Flavonoids and the inhibition of PKC and PI 3-kinase
Tóm tắt
Từ khóa
Tài liệu tham khảo
Afanas’ev, 1989, Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation, Biochem Pharmac, 38, 1763, 10.1016/0006-2952(89)90410-3
Agullo, 1996, Comparative effects of flavonoids on the growth, viability and metabolism of a colonic adenocarcinoma cell line (HT29 cells), Cancer Lett, 105, 61, 10.1016/0304-3835(96)04262-0
Agullo, 1997, Relationship between flavonoid structure and inhibition of phosphatidylinositol-3 kinase, Biochem Pharmac, 53, 1649, 10.1016/S0006-2952(97)82453-7
Akiyama, 1987, Genistein, a specific inhibitor of tyrosine-specific protein kinases, J Biol Chem, 262, 5592, 10.1016/S0021-9258(18)45614-1
Bacqueville, 1998, Phosphatidylinositol 3-kinase inhibitors block aortic smooth muscle cell proliferation in mid-late G1 phase, Biochem Biophys Res Commun, 244, 630, 10.1006/bbrc.1997.7885
Birt, 1997, Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid, Anticancer Res, 17, 85
Blumber, 1988, Protein kinase C as the receptor of phorbol ester tumor promoter, Cancer Res, 48, 1
Csokay, 1997, Molecular mechanisms in the antiproliferative action of quercetin, Life Sci, 24, 2157, 10.1016/S0024-3205(97)00230-0
Deschner, 1991, Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia, Carcinogenesis, 12, 1193, 10.1093/carcin/12.7.1193
End, 1987, Nonselective inhibition of mammalian protein kinases by flavonoids in vitro, Res Commun Chem Pathol Pharmac, 56, 75
Ferriola, 1989, Protein kinase C inhibition by plants flavonoids, Biochem Pharmac, 38, 1617, 10.1016/0006-2952(89)90309-2
Fishman, 1998, The role of protein kinase C in G1 and G2/M phases of the cell cycle, Int J Oncol, 12, 181
Fujiki, 1986, Inhibition of tumor promotion by flavonoids, Prog Clin Biol Res, 213, 429
Hawkins, 1997, Signalling via phosphoinositide 3OH kinase, Biochem Soc Trans, 25, 1147, 10.1042/bst0251147
Herrera, 1996, Effects of flavonoids on rat aortic smooth muscle contractility, Gen Pharmac, 27, 273, 10.1016/0306-3623(95)02010-1
Hertog, 1996, Epidemiological evidence on potential health properties of flavonoids, Proc Nutr Soc, 55, 385, 10.1079/PNS19960037
Hertog, 1993, Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands, Nutr Cancer, 20, 21, 10.1080/01635589309514267
Hirano, 1994, Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL 60 cells, Life Sci, 55, 1061, 10.1016/0024-3205(94)00641-5
Hollman, 1998, Bioavaibility and health effects of dietary flavonols in man, Arch Toxicol, 237, 10.1007/978-3-642-46856-8_21
Hollman, 1996, Absorption and disposition kinetics of the dietary antioxidant quercetin in man, Free Radical Biol Med, 21, 703, 10.1016/0891-5849(96)00129-3
Huang, 1996, Inhibitions of protein kinase C and proto-oncogene expressions in NIH 3T3 cells by apigenin, Eur J Cancer, 32A, 146, 10.1016/0959-8049(95)00540-4
Ireton, 1996, A role for PI 3-kinase in bacterial invasion, Science, 274, 780, 10.1126/science.274.5288.780
Kang, 1997, Studies on the inhibitory effects of quercetin on the growth of HL60 leukemia cells, Biochem Pharmac, 54, 1013, 10.1016/S0006-2952(97)00260-8
Knekt, 1997, Dietary flavonoids and the risk of lung cancer and other malignant neoplasms, Am J Epidemiol, 146, 223, 10.1093/oxfordjournals.aje.a009257
Korkina, 1997, Antioxidant and chelating properties of flavonoids, Adv Pharmac, 38, 151, 10.1016/S1054-3589(08)60983-7
Kovacsovics, 1995, Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation, J Biol Chem, 270, 11358, 10.1074/jbc.270.19.11358
Kuo, 1996, Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells, Cancer Lett, 110, 41, 10.1016/S0304-3835(96)04458-8
Lee, 1994, Mechanism of quercetin-induced suppression and delay of heat shock gene expression and thermotolerance development in HT-29 cells, Mol Cell Biochem, 137, 141, 10.1007/BF00944076
Lepley, 1997, Induction of P21/WAF 1 and G1 cell-cycle arrest by the chemopreventive agent apigenin, Mol Carcinog, 19, 74, 10.1002/(SICI)1098-2744(199707)19:2<74::AID-MC2>3.0.CO;2-L
Lepley, 1996, The chemopreventive flavonoid apigenin induces G2/M arrest in keratynocytes, Carcinogenesis, 17, 2367, 10.1093/carcin/17.11.2367
Lewis, 1996, Protein kinase C regulates αvβ5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation, J Cell Biol, 134, 1323, 10.1083/jcb.134.5.1323
Livneh, 1997, Linking protein kinase C to cell-cycle control, Eur J Biochem, 248, 1, 10.1111/j.1432-1033.1997.t01-4-00001.x
Middleton, 1993, 619
Nishizuka, 1984, The role of protein kinase C in cell surface signal transduction and tumour, Nature, 308, 693, 10.1038/308693a0
Nishizuka, 1986, Studies and perspectives of protein kinase C, Science, 233, 305, 10.1126/science.3014651
Nishizuka, 1992, Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C, Science, 258, 607, 10.1126/science.1411571
Nishizuka, 1995, Protein kinase C and lipid signaling for sustained cellular responses, FASEB J, 9, 484, 10.1096/fasebj.9.7.7737456
Paganga, 1997, The identification of flavonoids as glycosides in human plasma, FEBS Lett, 401, 78, 10.1016/S0014-5793(96)01442-1
Rameh, 1995, Phosphatidylinositol(3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins, Cell, 83, 821, 10.1016/0092-8674(95)90195-7
Rice-Evans, 1996, Structure-antioxidant activity relationships of flavonoids and phenolic acids, Free Radical Biol Med, 20, 933, 10.1016/0891-5849(95)02227-9
Scambia, 1993, Quercetin induces type-II estrogen-binding sites in estrogen-receptor negative (MDA6MB231) and estrogen-receptor-positive (MCF7) human breast-cancer cell lines, Int J Cancer, 54, 462, 10.1002/ijc.2910540318
Scambia, 1996, Antiproliferative effect of silybin on gynaecological malignacies, Eur J Cancer, 32A, 877, 10.1016/0959-8049(96)00011-1
Takai, 1977, Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues, J Biol Chem, 252, 7603, 10.1016/S0021-9258(17)41009-X
Toker, 1997, Signalling through the lipid products of phosphoinositide-OH kinase, Nature, 387, 673, 10.1038/42648
Vanhaesebroeck, 1997, Phosphoinositide 3-kinases, Trends Biochem Sci, 22, 267, 10.1016/S0968-0004(97)01061-X
Verma, 1988, Inhibition of 7,12-dimethylbenz(a)anthracene and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin, Cancer Res, 48, 5754
Vlahos, 1994, A specific inhibitor of phosphatidyl inositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002), J Biol Chem, 269, 5241, 10.1016/S0021-9258(17)37680-9
Wei, 1994, Induction of apoptosis by quercetin, Cancer Res, 54, 4952