,4, Kai Mao3,4, Xiang Mao3,4, Zixu Mao, Philippe Marambaud151, Daniela Marazziti, Yves L. Marcel, Katie Marchbank, Piero Marchetti, Stefan J. Marciniak, Mateus Marcondes, Mohsen Mardi, Gabriella Marfè, Guillermo Mariño32, Maria Markaki152, Mark R. Marten, Séamus J. Martin3,4, Camille Martinand-Mari153, Wim Martinet3,4, Marta Martínez‐Vicente, Matilde Masini, Paola Matarrese, Saburo Matsuo9, Rafaele Matteoni, Andreas Mayer, Nathalie M. Mazure154, David J. McConkey, Melanie J. McConnell, Catherine McDermott, Christine McDonald, Gerald M. McInerney, Sharon L. McKenna, BethAnn McLaughlin155,156,157, Pamela J. McLean, Christopher R. McMaster, G. Angus McQuibban, Alfred J. Meijer37, Miriam H. Meisler, Alicia Meléndez158, Thomas J. Melia159, Sonia Melino, María A. Mena3,4, Javier A. Menéndez, Rubem F. S. Menna‐Barreto, Manoj B. Menon, Fiona M. Menzies, Carol A. Mercer, Adalberto Merighi, Diane E. Merry, Stefania Meschini, Christian G. Meyer, Thomas F. Meyer, Chao‐Yu Miao, Jun‐Ying Miao, Paul A.M. Michels3,4, Carine Michiels, Dalibor Mijaljica, Rosario Moratalla3,4, Saverio Minucci, Clelia Miracco160, Cindy K. Miranti, Ioannis Mitroulis, Keisuke Miyazawa, Noboru Mizushima161, Baharia Mograbi34,35, Simin Mohseni, Xavier Molero, Bertrand Mollereau, Faustino Mollinedo, Takashi Momoi3,4, Iryna Monastyrska129, Martha M. Monick, Mervyn J. Monteiro, Michael N. Moore43,44, Rodrigo Mora, Kevin Moreau3,4, Paula I. Moreira143, Yuji Moriyasu17, Jorge Moscat65, Serge Mostowy, Jeremy C. Mottram, T. Motyl54, Charbel Moussa, Sylke Müller, Sylviane Muller86, Karl Münger162, Christian Münz26, Leon O. Murphy3,4, Maureen E. Murphy3,4, Antonio Musarò, Indira Mysorekar, Eiichiro Nagata3,4, Kazuhiro Nagata, Aimable Nahimana, Usha Nair, Toshiyuki Nakagawa, Kiichi Nakahira, Hiroyasu Nakano, Hitoshi Nakatogawa, Meera Nanjundan, Naweed I. Naqvi3,4, Derek P. Narendra, Masashi Narita, Miguel Navarro, Steffan T. Nawrocki, Taras Y. Nazarko, Andriy Nemchenko, Mihai G. Netea, Thomas P. Neufeld3,4, Paul A. Ney3,4, Ioannis P. Nezis, Huu Phuc Nguyen, Daotai Nie163, Ichizo Nishino3,4, Corey Nislow, Ralph A. Nixon3,4, Takeshi Noda3,4, Angelika A. Noegel, Anna Nogalska164, S. Noguchi, Lucia Notterpek, Ivana Novak165, Tomoyoshi Nozaki, Nobuyuki Nukina, Thorsten Nürnberger, Beat Nyfeler, Keisuke Obara, Terry D. Oberley, Salvatore Oddo, Michinaga Ogawa3,4, Toya Ohashi, Koji Okamoto, Nancy L. Oleinick3,4, F. Javier Oliver, Laura J. Olsen3,4, Stefan Olsson, Onya Opota, Timothy F. Osborne, Gary K. Ostrander, Kinya Otsu3,4, Jing-hsiung James Ou3,4, Mireille Ouimet, Michael Overholtzer3,4, Bülent Özpolat3,4, Paolo Paganetti, Ugo Pagnini, Nicolas Pallet, Glen E. Palmer3,4, Camilla Palumbo, Tianhong Pan3,4, Theocharis Panaretakis, Udai Bhan Pandey, Zuzana Papáčková, Issidora S. Papassideri166, Irmgard Paris, Junsoo Park3,4, Ohkmae K. Park3,4, Jan B. Parys5, Katherine R. Parzych, Susann Patschan, Cam Patterson158, Sophie Pattingre85, John M. Pawelek, Jianxin Peng, David H. Perlmutter3,4, Ida Perrotta3,4, George Perry167,168, Shazib Pervaiz169, Matthias Peter170, Godefridus J. Peters, Morten Petersen, Goran Petrovski, James M. Phang, Mauro Piacentini171, Philippe Pierre, Valérie Pierrefite‐Carle11, Gérard Pierron, Ronit Pinkas-Kramarski3,4, Antonio Piras, Natik Piri, Leonidas C. Platanias, Stefanie Pöggeler, Marc Poirot3,4, Angelo Poletti, Christian Poüs172,173, Mercedes Pozuelo-Rubio174, Mette Prætorius-Ibba, Anil Prasad, Mark Prescott3,4, Muriel Priault28, Nathalie Produit-Zengaffinen, Ann Progulske‐Fox3,4, Tassula Proikas‐Cezanne175, Serge Przedborski176,177,178, Karin Przyklenk, Rosa Puertollano3,4, Julien Puyal179,180, Shu‐Bing Qian, Liang Qin, Zheng-Hong Qin, Susan E. Quaggin, Nina Raben3,4, Hannah Rabinowich, Simon W. Rabkin, Irfan Rahman, Abdelhaq Rami3,4, Georg Ramm3,4, Glenn Randall, Felix Randow, V. Ashutosh Rao3,4, Jeffrey C. Rathmell, Brinda Ravikumar, Swapan K. Ray3,4, Bruce H. Reed, John C. Reed67, Fulvio Reggiori181, Jean-Claude Régnier3,4, Andreas S. Reichert, John J. Reiners, Rüssel J. Reiter, Jun Ren3,4, José Luis Revuelta, Christopher J. Rhodes, Konstantinos Ritis, Elizete Rizzo, Jeffrey Robbins3,4, Michel Roberge3,4, Hernán Roca, Maria Carmela Roccheri3,4, Stéphane Rocchi182, H. Peter Rodemann, Santiago Rodrı́guez de Córdoba, Bärbel Rohrer3,4, Igor B. Roninson, Kirill V. Rosen183, Magdalena Rost–Roszkowska, Mustapha