Ferulic acid reverses P-glycoprotein-mediated multidrug resistance via inhibition of PI3K/Akt/NF-κB signaling pathway

The Journal of Nutritional Biochemistry - Tập 63 - Trang 62-71 - 2019
Ganesan Muthusamy1, Srithar Gunaseelan1, Nagarajan Rajendra Prasad1
1Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608002, Tamilnadu, India

Tài liệu tham khảo

Genovese, 2017, Not only P-glycoprotein: amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins, Drug Resist Updat, 32, 23, 10.1016/j.drup.2017.10.003 Ling, 1974, Reduced permeability in CHO cells as a mechanism of resistance to colchicine, J Cell Physiol, 83, 103, 10.1002/jcp.1040830114 Vauthier, 2017, Targeted pharmacotherapies for defective ABC transporters, Biochem Pharmacol, 136, 1, 10.1016/j.bcp.2017.02.020 Szwed, 2014, Relationship between therapeutic efficacy of doxorubicin-transferrin conjugate and expression of P-glycoprotein in chronic erythromyeloblastoid leukemia cells sensitive and resistant to doxorubicin, Cell Oncol, 37, 421, 10.1007/s13402-014-0205-5 Jagadeeshan, 2017, Solanum nigrum unripe fruit fraction attenuates adriamycin resistance by down-regulating multi-drug resistance protein (Mdr)-1 through Jak-STAT pathway, BMC Complement Altern Med, 17, 370, 10.1186/s12906-017-1872-3 Ge, 2017, The down-regulation of SLC7A11 enhances ROS induced P-gp over-expression and drug resistance in MCF-7 breast cancer cells, Sci Rep, 7, 3791, 10.1038/s41598-017-03881-9 He, 2018, Dexmedetomidine impairs P-glycoprotein-mediated efflux function in L02 cells via the adenosine 5′-monophosphate-activated protein kinase/nuclear factor-κB pathway, Mol Med Rep, 17, 5049 Tsou, 2016, Gain-of-function p53 mutant with 21-bp deletion confers susceptibility to multidrug resistance in MCF-7 cells, Int J Mol Med, 37, 233, 10.3892/ijmm.2015.2406 Sims, 2013, Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1, PLoS One, 8, 10.1371/journal.pone.0055509 Loaiza, 2016, Nuclear transcription factor kappa B downregulation reduces chemoresistance in bone marrow-derived cells through P-glycoprotein modulation, Arch Med Res, 47, 78, 10.1016/j.arcmed.2016.05.004 Requenez-Contreras, 2017, MiR-138 indirectly regulates the MDR1 promoter by NF-κB/p65 silencing, Biochem Biophys Res Commun, 484, 648, 10.1016/j.bbrc.2017.01.168 Shi, 2015, Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-siRNA, World J Gastroenterol, 21, 10.3748/wjg.v21.i45.12814 Zeligs, 2016, Molecular pathways: the balance between Cancer and the immune system challenges the therapeutic specificity of targeting nuclear factor-κB signaling for cancer treatment, Clin Cancer Res, 22, 4302, 10.1158/1078-0432.CCR-15-1374 Solt, 2008, The IkappaB kinase complex: master regulator of NF-kappaB signaling, Immunol Res, 42, 3, 10.1007/s12026-008-8025-1 Dong, 2017, Activation of phosphatidylinositol 3-kinase/AKT/snail signaling pathway contributes to epithelial-mesenchymal transition-induced multi-drug resistance to sorafenib in hepatocellular carcinoma cells, PLoS One, 12, 10.1371/journal.pone.0185088 Joshi, 2017, Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer, Eur J Med Chem, 138, 273, 10.1016/j.ejmech.2017.06.047 Kumar, 2014, Potential applications of ferulic acid from natural sources, Biotechnol Rep (Amst), 4, 86, 10.1016/j.btre.2014.09.002 Hole, 2012, Synergistic and suppressive effects of dietary phenolic acids and other phytochemicals from cereal extracts on nuclear factor kappa B activity, Food Chem, 133, 969, 10.1016/j.foodchem.2012.02.017 Jung, 2009, Suppression of age-related renal changes in NF-κB and its target gene expression by dietary ferulate, J Nutr Biochem, 20, 378, 10.1016/j.jnutbio.2008.04.008 Manoharan, 2014, Modulating effect of ferulic acid on NF-kB, COX-2 and VEGF expression pattern during 7, 12-dimethylbenz (a) anthracene induced oral carcinogenesis, Open Nutraceuticals J, 7, 33, 10.2174/1876396001407010033 Manikandan, 2014, Ameliorative effect of ferulic acid against renal injuries mediated by nuclear factor-kappaB during glycerol-induced nephrotoxicity in Wistar rats, Ren Fail, 36, 154, 10.3109/0886022X.2013.835223 Das, 2014, Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model, PLoS One, 9, 10.1371/journal.pone.0097599 Muthusamy, 2016, Ferulic acid reverses ABCB1-mediated paclitaxel resistance in MDR cell lines, Eur J Pharmacol, 786, 194, 10.1016/j.ejphar.2016.05.023 Mosmann, 1983, Rapid colorimetric assay for cellular growth and survival: applicationto proliferation and cytotoxicity assays, J Immunol Methods, 65, 55, 10.1016/0022-1759(83)90303-4 entires-Alj, 2003, NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells, Oncogene, 22, 90, 10.1038/sj.onc.1206056 Bednarski, 2008, Active roles for inhibitory kappaB kinases alpha and beta in nuclear factor-kappaB-mediated chemoresistance to doxorubicin, Mol Cancer Ther, 7, 1827, 10.1158/1535-7163.MCT-08-0321 Wang, 2015, Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP-responsive element transcriptional activity, Tumor Biol, 36, 9499, 10.1007/s13277-015-3636-3 Suttana, 2010, Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols, Mol Cancer, 9, 99, 10.1186/1476-4598-9-99 Xia, 2015, Alopecurone B reverses doxorubicin-resistant human osteosarcoma cell line by inhibiting P-glycoprotein and NF-kappa B signaling, Phytomedicine, 22, 344, 10.1016/j.phymed.2014.12.011 Shen, 1986, Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification, Science, 232, 643, 10.1126/science.3457471 Reddig, 2015, Assessment of modulated cytostatic drug resistance by automated γH2AX analysis, Cytometry A, 87, 724, 10.1002/cyto.a.22667 Yang, 2014, Doxorubicin, DNA torsion, and chromatin dynamics, Biochim Biophys Acta, 1845, 84 Xi, 2016, CD133 and DNA-PK regulate MDR1 via the PI3K-or Akt-NF-κB pathway in multidrug-resistant glioblastoma cells in vitro, Oncogene, 35, 241, 10.1038/onc.2015.78 Zhou, 1997, NF-kappaB-mediated induction of mdr1b expression by insulin in rat hepatoma cells, J Biol Chem, 272, 15174, 10.1074/jbc.272.24.15174 Montazami, 2015, New insights into the mechanisms of multidrug resistance in cancers, Cell Mol Biol, 61, 70 Wang, 2016, Ferulic acid inhibits proliferation and promotes apoptosis via blockage of PI3K/Akt pathway in osteosarcoma cell, Am J Transl Res, 8, 968 Song, 2016, Ferulic acid against cyclophosphamide-induced heart toxicity in mice by inhibiting NF-κB pathway, Evid Based Complement Alternat Med, 2016, 1261270, 10.1155/2016/1261270 Lopes-Rodrigues, 2016, Curcumin as a modulator of P-glycoprotein in Cancer: challenges and perspectives, Pharmaceuticals (Basel), 9, 10.3390/ph9040071