1Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Canada
2St. Joseph’s Healthcare Hamilton, McMaster University, Hamilton, Canada
3Department of Medicine, McMaster University, Hamilton, Canada
4Interdepartmental Division of Critical Care, Hamilton Health Sciences, Hamilton, Canada
5Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
6St Michael's Hospital, University of Toronto, Toronto, Canada
7Intensive Care Unit, Monash Medical Centre, Melbourne, Australia.
8Department of Critical Care Medicine, Queens University Kingston, Kingston, Canada
9University Health Network, University of Toronto, Toronto, Canada
10Mount Sinai Hospital, University of Toronto, Toronto, Canada
11Division of Critical Care, Department of Medicine, University of British Columbia, Vancouver, Canada
12Duke Clinical Research Institute, Duke University, Durham, USA
13Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Québec, Canada
14Centre for Evaluation of Medicines, St. Joseph’s Healthcare Hamilton, Hamilton, Canada
