The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
Sendurai A. Mani1,2, Wenjun Guo1, Mai-Jing Liao1, Elinor Ng. Eaton1, Ayyakkannu Ayyanan3, Alicia Y. Zhou1,4, Mary Brooks1, Ferenc Reinhard1, Cheng Cheng Zhang1, Michail Shipitsin5,6, Lauren L. Campbell5,7, Kornelia Polyak5,8,7, Cathrin Brisken3, Jing Yang9, Robert A. Weinberg1,10
1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142 USA
2Department of Molecular Pathology, University of Texas M.D. Anderson Cancer Center, 7435 Fannin Street, Houston, TX 77054, USA
3Ecole polytechnique fédérale de Lausanne (EPFL), ISREC - Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, CH-1066 Epalinges, Switzerland
4Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115 USA
6Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
7Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA
8Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA
9Department of Pharmacology and Pediatrics, University of California, San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0636, USA
10Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA