Genotoxicity of pesticides: a review of human biomonitoring studies
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US EPA Pesticide Industry Sales and Usage: 1996 and 1997 Market Estimates, http://www.epa.gov/oppbead1/pestsales/97pestsales.
Eddleston, 2002, Pesticide poisoning in the developing world, a minimum pesticides list, Lancet, 360, 1163, 10.1016/S0140-6736(02)11204-9
IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, vol. 1, 1971 to vol. 82, 2002.
Zahm, 1997, Pesticides and cancer, Occup. Med. State Art Rev., 12, 269
Zahm, 1998, Pesticides and childhood cancer, Environ. Health Perpect., 106, 893
Daniels, 1997, Pesticides and childhood cancers, Environ. Health Perspect., 105, 1068, 10.1289/ehp.971051068
Khuder, 1997, Meta-analyses of multiple myeloma and farming, Am. J. Ind. Med., 32, 510, 10.1002/(SICI)1097-0274(199711)32:5<510::AID-AJIM11>3.0.CO;2-5
Restrepo, 1990, Birth defects among children born to a population occupationally exposed to pesticides in Colombia, Scand. J. Work Environ. Health, 16, 239, 10.5271/sjweh.1789
Rojas, 2000, Congenital malformations and pesticide exposure, Rev. Med. Chil., 128, 399, 10.4067/S0034-98872000000400006
Schwartz, 1988, Congenital limb reduction defects in the agricultural setting, Am. J. Public Health, 78, 654, 10.2105/AJPH.78.6.654
Abell, 2000, Time to pregnancy among female greenhouse workers, Scand. J. Work Environ. Health, 26, 131, 10.5271/sjweh.522
C. Bolognesi, F. Merlo, Biomonitoring of human populations exposed to pesticides, in: P.E. Chereminisoff (Ed.), Encyclopedia of Environmental Control Technology, Gulf Publishing Company, Houston, 1995, Chapter 28, pp. 673–737.
IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, Genetic and Related Effects: An Updating of Selected IARC Monographs, vols. 1–42, Suppl. 6, 1987.
Dearfield, 1999, A survey of EPA/OPP and open literature on selected pesticide chemicals. II. Mutagenicity and carcinogenicity of selected chloroacetanilides and related compounds, Mutat. Res., 443, 183, 10.1016/S1383-5742(99)00019-8
Dearfield, 1993, A survey of EPA/OPP and open literature data on selected pesticide chemicals tested for mutagenicity. I. Introduction and first ten chemicals, Mutat. Res., 297, 197, 10.1016/0165-1110(93)90018-I
Garrett, 1986, Evaluation of the genetic activity profiles of 65 pesticides, Mutat. Res., 168, 301, 10.1016/0165-1110(86)90024-2
Popescu, 1999, Sister chromatid exchange formation in mammalian cells is modulated by deoxyribonucleotide pool imbalance, Somatic Cell Mol. Genet., 25, 101, 10.1023/B:SCAM.0000007145.65508.d0
Ashman, 1981, Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance, Mol. Cell. Biol., 1, 254, 10.1128/MCB.1.3.254
Hagmar, 1994, Cancer risk in human predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic Study Group on the Health Risk of Chromosome Damage, Cancer Res., 54, 2919
Hagmar, 1998, The European Study Group on Cytogenetic Biomarkers and Health, Chromosomal aberrations in lymphocytes predict human cancer. A report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH), Cancer Res., 58, 4117
Fucic, 2000, Estimation of genome damage after exposure to ionising radiation and ultrasound used in industry, Environ. Mol. Mutagen., 36, 47, 10.1002/1098-2280(2000)36:1<47::AID-EM7>3.0.CO;2-A
