William T. Friedewald1, Robert I. Levy1, Donald S. Fredrickson1
1Biometrics Research Branch (W.T.F.) and the Molecular Disease Branch (R.I.L. and D.S.F.), National Heart and Lung Institute, 9000 Rockville Pike, Bethesda, Md. 20014
Tóm tắt
Abstract
A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol concentrations, none of which requires the use of the preparative ultracentrifuge. Comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99, depending on the patient population compared.
