Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis

Menu, 2011, Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome, Cell Death Dis., 2, e137, 10.1038/cddis.2011.18

Abais, 2013, NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia, Antioxid. Redox Signal., 18, 1537, 10.1089/ars.2012.4666

Zhang, 2012, Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia, Hypertension, 60, 154, 10.1161/HYPERTENSIONAHA.111.189688

Martinon, 2002, The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta, Mol. Cell, 10, 417, 10.1016/S1097-2765(02)00599-3

Lamkanfi, 2009, Fungal zymosan and mannan activate the cryopyrin inflammasome, J. Biol. Chem., 284, 20574, 10.1074/jbc.M109.023689

Kanneganti, 2006, Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA, J. Biol. Chem., 281, 36560, 10.1074/jbc.M607594200

Kepp, 2010, Pyroptosis — a cell death modality of its kind?, Eur. J. Immunol., 40, 627, 10.1002/eji.200940160

Lamkanfi, 2011, Emerging inflammasome effector mechanisms, Nat. Rev. Immunol., 11, 213, 10.1038/nri2936

Nicolson, 2014, Lipid replacement therapy: a natural medicine approach to replacing damaged lipids in cellular membranes and organelles and restoring function, Biochim. Biophys. Acta, 1838, 1657, 10.1016/j.bbamem.2013.11.010

Misawa, 2013, Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome, Nat. Immunol., 14, 454, 10.1038/ni.2550

Gattorno, 2013, Beyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescence, Arthritis Rheum., 65, 1137, 10.1002/art.37882

Scuccimarri, 2012, Kawasaki disease, Pediatr. Clin. North Am., 59, 425, 10.1016/j.pcl.2012.03.009

Lee, 2012, Interleukin-1beta is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease, Circulation, 125, 1542, 10.1161/CIRCULATIONAHA.111.072769

Lehman, 1985, Coronary arteritis in mice following the systemic injection of group B Lactobacillus casei cell walls in aqueous suspension, Arthritis Rheum., 28, 652, 10.1002/art.1780280609

Xia, 2014, Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin, Am. J. Pathol., 184, 1617, 10.1016/j.ajpath.2014.01.032

Xia, 2011, Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin, Cardiovasc. Res., 89, 401, 10.1093/cvr/cvq286

Zhang, 2001, Production and metabolism of ceramide in normal and ischemic-reperfused myocardium of rats, Basic Res. Cardiol., 96, 267, 10.1007/s003950170057

Mayet, 1996, Antibodies to proteinase 3 mediate expression of vascular cell adhesion molecule-1 (VCAM-1), Clin. Exp. Immunol., 103, 259, 10.1046/j.1365-2249.1996.d01-626.x

Xiao, 2013, Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility, Circulation, 128, 632, 10.1161/CIRCULATIONAHA.113.002714

Bryan, 2009, Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain, J. Immunol., 182, 3173, 10.4049/jimmunol.0802367

Bryan, 2010, Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes, J. Inflamm., 7, 23, 10.1186/1476-9255-7-23

Nuki, 2008, Colchicine: its mechanism of action and efficacy in crystal-induced inflammation, Curr. Rheumatol. Rep., 10, 218, 10.1007/s11926-008-0036-3

Kirkegaard, 2010, Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology, Nature, 463, 549, 10.1038/nature08710

Granato, 2013, HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma, Cell Death Dis., 4, e730, 10.1038/cddis.2013.263

Martinon, 2006, Gout-associated uric acid crystals activate the NALP3 inflammasome, Nature, 440, 237, 10.1038/nature04516

Hornung, 2008, Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization, Nat. Immunol., 9, 847, 10.1038/ni.1631

Hoegen, 2011, The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release, J. Immunol., 187, 5440, 10.4049/jimmunol.1100790

Chen, 2012, Marked acceleration of atherosclerosis after Lactobacillus casei-induced coronary arteritis in a mouse model of Kawasaki disease, Arterioscler. Thromb. Vasc. Biol., 32, e60, 10.1161/ATVBAHA.112.249417

Nakatani, 2003, Circulating endothelial cells in Kawasaki disease, Clin. Exp. Immunol., 131, 536, 10.1046/j.1365-2249.2003.02091.x

Fukazawa, 2007, Coronary artery aneurysm induced by Kawasaki disease in children show features typical senescence, Circ. J., 71, 709, 10.1253/circj.71.709

Yu, 2004, Enhanced iNOS expression in leukocytes and circulating endothelial cells is associated with the progression of coronary artery lesions in acute Kawasaki disease, Pediatr. Res., 55, 688, 10.1203/01.PDR.0000113464.93042.A4

Takahashi, 2005, Neutrophilic involvement in the damage to coronary arteries in acute stage of Kawasaki disease, Pediatr. Int., 47, 305, 10.1111/j.1442-200x.2005.02049.x

Kaufmann, 2007, Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1, Circulation, 116, 276, 10.1161/CIRCULATIONAHA.106.684738

Kaufmann, 2010, Molecular imaging of the initial inflammatory response in atherosclerosis: implications for early detection of disease, Arterioscler. Thromb. Vasc. Biol., 30, 54, 10.1161/ATVBAHA.109.196386

Xiang, 2011, Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells, J. Immunol., 187, 4809, 10.4049/jimmunol.1102093

Mohamed, 2014, Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet, Diabetologia, 57, 413, 10.1007/s00125-013-3101-z

Zhou, 2011, A role for mitochondria in NLRP3 inflammasome activation, Nature, 469, 221, 10.1038/nature09663

Mariathasan, 2006, Cryopyrin activates the inflammasome in response to toxins and ATP, Nature, 440, 228, 10.1038/nature04515

Jin, 2010, Molecular mechanism of NLRP3 inflammasome activation, J. Clin. Immunol., 30, 628, 10.1007/s10875-010-9440-3

Duewell, 2010, NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals, Nature, 464, 1357, 10.1038/nature08938

Goncalves, 2013, NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production, PLoS Negl. Trop. Dis., 7, e2469, 10.1371/journal.pntd.0002469

Li, 2009, Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells, Am. J. Pathol., 175, 1124, 10.2353/ajpath.2009.090113

Huck, 2012, Porphyromonas gingivalis and its lipopolysaccharide differentially regulate the expression of cathepsin B in endothelial cells, Mol. Oral Microbiol., 27, 137, 10.1111/j.2041-1014.2012.00638.x

Duong, 2003, Superantigenic activity is responsible for induction of coronary arteritis in mice: an animal model of Kawasaki disease, Int. Immunol., 15, 79, 10.1093/intimm/dxg007

Lin, 2012, Augmented TLR2 expression on monocytes in both human Kawasaki disease and a mouse model of coronary arteritis, PLoS ONE, 7, e38635, 10.1371/journal.pone.0038635