Vaglenov, 1999, Genotoxicity and radioresistance in electroplating workers exposed to chromium, Mutat. Res., 446, 23, 10.1016/S1383-5718(99)00145-X
Somorovska, 1999, Biomonitoring of genotoxic risk in workers in a rubber factory, comparison of the Comet assay with cytogenetic methods and immunology, Mutat. Res., 445, 181, 10.1016/S1383-5718(99)00125-4
Fenech, 1997, A more comprehensive application of the micronucleus technique for biomonitoring of genetic damage rates in human populations. Experiences from the Chernobyl catastrophe, Environ. Mol. Mutagen., 30, 112, 10.1002/(SICI)1098-2280(1997)30:2<112::AID-EM3>3.0.CO;2-P
Sinues, 1991, Sister chromatid exchanges, proliferating rate index, and micronuclei biomonitoring of internal exposure to vinyl chloride monomer in plastic industry workers, Toxicol. Appl. Pharmacol., 108, 37, 10.1016/0041-008X(91)90266-H
Joksic, 1997, Cytogenetic monitoring of pesticide sprayers, Environ. Res., 75, 113, 10.1006/enrs.1997.3753
Falck, 1999, Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1,GSTT1 and NAT2 in pesticide-exposed greenhouse workers, Mutat. Res., 441, 225, 10.1016/S1383-5718(99)00051-0
Bolognesi, 1993, Cytogenetic analysis of a human population occupationally exposed to pesticides, Mutat. Res., 285, 239, 10.1016/0027-5107(93)90112-S
Bolognesi, 2002, Micronucleus monitoring of a floriculturist population from western Liguria, Italy, Mutagenesis, 17, 391, 10.1093/mutage/17.5.391
Garaj-Vrhovac, 1999, Chromosomal aberrations and frequency of micronuclei in workers employed in pesticide production, Biologia, 54, 707
Garaj-Vrhovac, 2001, Cytogenetic monitoring of Croatian population occupationally exposed to a complex mixture of pesticides, Toxicology, 165, 153, 10.1016/S0300-483X(01)00419-X
Anonymous, Epidemiological surveillance system for acute pesticide poisoning, Epidemiol. Bull. 22 (2001) 6–11.
Viertel, 2001, Cases of acute poisoning admitted to a medical intesive care unit, Dtsch. Med. Wochenschr., 126, 1159, 10.1055/s-2001-17890
Van Bao, 1974, Chromosome aberrations in patients suffering acute organic phosphate insecticide intoxication, Humangenetik, 24, 33
Czeizel, 1994, Phenotypic and cytogenetic studies in self-poisoned patients, Mutat. Res., 313, 175, 10.1016/0165-1161(94)90047-7
Larripa, 1983, Sister chromatid exchanges in a human population accidentally exposed to an organophosphorus pesticide, Rev. Brasil. Genet. VI, 4, 719
Jablonika, 1989, Analysis of chromosome aberrations and sister-chromatid exchanges in peripheral blood lymphocytes of workers with occupational exposure to the mancozeb containing fungicide Novozir Mn80, Mutat. Res., 224, 143, 10.1016/0165-1218(89)90148-1
Kaioumova, 1998, Cytogenetic characteristics of herbicide production workers in Ufa, Chemosphere, 37, 1755, 10.1016/S0045-6535(98)00240-9
Padmavathi, 2000, Frequencies of SCEs in peripheral blood lymphocytes of pesticide workers, Bull. Environ. Contam. Toxicol., 64, 155, 10.1007/s001289910024
Laurent, 1996, Unexpected decrease in cytogenetic biomarkers frequencies observed after increased exposure to organo-phosphorous pesticides in a production plant, Int. Arch. Occup. Environ. Health, 68, 399, 10.1007/BF00377859
De Cassia Stocco, 1982, Cytogenetic study of workers exposed to methyl-parathion, Mutat. Res., 103, 71, 10.1016/0165-7992(82)90089-6
Maroni, 2000, Biological monitoring of pesticide exposure: a review, Toxicology, 143, 1
