Give or take? Intravenous immunoglobulin or plasma exchange for Guillain-Barré syndrome

Critical Care - Tập 15 - Trang 1-2 - 2011
Richard AC Hughes1
1Cochrane Neuromuscular Disease Group, MRC Centre for Neuromuscular Disease, London, UK

Tóm tắt

A new randomised controlled trial suggested that plasma exchange hastened removal from the ventilator in mechanically ventilated children with Guillain-Barré syndrome compared with intravenous immunoglobulin. Two larger trials in adults showed the opposite result.

Tài liệu tham khảo

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Raphaël JC, Chevret S, Hughes RAC, Annane D: Plasma exchange for Guillain-Barré syndrome (Cochrane review update). Cochrane Database Syst Rev. 2007, CD001798-

Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group: Randomised trial of plasma exchange, intravenous immunoglobulin, and combined treatments in Guillain-Barré syndrome. Lancet. 1997, 349: 225-230.

van der Meché FGA, Schmitz PIM, Dutch Guillain-Barré Study Group: A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barré syndrome. New Engl J Med. 1992, 326: 1123-1129. 10.1056/NEJM199204233261705.