Rouis184, Kasper M.A. Rouschop, Francesca Rovetta3,4, Brian P. Rubin3,4, David C. Rubinsztein185, Klaus Ruckdeschel, Edmund B. Rucker, Assaf Rudich, Emil Rudolf, Nelson Ruiz‐Opazo, Rossella Russo, Tor Erik Rusten, Kevin M. Ryan186, Stefan W. Ryter, David M. Sabatini, Junichi Sadoshima3,4, Tapas Saha, Tatsuya Saitoh, Hiroshi Sakagami3,4, Yasuyoshi Sakai3,4, Ghasem Hosseini Salekdeh, Paolo Salomoni, Paul M. Salvaterra3,4, Guy Salvesen, Rosa Salvioli3,4, Anthony M. J. Sanchez187, José A. Sánchez‐Alcázar36, Ricardo Sánchez‐Prieto, Marco Sandri188, Uma Sankar3,4, Poonam Sansanwal, Laura Santambrogio3,4, Shweta Saran, Sovan Sarkar, Minnie Sarwal, Chihiro Sasakawa3,4, Aušra Sasnauskienė, Miklós Sass3,4, Miyuki Sato9, Anthony H.V. Schapira, Michael Scharl3,4, Hermann Schätzl, Wiep Scheper189, Stefano Schiaffino, Claudio Schneider3,4, Marion E. Schneider3,4, Regine Schneider‐Stock190,191, Patricia V. Schoenlein, Daniel F. Schorderet192,193,194, Christoph Schüller, Gary K. Schwartz, Luca Scorrano195, Linda Sealy, Per O. Seglen, Juan Segura‐Aguilar196, Iban Seiliez, Oleksandr Seleverstov3,4, Christian Sell3,4, Jong Bok Seo, Duška Šeparović, Vijayasaradhi Setaluri, Takao Setoguchi, Carmine Settembre, John J. Shacka3,4, Mala Shanmugam, Irving M. Shapiro3,4, Eitan Shaulian3,4, Reuben J. Shaw, James H. Shelhamer, Han‐Ming Shen3,4, Wei‐Chiang Shen3,4, Zu-Hang Sheng3,4, Yang Shi197, Kenichi Shibuya, Yoshihiro Shidoji, Jeng‐Jer Shieh, Chwen‐Ming Shih3,4, Yohta Shimada, Shigeomi Shimizu, Takahiro Shintani, Orian Shirihai, Gordon C. Shore, Andriy А. Sibirny, Stan B. Sidhu198,199, Beata Sikorska, Elaine C.M. Silva-Zacarin3,4, Alison Simmons200, Anna Katharina Simon3,4, Hans-Uwe Símon201, Cristiano Simone3,4, Anne Simonsen3,4, David Sinclair3,4, Rajat Singh, Debasish Sinha, Frank A. Sinicrope67, Agnieszka Sirko, Parco M. Siu, Panagiotis Skendros, Vojtěch Škop, Vladimir P. Skulachev, Ruth S. Slack, Soraya S. Smaili, Duncan R. Smith3,4, Marı́a S. Soengas, Thierry Soldati202, Xueqin Song, Anil K. Sood, Tuck Wah Soong, Federica Sotgia203,204, Stephen A. Spector, Claudia Spies, Wolfdieter Springer, Srinivasa M. Srinivasula, Leonidas Stefanis, Joan S. Steffan, Ruediger Stendel, Harald Stenmark3,4, Anastasis Stephanou, Stęphan T. Stern, Cinthya Sternberg, Björn Stork, Peter Strålfors205, Carlos S. Subauste3,4, Xinbing Sui, David Sulzer3,4, Jun Sun, Shi‐Yong Sun, Zhi-Jun Sun3,4, Joseph J.�Y. Sung, Naoki Suzuki3,4, Toshihiko Suzuki3,4, Michele S. Swanson3,4, Charles Swanton206,99, Sean T. Sweeney207, Lai‐King Sy3,4, György Szabadkai208, Ira Tabas3,4, Heinrich Taegtmeyer, Marco Tafani3,4, Krisztina Takács‐Vellai, Yoshitaka Takano, Kaoru Takegawa, Genzou Takemura, Fumihiko Takeshita3,4, Nicholas J. Talbot3,4, Kevin S. W. Tan209, Keiji Tanaka3,4, Kozo Tanaka3,4, Daolin Tang, Dingzhong Tang, Isei Tanida3,4, Bakhos A. Tannous, Nektarios Tavernarakis152, Graham S. Taylor3,4, Gregory A. Taylor3,4, J. Paul Taylor3,4, Lance S. Terada, Alexei Terman3,4, Gianluca Tettamanti3,4, Karin Thevissen210, Craig B. Thompson211, Andrew Thorburn3,4, Michael Thumm3,4, Fengfeng Tian3,4, Yuan Tian3,4, Glauco Tocchini-Valentini, Aviva M. Tolkovsky3,4, Yasuhiko Tomino, Lars Tönges, Sharon A. Tooze3,4, Cathy Tournier, John Tower3,4, Roberto Towns, Vladimir Trajkovič, Leonardo H. Travassos212,213, Ting‐Fen Tsai, Mario P. Tschan, Takeshi Tsubata3,4, Allan Tsung, Boris Turk, Lorianne S. Turner, Suresh C. Tyagi, Yasuo Uchiyama3,4, Takashi Ueno3,4, Midori Umekawa, Rika Umemiya-Shirafuji, Vivek K. Unni, María I. Vaccaro, Enza Maria Valente214,215, Greet Van den Berghe216, Ida J. van der Klei3,4, Wouter G. van Doorn, Linda F. van Dyk, Marjolein van Egmond, Leo A. van Grunsven217, Peter Vandenabeele218, Wim Vandenberghe, Ilse Vanhorebeek, Eva C. Vaquero3,4, Guillermo Velasco219, Tibor Vellai3,4, José Miguel Vicencio64, Richard D. Vierstra, Miquel Vila, Cécile Vindis, Giampietro Viola220, Maria Teresa Viscomi, Olga V. Voitsekhovskaja, Clarissa von Haefen, Marcela Votruba, Keiji Wada3,4, Richard Wade‐Martins, Cheryl L. Walker, Craig M. Walsh, Jochen Walter18, Xiang‐Bo Wan3,4, Aimin Wang3,4, Chenguang Wang204, Li Wang3,4, Fan Wang221, Guanghui Wang3,4, Haichao Wang3,4, Hong‐Gang Wang3,4, Horng‐Dar Wang3,4, Jin Wang3,4, Ke Wang222, Mei Wang223,224, Richard C. Wang3,4, Xinglong Wang167, Xiujie J. Wang3,4, Ying Wang3,4, Yipeng Wang3,4, Dieter Willbold3,4, Zhigang