Evaluation of a prostacyclin analog in prevention of pulmonary oxygen toxicity

Clark, 1971, Pulmonary oxygen toxicity: a review, Pharmacol Rev, 23, 37 Hageman, 1986, The early involvement of pulmonary prostaglandins in hyperoxic lung injury, Prostaglandins Leukotrienes and Medicine, 25, 105, 10.1016/0262-1746(86)90058-2 Holtzman, 1989, The role of eicosanoids in relative newborn tolerance to hyperoxia, Prostaglandins, 37, 481, 10.1016/0090-6980(89)90097-X Holtzman, 1989, Loss of oxygen tolerance in newborn rabbits: relationship to changes in eicosanoid and antioxidant levels, Pediatr Pulmonol, 7, 200, 10.1002/ppul.1950070404 Vane, 1982, Prostacyclin: a hormone with therapeutic potential, J Endocrinol, 95, 3P Schror, 1981, The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK 36 374) — eqipotent to PGI2 in vitro, Naunyn-Schmiedeberg's Arch Pharmacol, 316, 252, 10.1007/BF00505658 Simpson, 1987, Iloprost inhibits neutrophil function in vitro and in vivo and limits experimental infarct size in canine heart, Circ Res, 60, 666, 10.1161/01.RES.60.5.666 Gryglewski, 1987, The effect of six prostaglandins, prostacyclin and iloprost on generation of superoxide anions by human polymorphonuclear leukocytes stimulated by zymosan or formyl-methionyl-leucyl-phenylalanine, Biochem Pharmacol, 36, 4209, 10.1016/0006-2952(87)90660-5 Whittle, 1985, Platelet actions of stable carbacyclic analogues of prostacyclin, Circulation, 72, 1219, 10.1161/01.CIR.72.6.1219 Schror, 1981, Beneficial effects of a new carbacyclin derivative, ZK 36 374, in acute myocardial ischemia, J Pharmacol Exp Ther, 219, 243 Bradford, 1976, A rapid and sensitive method for quantitation of microgram quantities of protein using the principles of protein-dye binding, Anal Biochem, 72, 248, 10.1016/0003-2697(76)90527-3 Crapo J D. Morphologic changes in pulmonary oxygen toxicity. Ann Rev Physiol 48: 721–731. Adamson, 1990, Epithelial cell-fibroblast interactions in lung injury and repair, Am J Pathol, 137, 385 McCord, 1978, The biology and pathology of oxygen radicals, Ann Int Med, 89, 122, 10.7326/0003-4819-89-1-122 Ford-Hutchinson, 1980, Leukotriene B4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes, Nature, 286, 264, 10.1038/286264a0 Jackson, 1986, Production of arachidonic acid metabolites by endothelial cells in hyperoxia, J Appl Physiol, 61, 584, 10.1152/jappl.1986.61.2.584 Taniguchi, 1986, The role of leukotriene B4 in the genesis of oxygen toxicity in the lung, Am Rev Respir Dis, 133, 805 Boxer, 1980, Inhibition of polymorphonuclear leukocyte adherence by prostacyclin, J Lab Clin Med, 95, 672 Fantone, 1983, Prostaglandin E1 and prostaglandin I2 modulation of superoxide production by human neutrophils, Biochem Biophys Res Comm, 113, 506, 10.1016/0006-291X(83)91754-0 Smith, 1984, Early and late administration of a PGI2-analogue, ZK 36 374 (iloprost): effects on myocardial preservation, collateral blood flow and infarct size, Cardiovascular Res, 18, 163, 10.1093/cvr/18.3.163 Fantone, 1984, Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production, Am J Pathol, 115, 9 Moncada, 1976, An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation, Nature, 263, 663, 10.1038/263663a0 Leffer, 1981, Perinatal pulmonary prostaglandin production, Am J Physiol, 241, H756