Low-dose radiation-induced epithelial-mesenchymal transition through NF-κB in cervical cancer cells

International Journal of Oncology - Tập 42 Số 5 - Trang 1801-1806 - 2013
Yan Shi1, Yu Wang2, Qifeng Yang3, Xiaoyan Li3, Xiaoli Kong3, Ning Zhang3, Cunzhong Yuan2, Ning Yang2, Beihua Kong2
1Department of Obstetrics and Gynaecology, Qilu Hospital of Shandong University, Jinan, Shandong, PR China.
2Department of Obstetrics and Gynaecology, QiLu Hospital of Shandong University, Jinan, Shandong, P.R. China
3Department of Breast Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China

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Tài liệu tham khảo

Lee, 2012, Epithelial-mesenchymal transition in cervical carcinoma, Am J Transl Res, 4, 1

Siegel, 2012, Cancer statistics, 2012, CA Cancer J Clin, 62, 10, 10.3322/caac.20138

Kitahara, 2002, Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis, Neoplasia, 4, 295, 10.1038/sj.neo.7900251

Andarawewa, 2007, Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition, Cancer Res, 67, 8662, 10.1158/0008-5472.CAN-07-1294

Qing, 2010, Microarray analysis of DNA damage repair gene expression profiles in cervical cancer cells radioresistant to 252Cf neutron and X-rays, BMC Cancer, 10, 71, 10.1186/1471-2407-10-71

Liu, 2004, p73 expression is associated with the cellular radiosensitivity in cervical cancer after radiotherapy, Clin Cancer Res, 10, 3309, 10.1158/1078-0432.CCR-03-0119

Barcellos-Hoff, 1993, Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland, Cancer Res, 53, 3880

Ewan, 2002, Transforming growth factor-beta1 mediates cellular response to DNA damage in situ, Cancer Res, 62, 5627

Thiery, 2009, Epithelial-mesenchymal transitions in development and disease, Cell, 139, 871, 10.1016/j.cell.2009.11.007

Zeisberg, 2009, Biomarkers for epithelial-mesenchymal transitions, J Clin Invest, 119, 1429, 10.1172/JCI36183

Thiery, 2002, Epithelial-mesenchymal transitions in tumour progression, Nat Rev Cancer, 2, 442, 10.1038/nrc822

Moody, 2005, The transcriptional repressor Snail promotes mammary tumor recurrence, Cancer Cell, 8, 197, 10.1016/j.ccr.2005.07.009

Lee, 2008, Epithelialmesenchymal transition in cervical cancer: correlation with tumor progression, epidermal growth factor receptor overexpression and snail up-regulation, Clin Cancer Res, 14, 4743, 10.1158/1078-0432.CCR-08-0234

Hsu, 2010, Regulation of excision repair cross-complementation group 1 by Snail contributes to cisplatin resistance in head and neck cancer, Clin Cancer Res, 16, 4561, 10.1158/1078-0432.CCR-10-0593

Yang, 2006, Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines, Clin Cancer Res, 12, 4147, 10.1158/1078-0432.CCR-06-0038

Cheng, 2007, Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion and resistance to paclitaxel, Cancer Res, 67, 1979, 10.1158/0008-5472.CAN-06-1479

Arumugam, 2009, Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer, Cancer Res, 69, 5820, 10.1158/0008-5472.CAN-08-2819

Li, 2001, Effector genes altered in MCF-7 human breast cancer cells after exposure to fractionated ionizing radiation, Radiat Res, 155, 543, 10.1667/0033-7587(2001)155[0543:EGAIMH]2.0.CO;2

Min, 2008, NF-kappaB and epithelial to mesenchymal transition of cancer, J Cell Biochem, 104, 733, 10.1002/jcb.21695

Cho, 2010, Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells, Cancer Lett, 293, 230, 10.1016/j.canlet.2010.01.013

Li, 2011, Metadherin enhances the invasiveness of breast cancer cells by inducing epithelial to mesenchymal transition, Cancer Sci, 102, 1151, 10.1111/j.1349-7006.2011.01919.x

Thiery, 2003, Epithelial-mesenchymal transitions in development and pathologies, Curr Opin Cell Biol, 15, 740, 10.1016/j.ceb.2003.10.006

Schmalhofer, 2009, E-cadherin, beta-catenin and ZEB1 in malignant progression of cancer, Cancer Metastasis Rev, 28, 151, 10.1007/s10555-008-9179-y

Hsu, 2007, KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition, Cancer Res, 67, 11064, 10.1158/0008-5472.CAN-07-2443

Huber, 2004, NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression, J Clin Invest, 114, 569, 10.1172/JCI200421358

Strippoli, 2010, p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition, J Cell Sci, 123, 4321, 10.1242/jcs.071647

Li, 2012, Epithelial-mesenchymal transition induced by TNF-alpha requires NF-kappaB-mediated transcriptional upregulation of Twist1, Cancer Res, 72, 1290, 10.1158/0008-5472.CAN-11-3123