Genotypes Associated With Reduced Activity of VKORC1 and CYP2C9 and Their Modification of Acenocoumarol Anticoagulation During the Initial Treatment Period

Clinical Pharmacology and Therapeutics - Tập 85 Số 4 - Trang 379-386 - 2009
Martina Teichert1,2, Rhn van Schaik3,4, Albert Hofman1, André G. Uitterlinden3,1,5, PAGM de Smet6,2, B. H. Ch. Stricker5,7, L E Visser1,8
1Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
2Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
3Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, The Netherlands
4Star‐Medical Diagnostic Center, Rotterdam, the Netherlands
5Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
6Centre for Quality of Care Research, UMC St Radboud, Nijmegen, The Netherlands
7Drug Safety Unit, Inspectorate for Health Care, The Hague, The Netherlands
8Department of Hospital Pharmacy, Erasmus Medical Center, Rotterdam, The Netherlands

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