Charles Wang3,4, Zhinong Wang3,4, Derick G. Wansink, Diane McVey Ward, Hirotaka Watada, Sarah Waters, Paul Webster3,4, Lixin Wei3,4, Conrad C. Weihl, William A. Weiss3,4, Scott M. Welford, Long-Ping Wen3,4, Caroline A. Whitehouse, J. Lindsay Whitton, Alexander J. Whitworth, Tom Wileman54, John Wiley3,4, Simon Wilkinson3,4, Roger Williams, Peter R. Williamson, Bradly G. Wouters, Chenghan Wu3,4, Daocheng Wu3,4, William Ka Kei Wu3,4, Andreas Wyttenbach, Ramnik J. Xavier, Zhijun Xi3,4, Pu Xia3,4, Gengfu Xiao3,4, Zhiping Xie, Zhonglin Xie225, D Xu3,4, Jinxian Xu3,4, Liang Xu3,4, Xiaolei Xu3,4, Ai Yamamoto3,4, Akitsugu Yamamoto, Shunhei Yamashina, Michiaki Yamashita, Zhen Yan3,4, Mitsuhiro Yanagida, Dun‐Sheng Yang3,4, Elizabeth Yang3,4, Jin‐Ming Yang3,4, Shi Yu Yang3,4, Wannian Yang3,4, Wei Yang3,4, Zhihong Yang3,4, Meng-Chao Yao3,4, Tso-Pang Yao226, Behzad Yeganeh, Wei-Lien Yen, Jia-Jing Yin3,4, Xiao-Ming Yin3,4, Ook-Joon Yoo, Gyesoon Yoon, Seung-Yong Yoon, Tomohiro Yorimitsu, Yuko Yoshikawa, Tamotsu Yoshimori3,4, Kohki Yoshimoto, Ho Jin You3,4, Richard J. Youle, Anas Younes, Wen H. Yu3,4, Long Yu3,4, Seong-Woon Yu3,4, Zhi-Min Yuan, Zhenyu Yue3,4, Cheol‐Heui Yun, Michisuke Yuzaki3,4, Olga Zabirnyk3,4, David N. Zacks3,4, Eldad Zacksenhaus, Nadia Zaffaroni227, Zahra Zakeri, Herbert J. Zeh, Scott Zeitlin, Hong Zhang228,229, Shouxin Zhang, Jianhua Zhang230, Jingpu Zhang, Lin Zhang231, Long Zhang, Ming-Yong Zhang232, Xu Dong Zhang, Mantong Zhao, Yi‐Fang Zhao, Yongchao Zhao233, Zhizhuang Joe Zhao, Xiaoxiang Zheng3,4, Boris Zhivotovsky234, Qing Zhong, Cong‐Zhao Zhou235, Changlian Zhu236, Wei‐Guo Zhu3,4, Xiaofeng Zhu3,4, Xiongwei Zhu167, Yuangang Zhu3,4, Teresa Żołądek237, Wei‐Xing Zong, António Zorzano238, Jürgen Zschocke239, Brian S. Zuckerbraun
1Life Sciences Institute, and Departments of Molecular, Cellular and Developmental Biology and Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA
2Department of Biochemistry and Food Science; Hebrew University; Rehovot, Israel
3Biochemistry Department; Institute of Medical Biology; University of Tromsø; Tromsø, Norway
4University of Michigan; Life Sciences Institute; Rm. 6036; 210 Washtenaw Ave.; Ann Arbor, Michigan 48109-2216 USA
5Molecular and Cellular Biology (K.U. Leuven; Campus Gasthuisberg O/N-; Leuven - Belgium)
6Laboratoire Epigenetique et Cancer (7 rue Guy Moquet 94800 Villejuif France - France)
7Department of Pharmacology, Germany
8Immunobiologie des Cellules Dendritiques (25-28 rue du Docteur Roux, F-75724 Paris Cedex 15 - France)
9Cell Biology Program, Hospital for Sick Children, Toronto, Ontario, Canada
10Department of Biotechnology, University of Tokyo, Tokyo, Japan
11GéPITOS - Génétique, physiopathologie et ingénierie du tissu osseux (Avenue de Valombrose 06107 NICE CEDEX 2 - France)
12Department of Pathology & Laboratory Medicine; University of Cincinnati College of Medicine; Cincinnati, Ohio USA
13Department of Chemical and Biological Sciences, Japan Women’s University, Tokyo, Japan
14Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
15Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA
16FEMTO-ST - Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) (32 avenue de l'Observatoire 25044 BESANCON CEDEX - France)
17Safar Center for Resuscitation Research; Pittsburgh, Pennsylvania USA
18Buck Institute for Age Research, Novato, California, USA
19Department of Molecular and Human Genetics (Houston, Texas - United States)
20Jan and Dan Duncan Neurological Research Institute (Houston, Texas - United States)
21Medical Genetics (Department of Pediatrics, Naples - Italy)
22Telethon Institute for Genetics and Medicine (Via P. Castellino 111, 80131 Naples - Italy)
23Department of Biological Sciences, University of Toledo, Toledo, Ohio, USA
24Department of Genetics, Development and Cell Biology, and Plant Sciences Institute; Iowa State University; Ames, Iowa USA
25Signalisation et physiopathologie des cellules épithéliales (Faculté de pharmacie, Rue des Turlurets - Tour E1 92296 Chatenay-Malabry Cedex - France)
26Laboratoire de Génétique Moléculaire des Champignons; Institut de Biochimie et de Génétique Cellulaires; CNRS; Université de Bordeaux 2; Bordeaux, France
27DIMNP - Dynamique des interactions membranaires normales et pathologiques (BT 24 CC 107 Place Eugène Bataillon 34095 MONTPELLIER CEDEX 5 - France)
