FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
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Arico, 2001, The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway, J. Biol. Chem., 276, 35243, 10.1074/jbc.C100319200
Barthel, 2005, FoxO proteins in insulin action and metabolism, Trends Endocrinol. Metab., 16, 183, 10.1016/j.tem.2005.03.010
Bechet, 2005, Lysosomal proteolysis in skeletal muscle, Int. J. Biochem. Cell Biol., 37, 2098, 10.1016/j.biocel.2005.02.029
Beehler, 2006, Reduction of skeletal muscle atrophy by a proteasome inhibitor in a rat model of denervation, Exp. Biol. Med. (Maywood), 231, 335, 10.1177/153537020623100315
Bodine, 2001, Identification of ubiquitin ligases required for skeletal muscle atrophy, Science, 294, 1704, 10.1126/science.1065874
Brunet, 1999, Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor, Cell, 96, 857, 10.1016/S0092-8674(00)80595-4
Cuervo, 2000, Unique properties of lamp2a compared to other lamp2 isoforms, J. Cell Sci., 113, 4441, 10.1242/jcs.113.24.4441
Du, 2004, Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions, J. Clin. Invest., 113, 115, 10.1172/JCI18330
Furuno, 1990, Role of different proteolytic systems in the degradation of muscle proteins during denervation atrophy, J. Biol. Chem., 265, 8550, 10.1016/S0021-9258(19)38923-9
Glass, 2005, Skeletal muscle hypertrophy and atrophy signaling pathways, Int. J. Biochem. Cell Biol., 37, 1974, 10.1016/j.biocel.2005.04.018
Glickman, 2002, The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction, Physiol. Rev., 82, 373, 10.1152/physrev.00027.2001
Gronostajski, 1984, The role of increased proteolysis in the atrophy and arrest of proliferation in serum-deprived fibroblasts, J. Cell. Physiol., 121, 189, 10.1002/jcp.1041210124
Iwata, 2005, HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin, J. Biol. Chem., 280, 40282, 10.1074/jbc.M508786200
Juhasz, 2007, Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body, Cell Death Differ., 14, 1181, 10.1038/sj.cdd.4402123
Kandarian, 2006, Intracellular signaling during skeletal muscle atrophy, Muscle Nerve, 33, 155, 10.1002/mus.20442
Kisselev, 2001, Proteasome inhibitors: from research tools to drug candidates, Chem. Biol., 8, 739, 10.1016/S1074-5521(01)00056-4
Klionsky, 2003, A unified nomenclature for yeast autophagy-related genes, Dev. Cell, 5, 539, 10.1016/S1534-5807(03)00296-X
Knecht, 1984, Regulation of lysosomal autophagy in transformed and non-transformed mouse fibroblasts under several growth conditions, Exp. Cell Res., 154, 224, 10.1016/0014-4827(84)90682-7
Kramerova, 2005, Calpain 3 participates in sarcomere remodeling by acting upstream of the ubiquitin-proteasome pathway, Hum. Mol. Genet., 14, 2125, 10.1093/hmg/ddi217
Lecker, 2004, Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression, FASEB J., 18, 39, 10.1096/fj.03-0610com
Lecker, 2006, Protein degradation by the ubiquitin-proteasome pathway in normal and disease states, J. Am. Soc. Nephrol., 17, 1807, 10.1681/ASN.2006010083
Levine, 2004, Development by self-digestion: molecular mechanisms and biological functions of autophagy, Dev. Cell, 6, 463, 10.1016/S1534-5807(04)00099-1
Liang, 1999, Induction of autophagy and inhibition of tumorigenesis by beclin 1, Nature, 402, 672, 10.1038/45257
Mammucari, 2007, FoxO3 controls autophagy in skeletal muscle in vivo, Cell Metab., 6, 10.1016/j.cmet.2007.11.001
Meijer, 2006, Signalling and autophagy regulation in health, aging and disease, Mol. Aspects Med., 27, 411, 10.1016/j.mam.2006.08.002
Melendez, 2003, Autophagy genes are essential for dauer development and life-span extension in C. elegans, Science, 301, 1387, 10.1126/science.1087782
Mizushima, 2001, Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells, J. Cell Biol., 152, 657, 10.1083/jcb.152.4.657
Mizushima, 2004, In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker, Mol. Biol. Cell, 15, 1101, 10.1091/mbc.E03-09-0704
Mortimore, 1983, Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding, Proc. Natl. Acad. Sci. USA, 80, 2179, 10.1073/pnas.80.8.2179
Ohsumi, 2001, Molecular dissection of autophagy: two ubiquitin-like systems, Nat. Rev. Mol. Cell Biol., 2, 211, 10.1038/35056522
Petiot, 2000, Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells, J. Biol. Chem., 275, 992, 10.1074/jbc.275.2.992
Rando, 1994, Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy, J. Cell Biol., 125, 1275, 10.1083/jcb.125.6.1275
Rock, 1994, Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules, Cell, 78, 761, 10.1016/S0092-8674(94)90462-6
Sacheck, 2004, IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1, Am. J. Physiol. Endocrinol. Metab., 287, E591, 10.1152/ajpendo.00073.2004
Sacheck, 2007, Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases, FASEB J., 21, 140, 10.1096/fj.06-6604com
Sandri, 2004, Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy, Cell, 117, 399, 10.1016/S0092-8674(04)00400-3
Sandri, 2006, PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription, Proc. Natl. Acad. Sci. USA, 103, 16260, 10.1073/pnas.0607795103
Sarkar, 2007, Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein, J. Biol. Chem., 282, 5641, 10.1074/jbc.M609532200
Schiaffino, 1972, Studies on the effect of denervation in developing muscle. II. The lysosomal system, J. Ultrastruct. Res., 39, 1, 10.1016/S0022-5320(72)80002-9
Scott, 1998, Delivery of proteins and organelles to the vacuole from the cytoplasm, Curr. Opin. Cell Biol., 10, 523, 10.1016/S0955-0674(98)80068-9
Seglen, 1983, Inhibitors of lysosomal function, Methods Enzymol., 96, 737, 10.1016/S0076-6879(83)96063-9
Seglen, 1982, 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes, Proc. Natl. Acad. Sci. USA, 79, 1889, 10.1073/pnas.79.6.1889
Solomon, 1996, Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts, J. Biol. Chem., 271, 26690, 10.1074/jbc.271.43.26690
Stitt, 2004, The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors, Mol. Cell, 14, 395, 10.1016/S1097-2765(04)00211-4
Tassa, 2003, Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes, Biochem. J., 376, 577, 10.1042/bj20030826
Woo, 1992, Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification, J. Antibiot. (Tokyo), 45, 1108, 10.7164/antibiotics.45.1108
Yamamoto, 2006, Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway, J. Cell Biol., 172, 719, 10.1083/jcb.200510065