Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colonized by P. aeruginosa

Cystic Fibrosis Foundation Patient Registry. Annual Data Report. 2010.

Burns, 2001, Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis, J Infect Dis, 183, 444, 10.1086/318075

Gibson, 2003, Pathophysiology and management of pulmonary infections in cystic fibrosis, Am J Respir Crit Care Med, 168, 918, 10.1164/rccm.200304-505SO

Rosenfeld, 2003, Pseudomonas acquisition in young patients with cystic fibrosis: pathophysiology, diagnosis, and management, Curr Opin Pulm Med, 9, 492, 10.1097/00063198-200311000-00008

Li, 2005, Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis, JAMA, 293, 581, 10.1001/jama.293.5.581

Johansen, 1992, Seasonal onset of initial colonisation and chronic infection with Pseudomonas aeruginosa in patients with cystic fibrosis in Denmark, Thorax, 47, 109, 10.1136/thx.47.2.109

Doring, 2000, Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus, Eur Respir J, 16, 749, 10.1034/j.1399-3003.2000.16d30.x

Lee, 2003, Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients, J Cyst Fibros, 2, 29, 10.1016/S1569-1993(02)00141-8

Nixon, 2001, Clinical outcome after early Pseudomonas aeruginosa infection in cystic fibrosis, J Pediatr, 138, 699, 10.1067/mpd.2001.112897

Kerem, 1990, Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with Pseudomonas aeruginosa, J Pediatr, 116, 714, 10.1016/S0022-3476(05)82653-8

Kosorok, 2001, Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition, Pediatr Pulmonol, 32, 277, 10.1002/ppul.2009.abs

Pamukcu, 1995, Effects of Pseudomonas aeruginosa colonization on lung function and anthropometric variables in children with cystic fibrosis, Pediatr Pulmonol, 19, 10, 10.1002/ppul.1950190103

Demko, 1995, Gender differences in cystic fibrosis: Pseudomonas aeruginosa infection, J Clin Epidemiol, 48, 1041, 10.1016/0895-4356(94)00230-N

Doring, 2004, Early intervention and prevention of lung disease in cystic fibrosis: a European consensus, J Cyst Fibros, 3, 67, 10.1016/j.jcf.2004.03.008

Bendiak, 2009, The approach to Pseudomonas aeruginosa in cystic fibrosis, Semin Respir Crit Care Med, 30, 587, 10.1055/s-0029-1238917

Frederiksen, 1999, Changing epidemiology of Pseudomonas aeruginosa infection in Danish cystic fibrosis patients (1974–1995), Pediatr Pulmonol, 28, 159, 10.1002/(SICI)1099-0496(199909)28:3<159::AID-PPUL1>3.0.CO;2-1

Ballmann, 1998, Long-term follow up of changes in FEV1 and treatment intensity during Pseudomonas aeruginosa colonisation in patients with cystic fibrosis, Thorax, 53, 732, 10.1136/thx.53.9.732

FitzSimmons, 1993, The changing epidemiology of cystic fibrosis, J Pediatr, 122, 1, 10.1016/S0022-3476(05)83478-X

Littlewood, 1985, Nebulised colomycin for early pseudomonas colonisation in cystic fibrosis, Lancet, 1, 865, 10.1016/S0140-6736(85)92222-6

Steinkamp, 1989, Treatment of pseudomonas aeruginosa colonisation in cystic fibrosis, Arch Dis Child, 64, 1022, 10.1136/adc.64.7.1022

Valerius, 1991, Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment, Lancet, 338, 725, 10.1016/0140-6736(91)91446-2

Vazquez, 1993, Early treatment of Pseudomonas aeruginosa colonization in cystic fibrosis, Acta Paediatr, 82, 308, 10.1111/j.1651-2227.1993.tb12668.x

Wiesemann, 1998, Placebo-controlled, double-blind, randomized study of aerosolized tobramycin for early treatment of Pseudomonas aeruginosa colonization in cystic fibrosis, Pediatr Pulmonol, 25, 88, 10.1002/(SICI)1099-0496(199802)25:2<88::AID-PPUL3>3.0.CO;2-J

Ratjen, 2001, Effect of inhaled tobramycin on early Pseudomonas aeruginosa colonisation in patients with cystic fibrosis, Lancet, 358, 983, 10.1016/S0140-6736(01)06124-4

Gibson, 2003, Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis, Am J Respir Crit Care Med, 167, 841, 10.1164/rccm.200208-855OC

Gibson, 2007, Duration of treatment effect after tobramycin solution for inhalation in young children with cystic fibrosis, Pediatr Pulmonol, 42, 610, 10.1002/ppul.20625

Taccetti, 2005, Early eradication therapy against Pseudomonas aeruginosa in cystic fibrosis patients, Eur Respir J, 26, 458, 10.1183/09031936.05.00009605

Schelstraete, 2010, Genotype based evaluation of Pseudomonas aeruginosa eradication treatment success in cystic fibrosis patients, J Cyst Fibros, 9, 99, 10.1016/j.jcf.2009.11.006

Munck, 2001, Genotypic characterization of Pseudomonas aeruginosa strains recovered from patients with cystic fibrosis after initial and subsequent colonization, Pediatr Pulmonol, 32, 288, 10.1002/ppul.1121

Griese, 2002, Eradication of initial Pseudomonas aeruginosa colonization in patients with cystic fibrosis, Eur J Med Res, 7, 79

Douglas, 2010, Value of serology in predicting Pseudomonas aeruginosa infection in young children with cystic fibrosis, Thorax, 65, 985, 10.1136/thx.2009.132845

Proesmans, 2012, Comparison of two treatment regimens for eradication of Pseudomonas aeruginosa infection in children with cystic fibrosis, J Cyst Fibros

Treggiari MM, 2011, Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis, Arch Pediatr Adolesc Med, 165, 847, 10.1001/archpediatrics.2011.136

Ratjen, 2010, Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis: the ELITE trial, Thorax, 65, 286, 10.1136/thx.2009.121657

Mayer-Hamblett, 2012, Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis, Pediatr Pulmonol, 47, 125, 10.1002/ppul.21525

Taccetti, 2012, Early antibiotic treatment for Pseudomonas aeruginosa eradication in patients with cystic fibrosis: a randomised multicentre study comparing two different protocols, Thorax, 10.1136/thoraxjnl-2011-200832

Frederiksen, 1997, Antibiotic treatment of initial colonization with Pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis, Pediatr Pulmonol, 23, 330, 10.1002/(SICI)1099-0496(199705)23:5<330::AID-PPUL4>3.0.CO;2-O

Hansen, 2008, Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience, J Cyst Fibros, 7, 523, 10.1016/j.jcf.2008.06.009

McPherson, 2010, Can mucoid Pseudomonas aeruginosa be eradicated in children with cystic fibrosis?, Pediatr Pulmonol, 45, 566, 10.1002/ppul.21220

Troxler, 2012, Clearance of initial mucoid Pseudomonas aeruginosa in patients with cystic fibrosis, Pediatr Pulmonol, 10.1002/ppul.22543