28IBGC - Institut de biochimie et génétique cellulaires (1 Rue Camille Saint-Saens 33077 BORDEAUX CEDEX - France)
29Basic Medical Sciences; Western University of Health Sciences; Pomona, California USA
30IRIM - Institut de Recherche en Infectiologie de Montpellier (UMR 9004, 1919 Route de Mende - 34293 Montpellier - France)
31Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA
32Celullar and Molecular Medicine (Spain)
33E2SNC / ESTROGENES - Estrogènes, Expression génique et pathologies du Système Nerveux Central - UFC (UFR ST 16 route de Gray 25030 Besançon Cedex - France)
34Infection bactérienne, inflammation, et carcinogenèse digestive (Faculté de médecine 28, avenue valombrose 6107 NICE CEDEX 2 - France)
35UNS - Université Nice Sophia Antipolis (1965 - 2019) (Parc Valrose, 06100 Nice - France)
36Division of Pharmacology, Faculty of Health Sciences, Linköping University, Linköping, Sweden
37Department of Medicine I; Division of Oncology; Institute of Cancer Research; Medical University of Vienna; Vienna, Austria
38Department of Computer Science [Tsukuba] (Room 3F900, Building F, Third area, University of Tsukuba, Tenoudai 1-1-1, Tsukuba science city, Ibaraki 305-8573, Japan - Japan)
39Gunma University (4-2 Aramaki-machi, Maebashi City, Gunma, 371-8510 Japan - Japan)
40Cell Biology, Physiology and Immunology (Spain)
41Department of Microbiology; Instituto de Fermentaciones Industriales; Madrid, Spain
42Dulbecco Telethon Institute/Department of Biology (Italy)
43Department of Biological Sciences; Korea Advanced Institute of Science and Technology; Republic of Korea
44National Creative Research Initiatives Center for Cell Growth Regulation;
45Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
46Department of Chemistry and HKU-CAS Joint Laboratory (Joint Laboratory on New Materials - China)
47Learning Sciences Lab (Singapore)
48Department of Immunology; Peking University; Center for Human Disease Genomics; Beijing, China
49COSS - Chemistry, Oncogenesis, Stress and Signaling (Université de Rennes1 - CLCC Eugène Marquis, Rue de la Bataille Flandres Dunkerque, Bat D, 35042 Rennes - France)
50Emory University School of Medicine, United States
51Division of Pulmonary and Critical Care Medicine; Brigham & Womens Hospital; Harvard Medical School; Boston, Massachusetts USA
52U753 - Cytokines et Immunologie des Tumeurs Humaines (Gustave Roussy. 114, rue Édouard-Vaillant 94805 Villejuif Cedex -France - France)
53Biology (Italy)
54Department of Chemistry and Biochemistry and the Molecular Biology Institute; University of California, Los Angeles; Los Angeles, California USA
55Strathclyde Institute of Pharmacy and Biomedical Sciences (United Kingdom)
56UIBC - Interactions Bactéries-Cellules (Département Biologie cellulaire et infection, 25-28 rue du Docteur Roux, F-75724 Paris Cedex 15 - France)
57Department of Experimental Medicine and Oncology (Italy)
58IGF - Institut de Génomique Fonctionnelle (141, Rue de la Cardonille 34094 Montpellier cedex 5 - France)
59CNV (Chile)
60Section of Haemato-oncology (sutton - United Kingdom)
61IMN - Institut des Maladies Neurodégénératives [Bordeaux] (Bât. 3b 1er étage 146 Rue Léo Saignat 33076 Bordeaux - France)
62Brunel University London [Uxbridge] (Kingston Lane, Uxbridge, Middlesex UB8 3PH - United Kingdom)
63The University of New Mexico [Albuquerque] (Albuquerque, Nouveau-Mexique 87131 - United States)
64Facultad de Ciencias Químicas y Farmacéuticas (Chile)
65Dpt. of Cancer & Cell Biology (The Vontz Center for Molecular Studies 3125 Eden Avenue Cincinnati, Ohio 45267 - United States)
66IJM (UMR_7592) - Institut Jacques Monod (Université Paris Diderot, Bât. Buffon, 15 rue Hélène Brion, 75205 Paris cédex 13 - France)
67Department of Cancer Biology; The Scripps Research Institute; Jupiter, Florida USA 35 INSERM U756, and the Université Paris-Sud 11; Châtenay-Malabry, France 36 Laboratorio de Biología Celular y Molecular-Instituto de Histología y Embriología; Universidad Nacional de Cuyo-CONICET; Mendoza, Argentina 37 Departamento de Morfología y Biología Celular; Universidad de Oviedo; Oviedo, Spain 38 Keck Graduate Institute of Applied Sciences; Claremont, California USA 39 Department of Anatomy and Structural Biology and of Developmental and Molecular Biology; Marion Bessin Liver Research Center; Albert Einstein College of Medicine; Bronx, New York USA 40 Department of Pathology; University