Enhancing trabecular outflow by disrupting the actin cytoskeleton, increasing uveoscleral outflow with prostaglandins, and understanding the pathophysiology of presbyopia

Experimental Eye Research - Tập 86 - Trang 3-17 - 2008
Paul L. Kaufman1
1University of Wisconsin, School of Medicine and Public Health, Ophthalmology & Visual Sciences, 2870 University Ave, Suite #102, Madison, WI 53705, USA

Tài liệu tham khảo

Bárány, 1962, The mode of action of pilocarpine on outflow resistance in the eye of a primate (Cercopithecus ethiops), Invest. Ophthalmol, 1, 712 Bárány, 1966, The mode of action of miotics on outflow resistance. A study of pilocarpine in the vervet monkey (Cercopithecus ethiops), Trans. Ophthalmol. Soc. UK, 86, 539 Bárány, 1967, The immediate effect on outflow resistance of intravenous pilocarpine in the vervet monkey, Invest. Ophthalmol, 6, 373 Bárány, 1968, Topical epinephrine effects on true outflow resistance and pseudofacility in vervet monkeys studied by a new anterior chamber perfusion technique, Invest. Ophthalmol, 7, 88 Bárány, 1965, Localized contraction and relaxation within the ciliary muscle of the vervet monkey (Cercopithecus ethiops), 287 Bill, 1967, Effects of atropine and pilocarpine on aqueous humour dynamics in cynomolgus monkeys (Macaca irus), Exp. Eye Res., 6, 120, 10.1016/S0014-4835(67)80062-9 Bill, 1969, Early effects of epinephrine on aqueous humor dynamics in vervet monkeys (Cercopithecus ethiops), Exp. Eye Res., 8, 35, 10.1016/S0014-4835(69)80078-3 Bito, 1989, A physiological approach to glaucoma management: the use of local hormones and the pharmacokinetics of prostaglandin esters, Vol. 312, 329 Bito, 2001, A new approach to the medical management of glaucoma, from the bench to the clinic, and beyond (Proctor Lecture), Invest. Ophthalmol. Vis. Sci., 42, 1126 Bito, 1987, Presbyopia: the need for a closer look, 411 Bito, 1982, Age-dependent loss of accommodative amplitude in rhesus monkeys: an animal model for presbyopia, Invest. Ophthalmol. Vis. Sci., 23, 23 Borrás, 2001, Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo, J. Gene Med, 3, 437, 10.1002/jgm.210 Brown, 1981, Mechanism of action of cytochalasin: evidence that it binds to actin filament ends, J. Cell Biol., 88, 487, 10.1083/jcb.88.3.487 Burridge, 2004, Rho and Rac take center stage, Cell, 116, 167, 10.1016/S0092-8674(04)00003-0 Camras, 1977, Reduction of intraocular pressure by prostaglandins applied topically to the eyes of conscious rabbits, Invest. Ophthalmol. Vis. Sci., 16, 1125 Citi, 1994, Cytoskeletal involvement in the modulation of cell–cell junctions by the protein kinase inhibitor H-7, J. Cell Sci., 107, 683, 10.1242/jcs.107.3.683 Crawford, 1987, Pilocarpine antagonizes PGF2α-induced ocular hypotension: Evidence for enhancement of uveoscleral outflow by PGF2α, Arch. Ophthalmol, 105, 1112, 10.1001/archopht.1987.01060080114039 Crawford, 1987, Effects of topical PGF2α on aqueous humor dynamics in cynomolgus monkeys, Curr. Eye Res., 6, 1035, 10.3109/02713688709034874 Crawford, 1989, Reproducible stimulation of ciliary muscle contraction in the cynomolgus monkey via a permanent indwelling midbrain electrode, Brain Res., 503, 265, 10.1016/0006-8993(89)91673-9 Croft, 1996, Aging effects on accommodation and outflow facility responses to pilocarpine in humans, Arch. Ophthalmol, 114, 586, 10.1001/archopht.1996.01100130578015 Croft, 1998, Accommodation dynamics in aging rhesus monkeys, Am. J. Physiol, 275, R1885 Croft, 2006, Accommodative ciliary body and lens function in rhesus monkeys. 