Gương mặt hiện tại của cấy ghép tim

Springer Science and Business Media LLC - Tập 26 - Trang 4-13 - 1994
S. Schüler1, M. Loebe1, R. Hetzer1
1Abteilung für Herz-, Thorax- und Gefäßchirurgie, Deutsches Herzzentrum Berlin, Berlin

Tóm tắt

Cấy ghép tim hiện nay là phương pháp điều trị lựa chọn cho bệnh nhân mắc bệnh tim giai đoạn cuối với tỷ lệ sống sót trung và dài hạn tốt có thể dự đoán. Những kết quả khả quan đã dẫn đến một số phát triển mới trong những năm gần đây: mở rộng sự lựa chọn người nhận, cải thiện liệu pháp ức chế miễn dịch, giới thiệu chẩn đoán thải loại không xâm lấn, sử dụng hệ thống hỗ trợ tuần hoàn cơ học để cầu nối cho bệnh nhân bị suy tim rõ rệt cho đến khi cấy ghép, mở rộng tiêu chí lựa chọn cho trái tim hiến tặng và nâng cao hiểu biết về các vấn đề lâu dài của trái tim đã được cấy ghép. Một quy trình điều trị hậu phẫu chuẩn hóa và an toàn hiện cho phép một mức độ phục hồi cao và tỷ lệ mắc bệnh thấp cho bệnh nhân sau cấy ghép tim.

Từ khóa

#cấy ghép tim #bệnh tim giai đoạn cuối #tỷ lệ sống sót #ức chế miễn dịch #chẩn đoán thải loại #hỗ trợ tuần hoàn cơ học