of California, San Francisco; San Francisco, California USA 41 Laboratorio Nazionale Consorzio Interuniversitario Biotecnologie; Trieste, Italy 42 Department of Genome Science; University of Cincinnati; Cincinnati, Ohio USA 43 Medical Oncology Branch; National Cancer Institute/Navy Medical Oncology; Bethesda, Maryland USA 44 Department of Molecular Genetics and Microbiology; University of New Mexico Health Science Center; Albuquerque, New Mexico USA 45 Department of Biochemistry & Molecular Biology; and ARC Centre of Excellence in Structural and Functional Microbial Genomics; Monash University; Clayton Campus; Melbourne, Victoria, Australia 46 Department of Biology; University of Tor Vergata; via della Ricerca Scientifica; Rome, Italy 47 Department of Physiology; Tufts University; Boston, Massachusetts USA 48 Department of Neurology; Massachusetts General Hospital; Charlestown, Massachusetts USA 49 Department of Molecular, Cellular & Developmental Biology; Yale University; New Haven, Connecticut 50 Departments of Medicine, Pharmacology and Pathology; Comprehensive Cancer Center; Case Western Reserve University and University Hospitals of Cleveland; Cleveland, Ohio USA 51 Immunotec Research Ltd.; Quebec, Canada 52 Virologie et Immunologie Moleculaires; INRA UR892; Jouy-en-Josas, France 53 Department of Anatomy and Cell Biology; University of Florida College of Medicine; Gainesville, Florida USA 54 Department of Biochemistry; University of Tuebingen; Tuebingen, Germany 55 Baylor College of Medicine; Houston, Texas USA 56 Department of Biological Chemistry; The Weizmann Institute of Science; Rehovot, Israel 57 Department of Biological and Environmental Sciences; University of Helsinki; Helsinki, Finland 58 Departments of Biochemistry and Molecular Biology; Apoptosis and Genomics Researc
68Virologie humaine (46, Allee D'Italie 69364 LYON CEDEX 07 - France)
69IIB-INTECH - Instituto de Investigaciones Biotecnológicas [San Martín] (UNSAM - Campus Miguelete IIB - Instituto de Investigaciones Biotecnológicas, Av. 25 de Mayo y Francia CP(1650) San Martín, Prov. de Buenos Aires, Argentina - Argentina)
70HERPES - Virulence et Latence des Herpesvirus (I2BC, Bâtiment 21, 1 avenue de la Terrasse, 91198 Gif/Yvette cedex - France)
71I2BC - Institut de Biologie Intégrative de la Cellule (Bâtiment 21, 1 avenue de la Terrasse, 91198 Gif/Yvette cedex - France)
72MRC Centre for Developmental Neurobiology (United Kingdom)
73UniBs - Università degli Studi di Brescia = University of Brescia (Piazza del Mercato, 15 - 25121 Brescia - Italy)
74I2V - Immunité infection vaccination (CERVI 21, avenue tony garnier 69365 LYON CEDEX 07 - France)
75Dept of City and Regional Planning (Beijing - United Kingdom)
76Biochemistry and Molecular Biology (Hungary)
77Montreal Neurological Institute and Hospital (3801 University Street Montreal, QC H3A 2B4 - Canada)
78Dulbecco Telethon Institute-IRCCS Santa Lucia Foundation and Department of Biology; University of Rome Tor Vergata; Rome, Italy
79Department of Developmental Biology and Neurosciences (Japan)
80LBD - Laboratoire de Biologie du Développement [IBPS] (bat. C-30, 7° Etage, bte.24 9 Quai Saint-Bernard 75252 PARIS CEDEX 05 - France)
81LBD-E03 - C.elegans Hérédité et Développement = C.elegans heredity and development (France)
82Faculty of Medicine, Canada
83INRA - Institut National de la Recherche Agronomique (France)
84M2iSH - Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (UFR de Médecine et de Pharmacie, 28 Place Henri Dunant, BP 38, 63001 Clermont-Ferrand Cedex - France)
85IRCM - U896 Inserm - UM1 - Institut de recherche en cancérologie de Montpellier (208 rue des Apothicaires F-34298 Montpellier - France)
86ICT - Immunologie et chimie thérapeutiques (I.B.M.C. 15 Rue René Descartes 67084 STRASBOURG CEDEX - France)
87UNISTRA - Université de Strasbourg (4 rue Blaise Pascal - CS 90032 - 67081 Strasbourg cedex - France)
88C3M - Centre méditerranéen de médecine moléculaire (Hôpital de l'Archet, 151 rte Saint Antoine de Ginestiere 06204 Nice Cedex 3 - France)
89Département Digestif (151, route St Antoine de Ginestière 06200 Nice - France)
90Molecular Cell Biology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Haren, The Netherlands
91AIST - National Institute of Advanced Industrial Science and Technology (Higashi, Tsukuba, Ibaraki 305-8561 - Japan)