1. Normal lens, zonule and ciliary process configuration in the iridectomized eye, Invest. Ophthalmol. Vis. Sci., 47, 1076, 10.1167/iovs.04-1523 Croft, 2006, The zonula, lens and circumlental space in the normal iridectomized rhesus monkey eye, Invest. Ophthalmol. Vis. Sci., 47, 1087, 10.1167/iovs.04-1524 Duane, 1922, Studies in monocular and binocular accommodation with their clinical applications, Am. J. Ophthalmol, 5, 867, 10.1016/S0002-9394(22)90793-7 Epstein, 1999, Acto-myosin drug effects and aqueous outflow function, Invest. Ophthalmol. Vis. Sci., 40, 74 Gabelt, 1989, Prostaglandin F2a increases uveoscleral outflow in the cynomolgus monkey, Exp. Eye Res., 49, 389, 10.1016/0014-4835(89)90049-3 Gabelt, 1990, Ciliary muscle muscarinic binding sites, choline acetyltransferase and acetylcholinesterase in aging rhesus monkeys, Invest. Ophthalmol. Vis. Sci., 31, 2431 Gabelt, 1991, Outflow facility and its response to pilocarpine decline in aging rhesus monkeys, Arch. Ophthalmol, 109, 879, 10.1001/archopht.1991.01080060143044 Gabelt, 2006, Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments, Exp. Eye Res., 82, 935, 10.1016/j.exer.2005.12.002 Gaton, 2001, Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway following topical prostaglandin F(2 alpha)-isopropyl ester treatment, Arch. Ophthalmol, 119, 1165, 10.1001/archopht.119.8.1165 Geiger, 2002, Exploring the neighborhood: adhesion-coupled cell mechanosensors, Cell, 110, 139, 10.1016/S0092-8674(02)00831-0 Geiger, 2001, Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk, Nat. Rev. Mol. Cell. Biol., 2, 793, 10.1038/35099066 Grosheva, 2006, Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells, Exp. Eye Res., 82, 945, 10.1016/j.exer.2006.01.006 Helfman, 1999, Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions, Mol. Biol. Cell, 10, 3097, 10.1091/mbc.10.10.3097 Hu, 2006, Monkey organ-cultured anterior segments; technique and response to H-7, Exp. Eye Res., 82, 1100, 10.1016/j.exer.2005.12.004 Johnson, 1992, Modulation of outflow resistance by the pores of the inner wall endothelium, Invest. Ophthalmol. Vis. Sci., 33, 1670 Kaufman, 1979, Aqueous humor dynamics following total iridectomy in the cynomolgus monkey, Invest. Ophthalmol. Vis. Sci., 18, 870 Kaufman, 1986, Effects of Intracamerally Infused prostaglandins on outflow facility in cynomolgus monkey eyes with intact or retrodisplaced ciliary muscle, Exp. Eye Res., 43, 819, 10.1016/S0014-4835(86)80012-4 Kaufman, 1976, Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey, Invest. Ophthalmol, 15, 793 Kaufman, 1977, Recent observation concerning the effect of cholinergic drugs on outflow facility in monkeys, 415 Kaufman, 1977, Cytochalasin B reversibly increases outflow facility in the eye of the cynomolgus monkey, Invest. Ophthalmol. Vis. Sci., 16, 47 Kaufman, 1981, Adrenergic drug effects on aqueous outflow facility following ciliary muscle retrodisplacement in the cynomolgus monkey, Invest. Ophthalmol. Vis. Sci., 20, 644 Kaufman, 1982, The occurrence of senile cataracts, ocular hypertension and glaucoma in rhesus monkeys, Exp. Eye Res., 34, 287, 10.1016/0014-4835(82)90061-6 Kaufman, 1993, Aging, accommodation and outflow facility, 257 Kaufman, 1975, Total iridectomy in the primate in vivo: surgical technique and postoperative anatomy, Invest. Ophthalmol, 14, 766 Kaufman, 1981, Effect of total iridectomy on outflow facility responses to adrenergic drugs in cynomolgus monkeys, Exp. Eye Res., 33, 65, 10.1016/S0014-4835(81)80082-6 