Zeljezic, 2001, Chromosomal aberration and single cell gel electrophoresis (Comet) assay in the longitudinal risk assessment of occupational exposure to pesticides, Mutagenesis, 16, 359, 10.1093/mutage/16.4.359
Zeljezic, 2002, Sister chromatid exchange and proliferative rate index in the longitudinal risk assessment of occupational exposure to pesticides, Chemosphere, 46, 295, 10.1016/S0045-6535(01)00073-X
Garaj-Vrhovac, 2002, Assessment of genome damage in a population of Croatian workers employed in pesticide production by Chromosomal aberration analysis micronucleus assay and comet assay, J. Appl. Toxicol., 22, 249, 10.1002/jat.855
Douglas, 1985, Alkaline sucrose sedimentations, sister-chromatid exchange and micronucleus assay in CHO cells, Progr. Mutat. Res., 5, 359
Natarajan, 1985, Tests for chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary (CHO) cells in culture, Progr. Mutat. Res., 5, 433
Mohtashamipur, 1985, Effects of ethylbenzene, toluene and xylene on the induction of micronuclei in bone marrow polychromatic erythrocytes of mice, Arch. Toxicol., 58, 106, 10.1007/BF00348318
Mohtashamipur, 1987, Effects of pre-treatment of male NMRI mice with enzyme inducers or inhibitors on clastogenicity of toluene, Arch. Toxicol., 60, 460, 10.1007/BF00302390
Eastmond, 2000, Benzene-induced genotoxicity: a different perspective, J. Toxicol. Environ. Health, 61, 353, 10.1080/00984100050166352
Whysner, 2000, Benzene-induced genotoxicity, J. Toxicol. Environ. Health, 61, 347, 10.1080/00984100050166343
Garry, 1989, Human genotoxicity: pesticide applicators and phosphine, Science, 246, 251, 10.1126/science.2799386
Garry, 1992, Chromosome rearrangements in fumigant appliers: possible relationship to non-Hodgkin’s lymphoma risk, Cancer Epidemiol. Biomarkers Prev., 1, 287
Barbosa, 1994, Evaluation of phosphine genotoxicity at occupational levels of exposure in New South Wales, Australia, Occup. Environ. Med., 51, 700, 10.1136/oem.51.10.700
Barbosa, 1994, Determination of genotoxic and other effects in mice following short term repeated dose and subchronic inhalation exposure to phosphine, Environ. Mol. Mutagen., 24, 81, 10.1002/em.2850240202
Linnainmaa, 1983, Sister chromatid exchanges among workers occupationally exposed to phenoxy acid herbicides 2,4-D and MCPA, Teratogen. Carcinogen. Mutagen., 3, 269, 10.1002/1520-6866(1990)3:3<269::AID-TCM1770030306>3.0.CO;2-F
Mustonen, 1986, Effects of phenoxyacetic acids on the induction of chromosome aberrations in vitro and in vivo, Mutagenesis, 1, 241, 10.1093/mutage/1.4.241
Hogstedt, 1980, Cytogenetic study of pesticides in agricultural work (brief reports), Hereditas, 92, 177, 10.1111/j.1601-5223.1980.tb01692.x
Figgs, 2000, Increased lymphocyte replicative index following 2,4-dichlorophenoxyacetic acid herbicide exposure, Cancer Causes Control, 11, 373, 10.1023/A:1008925824242
Calvert, 1998, Genotoxicity in workers exposed to methyl bromide, Mutat. Res., 417, 115, 10.1016/S1383-5718(98)00105-3
Steenland, 1997, Thyroid hormones and cytogenetic outcomes in backpack sprayers using ethylenebis (dithiocarbamate) (EBDC) fungicides in Mexico, Environ. Health Perspect., 105, 1126, 10.1289/ehp.971051126
Titenko-Holland, 1997, Genotoxicity of malathion in human lymphocytes assessed using the micronucleus assay in vitro and in vivo: a study of malathion-exposed workers, Mutat. Res., 388, 85, 10.1016/S1383-5718(96)00140-4
