Ethanol sensitivity of the GABAA receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit

Neuron - Tập 7 Số 1 - Trang 27-33 - 1991
Keith A. Wafford1, Donald M. Burnett1, Nancy J. Leidenheimer1, David R. Burt2, Jia Bei Wang2, Paulo Kofuji3, Thomas V. Dunwiddie1, R. Adron Harris4, James M. Sikela1
1Department of Pharmacology University, Colorado Health Sciences Center, Veterans Administration Medical Center Denver
2Department of Pharmacology University, Maryland School of Medicine Baltimore
3Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland 21201 USA
4Department of Pharmacology University of Colorado Health Sciences Center and Veterans Administration Medical Center Denver, Colorado 80262, USA

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Aguayo, 1990, Ethanol potentiates the GABAA-activated CI-current in mouse hippocampal and cortical neurons, Fur. J. Pharmacol., 187, 127

Allan, 1986, γ-Aminobutyric acid and ethanol actions: neurochemical studies of long-sleep and shortsleep mice, Life Sci., 39, 2005, 10.1016/0024-3205(86)90324-3

Allan, 1991, Ethanol-induced changes in chloride flux are mediated by both GABAA and GABA,, receptors, Alcoholism: Clin. Exp. Res., 15, 233, 10.1111/j.1530-0277.1991.tb01862.x

Deitrich, 1989, Mechanism of action of ethanol: initial central nervous system actions, Pharmacol. Rev., 41, 491

Givens, 1990, Site-specific enhancement of γ-aminobutyric acid-mediated inhibition of neural activity by ethanol in the rat medial septal area, J. Pharmacol. Exp. Ther., 254, 528

Harland, 1985, Translation of mRNA injected into Xenopus oocytes is specifically inhibited byantisense RNA, J. Cell Biol., 101, 1094, 10.1083/jcb.101.3.1094

Harris, 1990, Distinct actions of alcohols, barbiturates and benzodiazepines on GABA-activated chloride channels, Alcohol, 7, 273, 10.1016/0741-8329(90)90017-7

Harris, 1989, Alcohol intoxication: ion channels and genetics, FASEB J., 3, 1689, 10.1096/fasebj.3.6.2467834

Harris, 1989, Genetic differences in coupling of benzodiazepine receptors to chloride channels, Brain Res., 490, 26, 10.1016/0006-8993(89)90426-5

Hoshi, 1990, Biophysical and molecular mechanisms of shaker potassium channel activation, Science, 250, 533, 10.1126/science.2122519

Keir, 1991, The cDNA sequence and chromosomal location of the murine GABAA α1 receptor gene, Genomics, 9, 390, 10.1016/0888-7543(91)90272-G

Kofuji, 1991, Generation of two forms of the y-aminobutyric acid receptorA y2-subunit in mice by alternative splicing, J. Neurochem., 56, 713, 10.1111/j.1471-4159.1991.tb08209.x

Leidenheimer, 1991, GABAA receptor phosphorylation: multiple sites, actions andartifacts, Trends Pharmacol. Sci., 12, 84, 10.1016/0165-6147(91)90509-Q

Lin, 1991, Ethanol potentiation of GABA-induced electrophysiological responses in cerebellum: requirement for catecholamine modulation, Neurosci. Lett., 122, 154, 10.1016/0304-3940(91)90846-L

Mehta, 1988, Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves γ-aminobutyric acidA-gated chloride channels, J. Pharmacol. Exp. Ther., 246, 558

Mody, 1991, Halothane enhances tonic neuronal inhibition by elevating intracellular calcium, Brain Res., 538, 319, 10.1016/0006-8993(91)90447-4

Moss, 1991, Characterization of recombinant GABAA receptors produced in transfected cells from murine α1, β1, and γ2 subunit cDNAs, Neurosci. Lett., 123, 265, 10.1016/0304-3940(91)90947-R

Olsen, 1990, Molecular biology of GABA-, receptors, FASEB J., 4, 1469, 10.1096/fasebj.4.5.2155149

Pritchett, 1989, Importance of a novel GABA, subunit for benzodiazepine pharmacology, Nature, 338, 582, 10.1038/338582a0

Sigel, 1990, The effect of subunit composition of rat brain GABA, receptors on channel function, Neuron, 5, 703, 10.1016/0896-6273(90)90224-4

Sommer, 1990, Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS, Science, 249, 1580, 10.1126/science.1699275

Sumikawa, 1988, Repression of isotonic acetylcholine receptor expression by antisense RNAs and an oligonucleotide, 85, 1302

Suzdak, 1986, Ethanol stimulates γ-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes, 83, 4071

Wafford, 1989, Calcium-dependent chloride currents elicited by injection of ethanol into Xenopus oocytes, Brain Res., 505, 215, 10.1016/0006-8993(89)91445-5

Wafford, 1990, Genetic differences in the ethanol sensitivity of GABAA receptors expressed in Xenopus oocytes, Science, 249, 291, 10.1126/science.1695761

White, 1990, Ethanol inhibits NMDA-activated current but does not alter GABA-activated current in an isolated adult mammalian neuron, Brain Res., 507, 332, 10.1016/0006-8993(90)90292-J

Whiting, 1990, Another mechanism for creating diversity in γ-aminobutyrate type A receptors: RNA splicing directs expression of two forms of γ2 subunit, one of which contains a protein kinase C phosphorylation site, 87, 9966

Wilson-Shaw, 1991, A novel y subunit of the GABAA receptor identified using the polymerase chain reaction, FEBS Lett., 284, 211, 10.1016/0014-5793(91)80687-X