Enhanced absorption of boswellic acids by a micellar solubilized delivery form of Boswellia extract

NFS Journal - Tập 11 - Trang 12-16 - 2018
Jürgen Meins1, Dariush Behnam2, Mona Abdel-Tawab1
1Zentrallaboratorium Deutscher Apotheker, Carl-Mannich-Str. 20, Eschborn 65760, Germany
2AQUANOVA AG, Birkenweg 8-10, Darmstadt 64295, Germany

Tài liệu tham khảo

Smith, 2016, Sales of herbal dietary supplements in US increased 7.5% in 2015, HerbalGram, 111, 67 Abdel-Tawab, 2011, Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data, Clin. Pharmacokinet., 50, 349, 10.2165/11586800-000000000-00000 Ammon, 2016, Boswellic acids and their role in chronic inflammatory diseases, Adv. Exp. Med. Biol., 928, 291, 10.1007/978-3-319-41334-1_13 Krüger, 2009, Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2, Eur. J. Pharm. Sci., 36, 275, 10.1016/j.ejps.2008.10.005 Gerbeth, 2013, In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins, Fitoterapia, 84, 99, 10.1016/j.fitote.2012.10.009 Frank, 2017, Transepithelial tansport of curcumin in Caco-2 cells is significantly enhanced by micellar solubilisation, Plant Foods Hum. Nutr., 72, 48, 10.1007/s11130-016-0587-9 Schiborr, 2014, The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes, Mol. Nutr. Food Res., 58, 516, 10.1002/mnfr.201300724 Buechele, 2003, Analysis of 12 different pentacyclic triterpenic acids from frankincense in human plasma by high-performance liquid chromatography and photodiode array detection, J. Chromatogr. B, 795, 355, 10.1016/S1570-0232(03)00555-5 Reising, 2005, Determination of boswellic acids in brain and plasma by high-performance liquid chromatography/tandem mass spectrometry, Anal. Chem., 77, 6640, 10.1021/ac0506478 Gerbeth, 2011, Determination of major boswellic acids in plasma by high pressure liquid chromatography/mass spectrometry, J. Pharm. Biomed. Anal., 56, 998, 10.1016/j.jpba.2011.07.026 Hüsch, 2013, Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome®) of Boswellia extract, Fitoterapia, 84, 89, 10.1016/j.fitote.2012.10.002