Steenland, 1986, A cytogenetic study of papaya workers exposed to ethylene dibromide, Mutat. Res., 170, 151, 10.1016/0165-1218(86)90029-7
Rupa, 1989, Analysis of sister-chromatid exchanges, cell kinetics and mitotic index in lymphocytes of smoking pesticide sprayers, Mutat. Res., 223, 253, 10.1016/0165-1218(89)90053-0
Rupa, 1988, Screening of chromosomal aberrations and sister chromatid exchanges in peripheral lymphocytes of vegetable garden workers, Hum. Toxicol., 7, 333, 10.1177/096032718800700406
Kourakis, 1992, Frequencies of chromosomal aberrations in pesticide sprayers working in plastic green houses, Mutat. Res., 279, 145, 10.1016/0165-1218(92)90256-Y
Rupa, 1991, Frequency of sister chromatid exchange in peripheral lymphocytes of male pesticide applicators, Environ. Mol. Mutagen., 18, 136, 10.1002/em.2850180209
Lander, 1995, Frequency of sister chromatid exchange and hematological effects in pesticide-exposed greenhouse sprayers, Scand. J. Work Environ. Health, 21, 283, 10.5271/sjweh.39
Nehez, 1981, Data on the chromosome examinations of workers exposed to pesticides, Regul. Toxicol. Pharmacol., 1, 116, 10.1016/0273-2300(81)90089-1
Rita, 1987, Monitoring of workers occupationally exposed to pesticides in grape gardens of Andhra Pradesh, Environ. Res., 44, 1, 10.1016/S0013-9351(87)80081-6
Paldy, 1987, Cytogenetic studies on rural populations exposed to pesticides, Mutat. Res., 187, 127, 10.1016/0165-1218(87)90079-6
M. Nehez, P. Boros, A. Ferke, J. Mohos, M. Palotas, G. Vetro, M. Zimanyl, I. Desi, Cytogenetic examination of people working with agrochemicals in the southern region of Hungary, Regul. Toxicol. 8 (1988) 37–44.
Rupa, 1989, Chromosomal aberrations in peripheral lymphocytes of cotton field workers exposed to pesticides, Environ. Res., 49, 1, 10.1016/S0013-9351(89)80017-9
Rupa, 1989, Frequencies of chromosomal aberrations in smokers exposed to pesticides in cotton fields, Mutat. Res., 22, 37, 10.1016/0165-1218(89)90033-5
Rupa, 1991, Clastogenic effect of pesticides in peripheral lymphocytes of cotton-field workers, Mutat. Res., 261, 177, 10.1016/0165-1218(91)90065-T
Mohammad, 1995, Chromosomal aberrations in human lymphocytes from two groups of workers occupationally exposed to pesticides in Syria, Environ. Res., 70, 24, 10.1006/enrs.1995.1042
Amr, 1999, Pesticide monitoring and its health problems in Egypt, a Third World country, Toxicol. Lett., 107, 1, 10.1016/S0378-4274(99)00026-0
Pasquini, 1996, Cytogenetic biomonitoring of pesticide exposed farmers in central Italy, J. Environ. Pathol. Toxicol. Oncol., 15, 29
Venegas, 1998, Micronuclei analysis in lymphocytes of pesticide sprayers from Concepcion, Chile, Teratogen. Carcinogen. Mutagen., 18, 123, 10.1002/(SICI)1520-6866(1998)18:3<123::AID-TCM3>3.0.CO;2-I
Kourakis, 1996, Cytogenetic effects of occupational exposure in the peripheral blood lymphocytes of pesticide sprayers, Carcinogenesis, 17, 99, 10.1093/carcin/17.1.99
Dulout, 1985, Sister-chromatid exchanges and chromosomal aberrations in a population exposed to pesticides, Mutat. Res., 143, 237, 10.1016/0165-7992(85)90087-9
De Ferrari, 1991, Cytogenetic biomonitoring of an Italian population exposed to pesticides: chromosome aberration and sister chromatid exchange analysis in peripheral blood lymphocytes, Mutat. Res., 260, 105, 10.1016/0165-1218(91)90086-2
