Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress☆1☆Contents reflect the views of the authors and do not represent any official view(s) of NIEHS, EPA, or DOD.1Abbreviations: PCBs, polychlorinated biphenyls; GST, glutathione transferase; GPX, glutathione peroxidase; SeGPX, selenium-dependent glutathione peroxidase; GR, glutathione reductase; MOPS, 3-{N-morpholino}propane sulfonic acid buffer; CDNB, 1-chloro-2,4-dinitrobenzene; PB, phenobarbital; 3-MC, 3-methylcholanthrene; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; AhR, aryl hydrocarbon receptor; XRE, xenobiotic response element; ROS, reactive oxygen species; and GSPx1, cytosolic selenium-dependent glutathione peroxidase gene.

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