92Department of Oncology (France)
93School of Biochemistry and Immunology (Ireland)
94Department of Cellular and Structural Biology, University of Texas Health Science Center (San Antonio, TX 78229, U.S.A. - United States)
95Laboratoire de Pathologie Clinique et Expérimentale (Hôpital Louis Pasteur 30 avenue de la Voie Romaine 06000 Nice - France)
96Department of Biochemistry (Biotechnology Research Institute, Hong Kong, China - China)
97Danish Cancer Society (Department of Apoptosis, DK-2100 Copenhagen - Denmark)
98IBCP - Institut de biologie et chimie des protéines [Lyon] (7 Passage du Vercors 69367 LYON CEDEX 07 - France)
99Cancer Research UK London Research Institute (Lincoln's Inn Fields, London, WC2A 3LY - United Kingdom)
100Department of Molecular Microbiology and Immunology; University of Southern California Keck Medical School; Los Angeles, California USA
101Department of Applied Biological Chemistry, Niigata University, Niigata, Japan
102Cell Biology, section Radiation & Stress Cell Biology (United Kingdom)
103Department of Laboratory Medicine and Pathology; University of Minnesota Cancer Center; Minneapolis, Minnesota USA
104Department of Medicine & Pharmacology; Wayne State University School of Medicine; Detroit, Michigan USA
105Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
106Department of Molecular Genetics (76100 Rehovo - Israel)
107Department of Radiation Oncology; University Hospitals of Cleveland; Cleveland, Ohio USA
108Institute of Immunology (Campus Kiel Kiel - Germany)
109Institute for Immunology (Germany)
110Department of Cell Biology; Centro de Investigación Príncipe Felipe; Valencia, Spain
111Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
112Department of
113Department of Neuroscience (5323 Harry Hines Blvd, Dallas, Texas 75390-9111 - United States)
114CGPhiMC - Centre de génétique et de physiologie moléculaire et cellulaire (bat. 741 43 Bvd du 11 Novembre 1918 69622 VILLEURBANNE CEDEX - France)
115CRC (UMR_S 872) - Centre de Recherche des Cordeliers (CRBM des Cordeliers 15, rue de l'ecole de medecine batiment E 75270 Paris cedex 06 - France)
116Plateforme de métabolomique (Gustave Roussy - France)
117Pôle de biologie (75015 Paris - France)
118U848 - Apoptose, cancer et immunité (Gustave Roussy. 114, rue Édouard-Vaillant 94805 Villejuif Cedex -France - France)
119UPD5 Médecine - Université Paris Descartes - Faculté de Médecine (15 rue de l'École de médecine - 75270 Paris Cedex 06 - France)
120Department of Molecular Neuroscience (United Kingdom)
121Telethon Institute of Genetics and Medicine, Napoli, Italy
122CERN - European Organization for Nuclear Research (Route de Meyrin 385, 1217 Meyrin - Switzerland)
123CVIT - Center for Visual Information Technology [Hyderabad] (Gachibowli, Hyderabad - 500 032, Andhra Pradesh - India)
124Department of Biochemistry and Molecular Biology (The George Washigton, DC 20037 - United States)
125MIT - Massachusetts Institute of Technology (77 Massachusetts Ave, Cambridge, MA 02139 - United States)
126Centre for Cancer Biology (South Australia 5000 - Australia)
127Facultad de Medicina, Chile
128IGMM - Institut de Génétique Moléculaire de Montpellier (1919 Route de Mende - 34293 Montpellier Cedex 5 - France)
129Department of Pathology and Center for Neuroscience; University of Pittsburgh; Pittsburgh, Pennsylvania USA
130SeRAIC - Signalisation et Réponses aux Agents Infectieux et Chimiques (Faculté de Pharmacie, Rue du Professeur Léon Bernard, 35000 Rennes - France)
131OTOFAJ - Autophagie et Développement (I2BC, Bâtiment 21, 1 avenue de la Terrasse, 91198 Gif/Yvette cedex - France)
132NCKU - National Cheng Kung University (No.1, University Road, Tainan City 701, Taiwan - Taiwan)
133Microenvironnement et Physiopathologie de la Differenciation (Hopital Paul Brousse PARIS XI 12-16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX - France)
134HHMI - Howard Hughes Medical Institute [Chevy Chase] (4000 Jones Bridge Road, Chevy Chase, MD 20815-6789 - United States)
135University of Texas Southwestern Medical Center [Dallas] ( 5323 Harry Hines Boulevard Dallas, Texas, 75390 - United States)
136NUS - National University of Singapore (21 Lower Kent Ridge Rd, Singapour 119077 - Singapore)
137National Neuroscience Institute, Singapore
138Central China Normal University [Wuhan, China] (152 Luoyu Rd, Hongshan, Wuhan, Hubei, China - China)
