Further evidence for genetic association of CACNA1C and schizophrenia: New risk loci in a Han Chinese population and a meta-analysis

Altman, 2003, Interaction revisited: the difference between two estimates, BMJ, 326, 219, 10.1136/bmj.326.7382.219 Andreasen, 1995, Symptoms, signs, and diagnosis of schizophrenia, Lancet, 346, 477, 10.1016/S0140-6736(95)91325-4 Bayer, 1999, Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “two hit hypothesis”, J. Psychiatr. Res., 33, 543, 10.1016/S0022-3956(99)00039-4 Begg, 1994, Operating characteristics of a rank correlation test for publication bias, Biometrics, 50, 1088, 10.2307/2533446 Bigos, 2010, Genetic variation in CACNA1C affects brain circuitries related to mental illness, Arch. Gen. Psychiatry, 67, 939, 10.1001/archgenpsychiatry.2010.96 Cannon, 1998, The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study, Arch. Gen. Psychiatry, 55, 67, 10.1001/archpsyc.55.1.67 Chen, 2009, Genetic structure of the Han Chinese population revealed by genome-wide SNP variation, Am. J. Hum. Genet., 85, 775, 10.1016/j.ajhg.2009.10.016 Davey Smith, 1997, Meta-analyses of randomised controlled trials, Lancet, 350, 1182, 10.1016/S0140-6736(05)63833-0 Egger, 1997, Bias in meta-analysis detected by a simple, graphical test, BMJ, 315, 629, 10.1136/bmj.315.7109.629 Gauderman, 2002, Sample size requirements for matched case–control studies of gene–environment interaction, Stat. Med., 21, 35, 10.1002/sim.973 Green, 2010, The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia, Mol. Psychiatry, 15, 1016, 10.1038/mp.2009.49 Hamshere, 2013, Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC, Mol. Psychiatry, 18, 708, 10.1038/mp.2012.67 Hori, 2012, Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals, Sci. Rep., 2, 634, 10.1038/srep00634 Krug, 2010, Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals, Neuroimage, 49, 1831, 10.1016/j.neuroimage.2009.09.028 McGuffin, 1995, Genetic basis of schizophrenia, Lancet, 346, 678, 10.1016/S0140-6736(95)92285-7 Nyegaard, 2010, CACNA1C (rs1006737) is associated with schizophrenia, Mol. Psychiatry, 15, 119, 10.1038/mp.2009.69 Owen, 2010, Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia, Arch. Gen. Psychiatry, 67, 667, 10.1001/archgenpsychiatry.2010.69 Radua, 2013, The impact of CACNA1C allelic variation on effective connectivity during emotional processing in bipolar disorder, Mol. Psychiatry, 18, 526, 10.1038/mp.2012.61 Ripke, 2011, Genome-wide association study identifies five new schizophrenia loci, Nat. Genet., 43, 969, 10.1038/ng.940 Saha, 2005, A systematic review of the prevalence of schizophrenia, PLoS Med., 2, e141, 10.1371/journal.pmed.0020141 Shi, 2005, SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci, Cell Res., 15, 97, 10.1038/sj.cr.7290272 Smoller, 2013, Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis, Lancet, 381, 1371, 10.1016/S0140-6736(12)62129-1 Soeiro-de-Souza, 2013, The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder, Acta Psychiatr. Scand., 128, 362, 10.1111/acps.12073 Strohmaier, 2013, The psychiatric vulnerability gene CACNA1C and its sex-specific relationship with personality traits, resilience factors and depressive symptoms in the general population, Mol. Psychiatry, 18, 607, 10.1038/mp.2012.53 Sullivan, 2003, Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies, Arch. Gen. Psychiatry, 60, 1187, 10.1001/archpsyc.60.12.1187 Thimm, 2011, Effects of a CACNA1C genotype on attention networks in healthy individuals, Psychol. Med., 41, 1551, 10.1017/S0033291710002217 Wang, 2011, The association of genetic variation in CACNA1C with structure and function of a frontotemporal system, Bipolar Disord., 13, 696, 10.1111/j.1399-5618.2011.00963.x Wessa, 2010, The CACNA1C risk variant for bipolar disorder influences limbic activity, Mol. Psychiatry, 15, 1126, 10.1038/mp.2009.103 Woodward, 2005 Xu, 2009, Genomic dissection of population substructure of Han Chinese and its implication in association studies, Am. J. Hum. Genet., 85, 762, 10.1016/j.ajhg.2009.10.015 Yue, 2011, Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2, Nat. Genet., 43, 1228, 10.1038/ng.979 Zhang, 2012, The effects of CACNA1C gene polymorphism on spatial working memory in both healthy controls and patients with schizophrenia or bipolar disorder, Neuropsychopharmacology, 37, 677, 10.1038/npp.2011.242