Tài liệu tham khảo

Albert W, Warnecke H, Hummel M, Müller J, Schüler S, Hetzer R: Psychiatrisch-psychosomatische Syndrome bei herztransplantierten Patienten. Z Kardiol 1991;80(Suppl 3): 103. Bailey LL, Fricker FJ, Seltman KD: Proceedings of the Loma Linda International Conference on Pediatric Heart Transplantation. J Heart Lung Transplant 1991;10:787. Barnard CN: The operation, a human cardiac transplant: an interim report of a successful operation at Groote Schuur Hospital. Cape Town. S Afr Med J 1967;41:1271. Barnard CN, Wolpowitz A: Heterotopic versus orthotopic heart transplantation. Transplant Proc 1979;11:309. Belzer FO, Southard JH: Principles of solid-organ preservation by cold storage. Transplantation 1988;45:673. Billingham ME: Some recent advances in cardiac pathology. Hum Pathol 1979;10:367. Billingham ME, Path FRC: Dilemma of variety of histopathologic grading systems for acute cardiac allograft rejection by endomyocardial biopsy. J Heart Transplant 1990;9:272. Cabrol C, Gandjbakhch, Pavie A, Bors V, Rabago G, Muneretto C, Solis E, Cabrol A, Leger PH, Levasseur JP, Vaissier E, Petrie J, Desruennes M, Szefner J, Auriol A, Aupetit B: Heart Transplantation: Update. In Terasaki P (ed): Clinical Transplants 1989. Los Angeles, UCLA, 1989, p 79. Cabrol C, Gandjbakhch I, Pavie A, Bors V, Mestiti T, Cabrol A, Leger P, Levasseur JP, Vassier E, Szepner J, Auriol A, Amperi B, Solis E: Total artificial hearts as a bridge for transplantation: La Pitie 1986 to 1987. J Heart Transplant 1988;7:12. Carrel A, Guthrie CC: The transplantation of veins and organs. Am J Med 1905;11:1101. Casale AS, Bulkley GB, Bulkley BH, Flakerty JT, Lott VL, Lardner TJ: Oxygen free-radical scavengers protect the arrested, globally ischemic heart upon reperfusion. Surg Forum 1986;34:313. Caves PK, Stinson EB, Billingham ME, Shumway NE: Percutaneous transvenous endomyocardial biopsy in human heart recipients (experience with a bew technique). Ann Thorac Surg 1973;16:325. Choong YS, Gavin JB: Functional recovery of hearts after cardioplegia and storage in university of Wisconsin and in St. Thomas Hospital solutions. J Heart Lung Transplant 1991;10:537. Copeland JG, Griepp RB, Bieber CP, Billingham M, Schroeder JS, Hunt S, Mason J, Stinson EB, Shumway NE: Successful retransplantation of the human heart. J Thorac Cardiovasc Surg 1977;73:242. Demichov VP: Experimental transplantation of vital organs. Consultants Bureau, New York, 1962. Dreyfus G, Jebara V, Mihaileanu S, Carpentier AF: Total orthotopic heart transplantation: an alternative to the standard technique. Ann Thorac Surg 1991;52:1181. Elbeery JR, Lucke JC, Speier R, Rankin JS, Van Trigt P: Analysis of myocardial function in orthotopic cardiac allograft after prolonged storage in UW Solution. J Heart Lung Transplant 1991;10:527. Farrar DJ, Hill JD, Gray LA Jr, Pennington DG, Mc Bride LR, Pierce WS, Pae WE, Glenville B, Ross D, Galbraith TA, Zumbro GL: Heterotopic prosthetic ventricles as a bridge to cardiac transplantation. A multicenter study in 29 Patients. N Engl J Med 1988;318:333. Friedel N, Teebken M, Lemme A, Schüler S, Hetzer R: Enoximone als pharmakologisches „bridging“ zur Herztransplantation. Z Kardiol 1991;80(Suppl 4):27–22. Friedel N, Viazis P, Schiessler A, Warnecke H, Hennig E, Hetzer R: Patient selection for mechanical circulatory support as a bridge to cardiac transplantation. Int J Artif Organs 1991;14:276–279. Griep RB, Stinson EB, Clark DA, Dong E jr, Shumway NE: The cardiac donor. Surg Gynaecol Obstet 1971;133b:792. Griffith BP, Kormos RL, Hardesty RL: Heterotopic cardiac transplantation: current status. J Cardiac Surg 1987;2:283. Hardy JD, Chavez CM, Kurrus FD, Neely WA, Erascan S, Turner MD, Fabian LW, Labecki TD: Heart transplantation in man: developmental studies and report of a case. JAMA 1964;118:1132. Haverich A, Frimpong-Boateng K, Wahlers T, Schäfers HJ, Frank G, Siclari F, Ziemer G: Modifikation der Implantationstechnik bei der orthotopen Herztransplantation. Z Herz Thorax Gefäßchir 1987;1:190. Hetzer R, Warnecke H, Schüler S, Loebe M: Herztransplantation, in Hombach V (ed): Kardiovaskuläre Chirurgie. Stuttgart-New York, Schattauer, 1990, p 249. Hummel M, Warnecke H, Schüler S, Luding K, Hetzer R: Therapie der terminalen Herzinsuffizienz durch Herztransplantation. Klin Wschr 1991;69:495. Hummel M, Kuhn D, Böttner W, Forssmann WG, Hetzer R: Urodilatin, a new tool to prevent renal failure after heart transplantation. J Heart Lung Transplant 1992 (im Druck). Jamieson SW, Reitz BA, Oyer PE, Bieber CP, Stinson EB, Shumway NE: Current management of cardiac transplant recipients. Br Heart J 1979;42:703. Jamieson SW, Oyer PE, Reitz BA, Baumgartner WA, Bieber CP, Stinson EB, Shumway NE: Cardiac transplantation at Stanford. J Heart Transplant 1982;1:86. Jeevanandum V, Barr ML, Auteri JS, Sanchez JA, Ott GY, Schenkel FA, Marboe C, Smith CR, Rose EA: University of Wisconsin Solution for human donor heart preservation: initial clinical experience. Ann Thorac Surg 1991,52:1213. Kosek JC, Bieber C, Lower RR: Heart graft arteriosclerosis. Transplant Proc 1971;3:512. Kriett JM, Kaye MP: The Registry of the International Society