139INRS-AFSB - Armand-Frappier Santé Biotechnologie Research Centre (531 boul. des Prairies Laval (Québec) H7V 1B7 - Canada)
140CIBMTR - Center for International Blood and Marrow Transplant Research (Atlanta, Georgia 30322 - United States)
141Center for Research on Biology and Pathology of Aging; University of Pisa; Pisa, Italy
142Departamento de Bioquímica y Biología Molecular (Facultad de Medicina, calle Fernando. Bongera s/n, 33006-Oviedo - Spain)
143Département de Biologie Cellulaire et de Morphologie, Université de Lausanne, Lausanne, Switzerland
144LIST (CEA) - Laboratoire d'Intégration des Systèmes et des Technologies (DRT/LIST Nano-INNOV Avenue de la Vauve 91120 Palaiseau - France)
145Equipe Labellisée Ligue Contre le Cancer, France
146JHU - Johns Hopkins University (Baltimore, Maryland 410-516-8000 - United States)
147IMB - Institute of Molecular Biosciences, Karl-Franzens University Graz, (Humboldtstraße 50/EG, 8010 Graz - Australia)
148Department of Pediatrics (Naples - Italy)
149Department of Experimental Pharmacology (Faculty of Biotechnological Sciences Napoli - Italy)
150Drug Research and Evaluation (Italy)
151Albert Einstein College of Medicine [New York] (300 Morris Park Avenue Bronx, NY 10461 - United States)
152Institute of Molecular Biology and Biotechnology (Heraklion - Greece)
153UMR ISEM - Institut des Sciences de l'Evolution de Montpellier (Place E. Bataillon CC 064 34095 Montpellier Cedex 05 - France)
154IBDC - Institut de signalisation, biologie du développement et cancer - Institute of Developmental Biology and Cancer (Centre Antoine lacassagne 33 Avenue de volombrose 06189 NICE CEDEX 2 - France)
155Departments of Neurology (United States)
156Departments of Pharmacology (United States)
157Vanderbilt University [Nashville] (Nashville, Tennessee, TN 37240 - United States)
158UMR5095 CNRS/Université de Bordeaux 2, Bordeaux, France
159Department of Cell Biology [New Haven] (333 Cedar Street PO Box 208002 New Haven, CT 06520-8002 - United States)
160Anatomic Pathology Section, Department of Human Pathology and Oncology (Siena - Italy)
161Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, USA
162HMS - Harvard Medical School [Boston] (25 Shattuck Street Boston, MA 02115 - United States)
163Depts of Radiation Oncology and Pathology (School of Medicine Detroit, Michigan - United States)
164USC Neuromuscular Center, Department of Neurology (Keck School of Medicine Good Samaritan Hospital Los Angeles, CA 90017 - United States)
165Department of Biology [Copenhagen] (Copenhagen Biocenter, Ole Maaløes Vej 5, DK-2200 Copenhagen N - Denmark)
166Department of Cell Biology and Biophysics (Greece)
167Department of Pathology (United States)
168UTSA - The University of Texas at San Antonio (1 UTSA Circle, San Antonio, TX 78249 - United States)
169Institute of Translational Medicine (United Kingdom)
170IBC - Institute of Biochemistry (Schafmattstr. 18 CH-8093 Zürich - Switzerland)
171Department of Biology (Rome - Italy)
172Hôpital Antoine Béclère (157 rue de la Porte de Trivaux, F-92141 Clamart Cedex - France)
173Innovation Thérapeutique : du Fondamental au Médicament (Faculté de Pharmacie 5, Rue J.B. Clément 92296 Chatenay-Malabry - France)
174Señalización Celular 4 (Spain)
175Department of Molecular Biology (Tuebingen - Germany)
176Center for Motor Neuron Biology and Disease Columbia University 650 West 168th Street (United States)
177Department of Neurology Columbia University 650 West 168th Street (United States)
178Department of Pathology and Cell Biology Columbia University 650 West 168th Street (United States)
179CC 101 (Place E. Bataillon 34095 Montpellier Cedex 05 - France)
180Department of Cell Biology and Morphology (Rue Bugnon 9 CH - 1005 Lausanne - Switzerland)
181UMCU - University Medical Center [Utrecht] (Heidelberglaan 100 3584 CX Utrecht - Netherlands)
182Service de dermatologie, France
183Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
184Vieillissement, stress, inflammation (France)
185CAM - University of Cambridge [UK] (The Old Schools, Trinity Lane, Cambridge CB2 1TN - United Kingdom)
186The Department of Chemical and Environmental Sciences (Limerick - Ireland)
187DMEM - Dynamique Musculaire et Métabolisme (INRA 2 place Viala 34060 Montpellier Cedex 1 - France)
188IRCCS Istituto Nazionale dei Tumori [Milano] (Via Giacomo Venezian, 1, 20133 Milano - Italy)