Carbonell, 1993, Cytogenetic biomonitoring in a Spanish group of agricultural workers exposed to pesticides, Mutagenesis, 8, 511, 10.1093/mutage/8.6.511
Carbonell, 1995, Temporary variations in chromosomal aberrations in a group of agricultural workers exposed to pesticides, Mutat. Res., 344, 127, 10.1016/0165-1218(95)00051-8
Lander, 2000, Chromosome aberrations in pesticide-exposed greenhouse workers, Scand. J. Work. Environ. Health, 26, 436, 10.5271/sjweh.565
Dulout, 1992, Analysis of sister chromatid exchanges (SCE) in human population studies, Rev. Brasil. Genet., 15, 169
Shaham, 2001, Frequency of sister-chromatid exchange among greenhouse farmers exposed to pesticides, Mutat. Res., 491, 71, 10.1016/S1383-5718(01)00130-9
Gomez-Arroyo, 2000, Cytogenetic biomonitoring in a Mexican floriculture worker group exposed to pesticides, Mutat. Res., 466, 117, 10.1016/S1383-5718(99)00231-4
Bolognesi, 1993, Frequency of micronuclei in lymphocytes from a group of floriculturists exposed to pesticides, J. Toxicol. Environ. Health, 40, 405, 10.1080/15287399309531807
Scarpato, 1996, Cytogentic monitoring of a group of Italian floriculturists. No evidence of DNA damage related to pesticide exposure, Mutat. Res., 367, 73, 10.1016/0165-1218(95)00071-2
Carbonell, 1990, Sister chromatid exchange in lymphocytes of agricultural workers exposed to pesticides, Mutagenesis, 5, 403, 10.1093/mutage/5.4.403
Dulout, 1987, Cytogenetic analysis in plant breeders, Mutat. Res., 189, 381, 10.1016/0165-1218(87)90046-2
Au, 1999, Cytogenetic effects from exposure to mixed pesticides and the influence from genetic susceptibility, Environ. Health Perspect., 107, 501, 10.1289/ehp.99107501
Antonucci, 2000, Chromosomal aberrations analysis in a Brazilian population exposed to pesticides, Teratogen. Carcinogen. Mutagen., 20, 265, 10.1002/1520-6866(2000)20:5<265::AID-TCM2>3.0.CO;2-#
Gomez-Arroyo, 1992, Sister-chromatid exchange analysis in a rural population of Mexico exposed to pesticides, Mutat. Res., 281, 173, 10.1016/0165-7992(92)90005-3
Bolognesi, 1995, Genotoxic risk from occupational exposure to pesticides in floriculture, Clin. Chem., 41, 1919, 10.1093/clinchem/41.12.1919
Davies, 1998, Cytogenetic analysis of South Asian berry pickers in British Columbia using the micronucleus assay in peripheral lymphocytes, Mutat. Res., 416, 101, 10.1016/S1383-5718(98)00071-0
Hoyos, 1996, Cytogenetic monitoring of farmers exposed to pesticides in Colombia, Environ. Health Perspect., 104, 535
D’Arce, 2000, Cytogenetic and molecular biomonitoring of agricultural workers exposed to pesticide in Brazil, Teratogen. Carcinogen. Mutagen., 20, 161, 10.1002/(SICI)1520-6866(2000)20:3<161::AID-TCM7>3.0.CO;2-5
Lucero, 2000, Cytogenetic biomonitoring of Spanish greenhouse workers exposed to pesticides: micronuclei analysis in peripheral blood lymphocytes and buccal epithelial cells, Mutat. Res., 464, 255, 10.1016/S1383-5718(99)00200-4
Pastor, 2001, Micronuclei in peripheral blood lymphocytes and buccal epithelial cells of Polish farmers exposed to pesticides, Mutat. Res., 495, 147, 10.1016/S1383-5718(01)00206-6
Pastor, 2001, Cytogenetic analysis of Greek farmers using the micronucleus assay in peripheral lymphocytes and buccal cells, Mutagenesis, 16, 539, 10.1093/mutage/16.6.539