for Heart and Lung Transplantation: Eighth Official Report 1991. J Heart Lung Transplant 1991;10:491. Loebe M, Schüler S, Warnecke H, Matheis G, Scheller E, Hetzer R: Aspergillus infection after cardiac transplantation. J Heart Transplant 1988;7:89. Loebe M, Schüler S, Warnecke H, Hetzer R: Herztransplantation im Alter — Wo liegt die Grenze? Z Kardiol 1988;77 (Suppl): 404. Loebe M, Schüler S, Spiegelsberger S, Matheis G, Warnecke H, Hetzer R: Infektionen nach Herztransplantationen. Z Herz Thorax Gefäßchir 1990;4:196. Lower RR, Stofer RC, Hurley I, Dong J, Cohn E jr, Shumway NI: Successful homotransplantation of the canine heart after anoxic preservation for seven hours. Am J Surg 1962;104:302. Magovern JA, Pennock JL, Oaks TE, Campbell DB, Burg JE, Hersey RM: Atrial natriuretic peptide in recipients of human orthotopic heart transplants. J Heart Transplant 1987;6:193. Mc Allister HA: Histologic grading of cardiac allograft rejection: a quantitative approach. J Heart Transplant 1990;9:277. Müller J, Warnecke H, Spiegelsberger S, Schüler S, Voss A, Hetzer R: Distant rejection monitoring by ECG-telephone transmission. J Heart Transplant 1990;9:82. Novitzky D, Cooper DKC, Barnard CN: The surgical technique of heterotopic heart transplantation. Ann Thorac Surg 1983;36:476. Norwood WI, Lang P, Castaneda AR: Experience with operations for hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 1981;82:511. Oaks TE, Pac WE, Miller CA, Pierce WS: Combined registry for the clinical use of mechanical ventricular assist pumps and the total artificial heart in conjunction with heart transplantation: fifth official report — 1990. J Heart Lung Transplant 1991;10:621. Oyer PE, Stinson EB, Jamieson SW, Hunt SA, Perlroth M, Billingham M, Shumway NE: Cyclosporine in cardiac transplantation: a 2 1/2 year follow-up. Transplant Proc 1983;15:2546. Park JW, Schüler S, Hetzer R, Fleck E: Wertigkeit eines nichtinvasiven Parameters der frühdiastolischen Ventrikelfunktion zur Erkennung einer Abstoßungsreaktion nach Herztransplantation. Z Kardiol 1988;77:51. Radovancevic B, Frazier OH, Gentry LO, Okereke OUJ, Cooley DA: Successful treatment of invasive Aspergillosis in heart transplant recipients. Texas Heart Inst J 1985;12:233. Reichenspurner H, Kempkes BM, Haberl R, Angermann CH, Lersch CH, Osterholzer G, Anthuber M, Weber M, Gokel JM: Patientenüberwachung nach Herztransplantation an der Universität München, Großhadern. Z Herz Thorax Gefäßchir 1987;1:79. Scheller E, Schüler S, Matheis G, Loebe M, Warnecke H, Hetzer R: Cyclosporin-A-bedingte Nephrotoxizität nach Herztransplantation. J Thorac Cardiovasc Surg 1988;36 (Suppl): 34. Schiessler A, Warnecke H, Friedel N, Hennig E, Hetzer R: Clinical use of the Berlin biventricular assist device as a bridge to transplantation. ASAIO Trans 1990;36:M706-M708. Schüler S, Hetzer R, Warnecke H, Wonigeit L, Lang W, Schober O, Borst HG: Failure of the transplanted heart without rejection — Cardiotoxic effect of Cyclosporin A. Eur Surg Res 1985;17 (Suppl I): 71. Schüler S, Schiessler A, Matheis G, Schmucker P, Warnecke H, Bücherl ES, Hennig E, Zartnack F, Ott F, Hetzer R: Überbrückung zur Herztransplantation mit Hilfe des künstlichen Herzens: Erster Erfahrungsbericht. Z Herz Thorax Gefäßchir 1987;1:194. Schüler S, Warnecke H, Wellnhofer E, Fleck E, Hetzer R: Ventrikelfunktion und Koronarmorphologie im Spätverlauf nach Herztransplantation. J Thorac Cardiovasc Surg 1987;35:34. Schüler S, Warnecke H, Matheis G, Loebe M, Scheller S, Hetzer R: The role of elevated pulmonary vascular resistance in orthotopic heart transplantation. J Heart Transplant 1988;7:89. Schüler S, Parnt R, Warnecke H, Matheis G, Hetzer R: Extended donor criteria for heart transplantation. J Heart Transplant 1988;7:326. Schüler S, Hetzer R: Immunosuppression after heart transplantation, in Wollner E, Lasczkovics A, Havel M (eds): New trends in heart transplantation. Basel, Karger, 1988, p 10. Schüler S, Warnecke H, Loebe M, Fleck E, Hetzer R: Extended donor age in cardiac transplantation. Circulation 1989;80:133. Schüler S, Matschke K, Hummel M, Loebe M, Fleck E, Park JW, Hetzer R: Spätpostoperative Transplantatfunktion und Koronarmorphologie bei Herzempfängern mit älteren Spenderherzen. J Thorac Cardiovasc Surg 1992; 40 (S.I):70–71. Sehested J, Meyer-Sabellek W, Hetzer R: Inverses zirkadianes Blutdruckprofil bei herztransplantierten Patienten, in Meyer-Sabellek W, Gotzen R (eds): Indirekte 24-Stunden-Blutdruckmessung. Darmstadt, Steinkopff, 1988, pp 143–148. Thomas FT, Szentpetery SS, Mammana RE, Wolfgang TC, Lower RR: Long-distance transportation of human hearts for transplantation. Ann Thorac Surg 1978;26:346. Warnecke H, Hetzer R, Schüler S, Goetze H, Meyer K, Süthoff U, Borst HG: Das intramyokardiale Elektrogramm zur nichtinvasiven Abstoßungsdiagnostik nach Herztransplantation. J Thorac Cardiovasc Surg 1985;33 (Suppl I): 47. Warnecke H, Schüler S, Hetzer R: Late acute rejection after cardiac transplantation: incidence and treatment. Transplant Proc 1987;19:2504. Warnecke H, Schüler S, Schliffka J, Hetzer R: Neurologic complications after heart transplantation. Transplant Proc 1987;19:2510.