EphB2 promotes cervical cancer progression by inducing epithelial-mesenchymal transition

Human Pathology - Tập 45 - Trang 372-381 - 2014
Qing Gao1, Wei Liu1, Jiangyi Cai2, Mu Li1, Yane Gao1, Wenjing Lin1, Zongfang Li3,4,5
1Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, PR China
2Department of Pathology, Xi'an Aerospace General Hospital, Shaanxi, Xi'an 710004, PR China
3Department of General Surgery in Cadre's Ward, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, PR China
4National-Local Joint Engineering Research Center of Biodiagnostics & Biotherapy, Xi'an Jiaotong University, Xi'an 710061, PR China
5Key Laboratory of Environment and Genes Related to Diseases of the Education Ministry, School of Medicine, Xi'an Jiaotong University, Shaanxi, Xi'an, PR China

Tài liệu tham khảo

Jemal, 2011, Global cancer statistics, CA Cancer J Clin, 61, 69, 10.3322/caac.20107

Yang, 2008, Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis, Dev Cell, 14, 818, 10.1016/j.devcel.2008.05.009

Gupta, 2006, Cancer metastasis: building a framework, Cell, 127, 679, 10.1016/j.cell.2006.11.001

Polyak, 2009, Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits, Nat Rev Cancer, 9, 265, 10.1038/nrc2620

Nakada, 2011, Role of Eph/ephrin tyrosine kinase in malignant glioma, Neuro Oncol, 13, 1163, 10.1093/neuonc/nor102

Kullander, 2002, Mechanisms and functions of Eph and ephrin signalling, Nat Rev Mol Cell Biol, 3, 475, 10.1038/nrm856

Batlle, 2002, Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB, Cell, 111, 251, 10.1016/S0092-8674(02)01015-2

Nakada, 2005, EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion, Am J Pathol, 167, 565, 10.1016/S0002-9440(10)62998-7

Kumar, 2009, Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression, Cancer Res, 69, 3736, 10.1158/0008-5472.CAN-08-3232

Kosinski, 2007, Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors, Proc Natl Acad Sci U S A, 104, 15418, 10.1073/pnas.0707210104

Pecorelli, 2009, Revised FIGO staging for carcinoma of the cervix, Int J Gynaecol Obstet, 105, 107, 10.1016/j.ijgo.2009.02.009

Liu, 2007, Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors, Cancer Res, 67, 8671, 10.1158/0008-5472.CAN-07-1486

Mani, 2008, The epithelial-mesenchymal transition generates cells with properties of stem cells, Cell, 133, 704, 10.1016/j.cell.2008.03.027

Zou, 1999, An Eph receptor regulates integrin activity through R-Ras, Proc Natl Acad Sci U S A, 96, 13813, 10.1073/pnas.96.24.13813

Nakada, 2004, The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells, Cancer Res, 64, 3179, 10.1158/0008-5472.CAN-03-3667

Narayan, 2007, Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identification of candidate amplified and overexpressed genes, Genes Chromosomes Cancer, 46, 373, 10.1002/gcc.20418

Thiery, 2009, Epithelial-mesenchymal transitions in development and disease, Cell, 139, 871, 10.1016/j.cell.2009.11.007

Acloque, 2009, Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease, J Clin Invest, 119, 1438, 10.1172/JCI38019

Li, 2012, Correlation of TWIST2 up-regulation and epithelial-mesenchymal transition during tumorigenesis and progression of cervical carcinoma, Gynecol Oncol, 124, 112, 10.1016/j.ygyno.2011.09.003

Yan, 2013, Low-dose radiation-induced epithelial-mesenchymal transition through NF-kappaB in cervical cancer cells, Int J Oncol, 42, 1801, 10.3892/ijo.2013.1852

Mayer, 2013, Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix, Br J Cancer, 108, 402, 10.1038/bjc.2012.570

Steinestel, 2013, Overexpression of p16(INK4a) in urothelial carcinoma in situ is a marker for MAPK-mediated epithelial-mesenchymal transition but is not related to human papillomavirus infection, PLoS One, 8, e65189, 10.1371/journal.pone.0065189

Lei, 2012, Up-regulated miR155 reverses the epithelial-mesenchymal transition induced by EGF and increases chemo-sensitivity to cisplatin in human Caski cervical cancer cells, PLoS One, 7, e52310, 10.1371/journal.pone.0052310

Guo, 2012, Slug and Sox9 cooperatively determine the mammary stem cell state, Cell, 148, 1015, 10.1016/j.cell.2012.02.008

Lopez, 2012, Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance, BMC Cancer, 12, 48, 10.1186/1471-2407-12-48

Mulholland, 2012, Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells, Cancer Res, 72, 1878, 10.1158/0008-5472.CAN-11-3132

Wang, 2013, Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype, J Cell Physiol, 228, 556, 10.1002/jcp.24162

Wong, 2013, Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression, Genes Dev, 27, 670, 10.1101/gad.210427.112

Santibanez, 2010, The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras, Carcinogenesis, 31, 2145, 10.1093/carcin/bgq199

Thông tin
Thông tin xuất bản

Human Pathology

Tập 45

372-381

Thông tin tác giả