189Neurogenetics laboratory (Netherlands)
190Department of Pathology (Magdeburg - Germany)
191Experimental Tumor Pathology (Germany)
192Eye Hospital, Department of Ophthalmology, Jules-Gonin , (Lausanne, Switzerland 7These authors contributed equally to - Switzerland)
193Swiss Federal Institute of Technology (Lausanne, Switzerland - Switzerland)
194Unit of Oculogenomics (Sion - Switzerland)
195Division of regenerative Medicine (Milan - Italy)
196ICB - Instituto de Ciencias Biomédicas (Independencia 1027, Clasificador No. 7, Independencia, Santiago - Chile)
197Department of pathology (Boston, MA 02115 - United States)
198Department of Endocrine and Oncology Surgery (St. Leonards - Australia)
199Department of Surgery, Bankstown Hospital and South Western Sydney Clinical School (Sydney - Australia)
200MRC Human Immunology Unit (Weatherall Institute of Molecular Medicine University of Oxford Headley Way OX3 9DS Oxford, UK - United Kingdom)
201Department of Pharmacology and Molecular Sciences (3010 Bern - Switzerland)
202UNIGE - Université de Genève = University of Geneva (24 rue du Général-Dufour CH - 1211 Genève 4 Suisse - Switzerland)
203Muscular and Neurodegenerative Disease Unit (Genoa - Italy)
204Sidney Kimmel Cancer Center (Thomas Jefferson University campus, Philadelphia - United States)
205Department of Clinical and Experimental Medicine (Sweden)
206Cancer Institute (Huntley Street, London - United Kingdom)
207Department of Biochemistry and Biophysics (California 94143 - United States)
208Department of Experimental and Diagnostic Medicine and Interdisciplinary Center for Study of inflammation and ER-GenTech (via Borsari 44100 Ferrara - Italy)
209Laboratory of Molecular and Cellular Parasitology - Department of Microbiology (Singapore)
210CMPG - Center of Microbial and Plant Genetics (Heverlee-Leuven, Belgium - Belgium)
211Abramson Cancer Institute and Department of Cancer Biology (Philadelphia, PA 19104 - United States)
212IMPG - Instituto de Microbiologia Paulo de Góes [Rio de Janeiro] (Centro de Ciencias da saude CEP 21941-590 Rio de Janeiro-RJ - Brazil)
213Immunité Innée et Signalisation (25 rue du Docteur Roux, 75724 Paris cedex 15 - France)
214Department of Medical and Surgical Pediatrics (University Hospital, Messina - Italy)
215Istituto CSS Mendel [Rome, Italy] (Viale Regina Margherita, 261, 00198 Roma - Italy)
216Department of Intensive care Medicine (Leuven - Belgium)
217Department of Cell Biology (Belgium)
218Department for Molecular Biomedical Research (Belgium)
219Biochemistry and Molecular Biology (Spain)
220Department of Pediatrics, Italy
221Department of Chemistry (Beijing 100871 - China)
222Department of Mathematics (99 Shangda Road, BaoShan District, Shanghai - China)
223IRI - Institut de Recherche Interdisciplinaire [Villeneuve d'Ascq] (Parc de la Haute Borne 50 avenue de Halley BP 70478 59658 Villeneuve d'Ascq Cedex - France)
224Sch Mat Sci & Engn (Shandong Univ, Jinan 250100, Shandong - China)
225Division of Endocrinology and Diabetes (Department of Medicine,Oklahoma City, Oklahoma - United States)
226Department of Pharmacology and Cancer Biology (United States)
227Department of Experimental Oncology and Molecular Medicine (Italy)
228Institute of Modern Physics (Lanzhou 730000, China - China)
229Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province (Lanzhou 730000 - China)
230ICT - Institute of Computing Technology [Beijing] (6 Kexueyuan South Road Zhongguancun,Haidian District Beijing - China)
231ESRF - European Synchrotron Radiation Facility (6 rue Jules Horowitz BP220 38043 GRENOBLE CEDEX - France)
232Plant Physiology Laboratory (510650 Leyigu Guangzhou - China)
233Division of Biopharmaceutics (Leiden/Amsterdam Center for Drug Research, Gorlaeus Laboratories, Leiden University, The Netherlands - Netherlands)
234IMM - The Institute of Environmental Medicine [Stockholm] (SE-171 77 Stockholm, Sweden - Sweden)
235IBBMC - Institut de biochimie et biophysique moléculaire et cellulaire (bat. 430 91405 ORSAY CEDEX - France)
236Center for Brain Repair and Rehabilitation (Gothenburg - Sweden)
237department of genetics - Institute of biochemistry and biophysics (Pawinskiego 5a, 02-106 Warsaw - Poland)
238Departament de Bioquímica i Biologia Molecular (Barcelona - Spain)
239Chaperones Research Group (Germany)

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