Kaufman, 1977, Effect of cytochalasin B on conventional drainage of aqueous humor in the cynomolgus monkey, Exp. Eye Res, 25, 411, 10.1016/S0014-4835(77)80037-7 Kiland, 2006, Effect of H-7 and Lat-B on retinal physiology, Curr. Eye Res., 31, 441, 10.1080/02713680600672185 Lindsey, 1996, Prostaglandins increase proMMP-1 and proMMP-3 secretion by human ciliary smooth muscle cells, Curr. Eye Res., 15, 869, 10.3109/02713689609017628 Lindsey, 1997, Prostaglandins alter extracellular matrix adjacent to human ciliary muscle cells in vitro, Invest. Ophthalmol. Vis. Sci., 38, 2214 Liu, 2005, The effects of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes, Mol. Vis, 11, 1112 Liu, 2007, Glaucoma gene therapy, Expert Rev. Ophthalmol, 2, 227, 10.1586/17469899.2.2.227 Low, 1975, Stabilization of F-actin by phalloidin. Reversal of the destabilizing effect of cytochalasin B, FEBS Lett., 54, 263, 10.1016/0014-5793(75)80088-3 Lütjen-Drecoll, 1977, Light and electron microscopy of the anterior chamber angle structures following surgical disinsertion of the ciliary muscle in the cynomolgus monkey, Invest. Ophthalmol. Vis. Sci., 16, 218 Lütjen-Drecoll, 1988, Age changes in rhesus monkey ciliary muscle: light and electron microscopy, Exp. Eye Res., 47, 885, 10.1016/0014-4835(88)90070-X Lütjen-Drecoll, 1988, Age-related loss of morphologic responses to pilocarpine in rhesus monkey ciliary muscle, Arch. Ophthalmol, 106, 1591, 10.1001/archopht.1988.01060140759051 Miranda, 1986, Ocular development and aging. 2. Different basic patterns of lenticular growth in cats and rhesus monkeys (RhMs) and the lack of discernible effect of sunlight on lenticular aging in RhMs, Invest. Ophthalmol. Vis. Sci., 27 Neider, 1990, In vivo videography of the rhesus monkey accommodative apparatus. Age-related loss of ciliary muscle response to central stimulation, Arch. Ophthalmol, 108, 69, 10.1001/archopht.1990.01070030075032 Neufeld, 1982, Receptor mechanisms for epinephrine and timolol, 113 Neufeld, 1975, Adenosine 3′,5′-monophosphate analogue increases the outflow facility of the primate eye, Invest. Ophthalmol, 14, 688 Neufeld, 1972, Cyclic-AMP in the aqueous humor: the effects of adrenergic agonists, Exp. Eye Res., 14, 242, 10.1016/0014-4835(72)90009-7 Neufeld, 1973, Cyclic-AMP in the aqueous humor: the effects of repeated topical epinephrine administration and sympathetic denervation, Exp. Eye Res., 16, 265, 10.1016/0014-4835(73)90092-4 Nilsson, 1989, Increased uveoscleral outflow as a possible mechanism of ocular hypotension caused by prostaglandin F2a-1-isopropylester in the cynomolgus monkey, Exp. Eye Res., 48, 707, 10.1016/0014-4835(89)90011-0 Okka, 2004, Effect of low-dose latrunculin B on anterior segment physiologic features in the monkey eye, Arch. Ophthalmol, 122, 1482, 10.1001/archopht.122.10.1482 Overby, 2002, The mechanism of increasing outflow facility during washout in the bovine eye, Invest. Ophthalmol. Vis. Sci., 42, 3455 Perkins, 1988, Trabecular meshwork cells grown on filters: conductivity and cytochalasin effects, Invest. Ophthalmol. Vis. Sci., 29, 1836 Peterson, 1999, Latrunculin-A increases outflow facility in the monkey, Invest. Ophthalmol. Vis. Sci., 40, 931 Peterson, 2000, Effect of latrunculin-B on outflow facility in monkeys, Exp. Eye Res., 70, 307, 10.1006/exer.1999.0797 Peterson, 2000, Latrunculin's effects on intraocular pressure, aqueous humor flow and corneal endothelium, Invest. Ophthalmol. Vis. Sci., 41, 1749 Poeschla, 2006, Transduction of non-human