Epidemiology of suicide in bipolar disorders: a systematic review of the literature

Bipolar Disorders - Tập 15 Số 5 - Trang 457-490 - 2013
Maurizio Pompili1, Xénia Gonda2, Gianluca Serafini1, Marco Innamorati1, Leo Sher3, Mario Amore4, Zoltán Rihmer2, Paolo Girardi1,5
1Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy
2Department of Clinical and Theoretical Mental Health, Kútvölgyi Clinical Center, Semmelweis University, Budapest, Hungary
3Mount Sinai School of Medicine and James J. Peters Veterans’ Administration Medical Center New York NY USA
4Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Section of Psychiatry, University of Genova, Genova, Italy
5Villa Rosa Medical Research Center Viterbo Italy

Tóm tắt

ObjectiveSuicidal behavior is a major public health problem worldwide, and its prediction and prevention represent a challenge for everyone, including clinicians. The aim of the present paper is to provide a systematic review of the existing literature on the epidemiology of completed suicides in adult patients with bipolar disorder (BD).MethodsWe performed a Pubmed/Medline, Scopus, PsycLit, PsycInfo, and Cochrane database search to identify all relevant papers published between 1980 and 2011. A total of 34 articles meeting our inclusion criteria were included in the present review.ResultsSeveral prospective follow‐up contributions, many retrospective analyses, and a few psychological autopsy studies and review articles investigated the epidemiology of completed suicides in patients with BD. The main finding of the present review was that the risk for suicide among BD patients was up to 20–30 times greater than that for the general population.ConclusionSpecial attention should be given to the characteristics of suicides in patients with BD. Better insight and understanding of suicide and suicidal risk in this very disabling illness should ultimately help clinicians to adequately detect, and thus prevent, suicidal acts in patients with BD.

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