Eosinophilia inAscaris suum-reinfected mice

Journal of Helminthology - Tập 62 Số 1 - Trang 51-57 - 1988
Kazuo Sugane1
1Department of Parasitology, Faculty of Medicine, Shinshu University, Nagano Prefecture, Japan.

Tóm tắt

ABSTRACT

The secondary response of eosinophilia has been studied in mice infected withA. suum. In mice infected orally with 1000A. suumeggs, larvae disappeared from the body within two weeks after infection. The number of peripheral blood eosinophils decreased to the pre-infection level within eight weeks. A typical secondary response of IgG antibody production to egg antigen was found after reinfection with 1000 eggs. The number of peripheral blood eosinophils increased more rapidly after reinfection than after the primary infection. However, the peak number of eosinophils after reinfection was similar to that after primary infection, and the long-lasting characteristics of eosinophilia after reinfection did not differ from those after primary infection. These results suggest that the secondary response of eosinophilia is characterized by a rapid increase in the number of eosinophils inA. suum-reinfected mice.

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Tài liệu tham khảo

10.1084/jem.131.6.1288

Cline, 1979, Controlling the production of blood cells, Blood, 53, 157, 10.1182/blood.V53.1.157.157

10.4269/ajtmh.1974.23.378

10.1016/0014-4894(76)90109-0

Bartelmez, 1980, Differential regulation of spleen cell-mediated eosinophil and neutrophil-macrophage production, Blood, 55, 489, 10.1182/blood.V55.3.489.489

10.1111/j.1365-3024.1982.tb00442.x

10.2307/3275079

10.2307/3281612

10.1002/jcp.1040840214

Bartelmez, 1980, Stimulation of eosinophil production in vitro by eosinophilopoietin and spleen cell-derived eosinophil growth-stimulating factor, Blood, 56, 706, 10.1182/blood.V56.4.706.706

Sugane, 1983, Purification and characterization of excretory and secretory antigen of Toxocara canis larvae, Immunology, 50, 113

10.4269/ajtmh.1980.29.799

10.4269/ajtmh.1979.28.237

Ackerman, 1981, Eosinophilia and elevated serum levels of eosinophil major basic protein and Charcot-Leyden crystal protein (lysophospholipase) after treatment of patients with Bancroft's filariasis, Journal of Immunology, 127, 1093, 10.4049/jimmunol.127.3.1093

10.2307/3278951

10.1016/S0140-6736(46)91306-2

Oshima, 1976, Observations of the age resistance, eosinophilia and larval behavior in helminth-free beagles infected with Toxocara canis, Japanese Journal of Parasitology, 25, 447

10.1093/infdis/90.2.165

Thông tin
Thông tin xuất bản

Journal of Helminthology

Tập 62 Số 1

51-57

Thông tin tác giả