primate trabecular meshwork with lentiviral vectors, Invest. Ophthalmol. Vis. Sci., 47 Polansky, 1979, Human trabecular cells: I. Establishment in tissue culture and growth characteristics, Invest. Ophthalmol. Vis. Sci., 18, 1043 Poyer, 1993, Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists, Curr. Eye Res., 12, 413, 10.3109/02713689309024623 Rao, 2001, Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632, Invest. Ophthalmol. Vis. Sci., 42, 1029 Robinson, 1991, Cytochalasin B potentiates epinephrine's outflow facility increasing effect, Invest. Ophthalmol. Vis. Sci., 32, 1614 Robinson, 1994, Phalloidin inhibits epinephrine's and cytochalsin B's facilitation of aqueous outflow, Arch. Ophthalmol, 112, 1610, 10.1001/archopht.1994.01090240116035 Rohen, 1967, The relation between the ciliary muscle and the trabecular meshwork and its importance for the effect of miotics on aqueous outflow resistance, Albrecht von Graefes Arch. Klin. Exp. Ophthalmol., 172, 23, 10.1007/BF00577152 Rohen, 1981, The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sections, Invest. Ophthalmol. Vis. Sci., 21, 574 Ryder, 1988, The cytoskeleton of the cultured human trabecular cell. Characterization and drug responses, Invest. Ophthalmol. Vis. Sci., 29, 251 Sabanay, 2000, H-7 effects on structure and fluid conductance of monkey trabecular meshwork, Arch. Ophthalmol, 118, 955 Sabanay, 2004, Functional and structural reversibility of H-7 effects on the conventional aqueous outflow pathway in monkeys, Exp. Eye Res., 78, 137, 10.1016/j.exer.2003.09.007 Sabanay, 2006, Latrunculin B effects on trabecular meshwork and corneal endothelial morphology in monkeys, Exp. Eye Res., 82, 236, 10.1016/j.exer.2005.06.017 Sagara, 1999, Topical prostaglandin F2a treatment reduces collagen types I, III, and IV in the monkey uveoscleral outflow pathway, Arch. Ophthalmol, 117, 794, 10.1001/archopht.117.6.794 Sears, 1966, The mechanism of action of adrenergic drugs in glaucoma, Invest. Ophthalmol, 5, 115 Sears, 1975, Adrenergic modulation of the outflow of aqueous humor, Invest. Ophthalmol, 14, 83 Stjernschantz, 2001, From PGF2α-isopropyl ester to latanoprost: a review of the development of Xalatan. The Proctor Lecture, Invest. Ophthalmol. Vis. Sci., 42, 1134 Svedbergh, 1978, Cytochalasin B-induced structural changes in the anterior ocular segment of the cynomolgus monkey, Invest. Ophthalmol. Vis. Sci., 17, 718 Tamm, 1990, Age-related changes of the ciliary muscle in comparison with changes induced by treatment with prostaglandin F2a. An ultrastructural study in rhesus and cynomolgus monkeys, Mech. Ageing Dev., 51, 101, 10.1016/0047-6374(90)90093-U Tamm, 1992, Age-related loss of ciliary muscle mobility in the rhesus monkey: role of the choroid, Arch. Ophthalmol, 110, 871, 10.1001/archopht.1992.01080180143043 Tian, 1998, H-7 disrupts the actin cytoskeleton and increases outflow facility, Arch. Opthalmol, 116, 633, 10.1001/archopht.116.5.633 Tian, 2000, Cytoskeletal involvement in the regulation of aqueous humor outflow, Invest. Ophthalmol. Vis. Sci., 41, 619 Tian, 2004, Effects of topical H-7 on outflow facility, intraocular pressure and corneal thickness in monkeys, Arch. Ophthalmol, 122, 1171, 10.1001/archopht.122.8.1171 Weinreb, 1986, The cytoskeleton of the cynomolgus monkey trabecular cell II. Influence of cytoskeleton-active drugs, Invest. Ophthalmol. Vis. Sci., 27, 1312 Weinreb, 2002, Effects of prostaglandins on the aqueous humor pathways, Surv. Ophthalmol, 47, S53, 10.1016/S0039-6257(02)00306-5