Pastor, 2002, A follow up study on micronucleus frequency in Spanish agricultural workers exposed to pesticides, Mutagenesis, 17, 79, 10.1093/mutage/17.1.79
Pastor, 2002, Occupational exposure to pesticides and cytogenetic damage: results of a Hungarian population study using the micronucleus assay in lymphocytes and buccal cells, Environ. Mol. Mutagen., 40, 101, 10.1002/em.10100
Musio, 1996, Common and rare fragile sites on human chromosomes, Cancer Genet. Cytogenet., 88, 184, 10.1016/0165-4608(95)00287-1
Yunis, 1987, Fragile sites are targets in diverse mutagens and carcinogens, Oncogene, 1, 59
Sbrana, 1995, Enhanced expression of common fragile sites with occupational exposure to pesticides, Cancer Genet. Cytogenet., 82, 123, 10.1016/0165-4608(95)00020-P
Musio, 1997, Aphidicolin-sensitive specific common fragile sites: a biomarker of exposure to pesticides, Environ. Mol. Mutagen., 29, 250, 10.1002/(SICI)1098-2280(1997)29:3<250::AID-EM4>3.0.CO;2-G
Webster, 2002, Organophosphate-based pesticides and genetic damage implicated in bladder cancer, Cancer Genet. Cytogenet., 133, 112, 10.1016/S0165-4608(01)00576-3
L.G. Sulbatos, Role of glutathione in the mammalian detoxification of organophosphorous insecticides, in: Organophosphorous Chemistry, Fate and Effects, Academic Press, New York, 1992, pp. 155–158.
Sulbatos, 1994, Mammalian toxicology of organophosphorous pesticides, J. Toxicol. Environ. Health, 43, 271, 10.1080/15287399409531921
Koop, 1992, Oxidative and reductive metabolism by cytochrome P450 2E1, FASEB J., 6, 724, 10.1096/fasebj.6.2.1537462
Kim, 1990, Role of 450 IIE1 in the metabolism 3-hydroxypyridine, a constituent of tobacco smoke redox cycling and DNA strand scission by the metabolite 2,5-dihydroxypiridine, Cancer Res., 50, 5333
Bartsch, 1984, Relevance of nitrosamines to human cancer, Carcinogenesis, 5, 1381, 10.1093/carcin/5.11.1381
Guengerichi, 1991, Role of human cytochrome P450 IIE1 in the oxidation of many low molecular weight cancer suspects, Chem. Res. Toxicol., 4, 168, 10.1021/tx00020a008
Girre, 1994, Assessment of cytochrome P450 2E1 induction in alcoholic patients by chloroxazone pharmacokinetics, Biochem. Pharmacol., 47, 1503, 10.1016/0006-2952(94)90524-X
Yardley-Jones, 1991, The toxicity of benzene and its metabolism and molecular pathology in human risk assessment, Br. J. Ind. Med., 48, 437
Elkstrom, 1989, Human liver microsomal cytochorme P-450 IIE1: immunological evaluation of contribution to microsome ethanol oxidation carbon tetrachloride reduction and NADPH oxidase activity, Biochem. Pharmacol., 38, 689, 10.1016/0006-2952(89)90217-7
Wrighton, 1986, Characterization of ethanol inducible human liver N-nitrosodimethylamine demethylase, Biochemistry, 25, 6732, 10.1021/bi00370a001
Kim, 1996, In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians, J. Pharmacol. Exp. Ther., 279, 4
Hirvonen, 1993, The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphism in a Finnish study population, Carcinogenesis, 14, 85, 10.1093/carcin/14.1.85
Uematsu, 1991, Association between restriction fragment length polymorphism of the human cytochrome P450 2E1 gene and susceptibility to lung cancer, Jpn. J. Cancer Res., 82, 254, 10.1111/j.1349-7006.1991.tb01838.x
E. Hodgson, I.S. Silver, L.E. Butler, M.P. Lawton, P.E. Levi, Metabolism, in: W.J. Hayes, E.R. Laws (Eds.), Handbook of Pesticides Toxicology, vol. 1, Academic Press, San Diego, 1991, pp. 106–167.
A. d’Errico, N. Malats, P. Vineis, P. Boffetta, Review of studies of selected metabolic polymorphism and cancer, in: P. Vineis, N. Malats, M. Lang, A. d’Errico, N. Caporaso, J. Cuzick, P. Boffetta (Eds.), Metabolic Polymorphism and Susceptibility to Cancer, vol. 148, IARC Scientific Publications, IARC, Lyon, France, 1999, pp. 223–293.
Coles, 1990, The role of glutathione and glutathione transferases in chemical carcinogenesis, Crit. Rev. Biochem. Mol. Biol., 25, 47, 10.3109/10409239009090605
Eaton, 2000, Biotrasformation enzyme polymorphism and pesticide susceptibility, Neurotoxicology, 21, 101
Grant, 1993, Molecular genetics of the N-acetyltransferases, Pharmacogenetics, 3, 45, 10.1097/00008571-199302000-00005
Kadlubar, 1992, Polymorphism of aromatic amine metabolism in human relevance for human carcinogenesis, Environ. Health Perspect., 98, 69, 10.1289/ehp.929869
Smitz, 1997, Two specific and simple methods for genotyping of the paraoxonase/arylesterase A/B polymorphism, Genet. Anal., 1, 11
Humbert, 1993, The molecular basis of the human serum paraoxonase activity polymorphism, Nat. Genet., 3, 73, 10.1038/ng0193-73
Furlog, 2000, The PON1 gene and detoxication, Neurotoxicology, 21, 581
Costa, 1999, The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism, Chem. Biol. Interact., 119, 429, 10.1016/S0009-2797(99)00055-1
Clapper, 2000, Genetic polymorphism and cancer risk, Curr. Oncol. Rep., 2, 251, 10.1007/s11912-000-0075-z
Pavanello, 2000, Biological indicators of genotoxic risk and metabolic polymorphisms, Mutat. Res., 463, 285, 10.1016/S1383-5742(00)00051-X
Scarpato, 1996, Cytogenetic monitoring of occupational exposure to pesticides: characterization of GSTM1, GSTT1, and NAT2 genotypes, Environ. Mol. Mutagen., 27, 263, 10.1002/(SICI)1098-2280(1996)27:4<263::AID-EM3>3.0.CO;2-E
Scarpato, 1997, Influence of GSTM1 and GSTT1 polymorphisms on the frequency of chromosome aberrations in lymphocytes of smokers and pesticide-exposed greenhouse workers, Mutat. Res., 389, 227, 10.1016/S1383-5718(96)00152-0
Makness, 1997, Effect of the molecular polymorphisms of human paraoxonase (PON1) on the rate of hydrolysis of paraoxon, Br. J. Pharmacol., 122, 265, 10.1038/sj.bjp.0701390
Padungtod, 1999, Paraoxonase polymorphism and its effect on male reproductive outcomes among Chinese pesticide factory workers, Am. J. Ind. Med., 36, 379, 10.1002/(SICI)1097-0274(199909)36:3<379::AID-AJIM5>3.0.CO;2-8
La Du, 2001, Serum paraoxonase (PON1) isozymes: the quantitative analysis of isozymes affecting individual sensitivity to environmental chemicals, Drug Metabol. Disposit., 29, 566
Cherry, 2002, Paraoxonase (PON1) polymorphisms in farmers attributing ill health to sheep dip, Lancet, 359, 763, 10.1016/S0140-6736(02)07847-9
Freitas, 2000, Population biology of lymphocytes: the flight for survival, Ann. Rev. Immunol., 18, 83, 10.1146/annurev.immunol.18.1.83
Freitas, 1986, Lifespan of B lymphocytes: the experimental basis for conflicting results, J. Immunol., 136, 470, 10.4049/jimmunol.136.2.470
Weisenburger, 1990, B-cell neoplasia: a conceptual understanding based on the normal humoral immune response, Pathol. Annu., 25, 99