Efficacy of donkey's milk in treating highly problematic cow's milk allergic children: An in vivo and in vitro study

Pediatric Allergy and Immunology - Tập 18 Số 3 - Trang 258-264 - 2007
Giovanna Monti1, Enrico Bertino2, Maria Cristina Muratore1, Alessandra Coscia2, Francesco Cresi1, L Silvestro1, C Fabris2, Donatella Fortunato3, Maria Gabriella Giuffrida3, Amedeo Conti3
1Department of Paediatric and Adolescence Science, Regina Margherita Children's Hospital, Turin, Italy
2Neonatal Unit, Department of Paediatric and Adolescence Science, University of Turin, Italy
3CNR-Institute of Science of Food Production, Turin, Italy

Tóm tắt

Successful therapy in cow's milk protein allergy rests on completely eliminating cow's milk proteins from the child's diet: it is thus necessary to provide a replacement food. This prospective study investigated tolerance of donkey's milk in a population of 46 selected children with cow's milk protein allergy, for whom it was not possible to use any cow's milk substitute. Thirty‐eight children (82.6%) liked and tolerated donkey's milk at the challenge and for the entire duration of follow‐up. Catch‐up growth was observed in all subjects with growth deficit during cow's milk proteins challenge. The degree of cross‐reactivity of immunoglobulin E (IgE) with donkey's milk proteins was very weak and aspecific. Donkey's milk was found to be a valid alternative to both IgE‐mediated and non‐IgE‐mediated cow's milk proteins allergy, including in terms of palatability and weight‐height gain.

Từ khóa


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Thông tin
Thông tin xuất bản

Pediatric Allergy and Immunology

Tập 18 Số 3

258-264

Thông tin tác giả