Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells

Journal of Laboratory and Clinical Medicine - Tập 145 - Trang 98-104 - 2005
Xiaodong Zhang1, Nan Dong1, Hang Zhang1, Jiacong You2, Honghui Wang2, Lihong Ye2
1Department of Cancer Research, Institute for Molecular Biology, Nankai University, Tianjin, People’s Republic of China
2Department of Biochemistry, College of Life Sciences, Nankai University, Tianjin, People’s Republic of China.

Tài liệu tham khảo

Chen, 1993, The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks, J Virol, 67, 1218, 10.1128/JVI.67.3.1218-1226.1993

Zoulim, 1994, Woodchuck hepatitis virus X protein is required for viral infection in vivo, J Virol, 68, 2026, 10.1128/JVI.68.3.2026-2030.1994

Benn, 1994, Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade, Proc Natl Acad Sci U S A, 91, 10350, 10.1073/pnas.91.22.10350

Lucito, 1992, Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C, J Virol, 66, 983, 10.1128/JVI.66.2.983-991.1992

Luber, 1991, Multiple simian virus 40 enhancer elements mediate the trans-activating function of the X protein of hepatitis B virus, Virology, 184, 808, 10.1016/0042-6822(91)90458-N

Mahe, 1991, Hepatitis B virus X protein transactivates human interleukin-8 gene through acting on nuclear factor kB and CCAAT/enhancer-binding protein-like cis-elements, J Biol Chem, 266, 13759, 10.1016/S0021-9258(18)92765-1

Seto, 1991, Trans-activation of the human immunodeficiency virus long terminal repeat by the hepatitis B virus X protein, Proc Natl Acad Sci U S A, 85, 8286, 10.1073/pnas.85.21.8286

Seto, 1990, Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors, Nature, 344, 72, 10.1038/344072a0

Su, 1996, Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins, J Virol, 70, 4558, 10.1128/JVI.70.7.4558-4566.1996

Twu, 1989, Hepatitis B virus X gene activates kappa B-like enhancer sequences in the long terminal repeat of human immunodeficiency virus, Proc Natl Acad Sci U S A, 86, 5168, 10.1073/pnas.86.13.5168

Aufiero, 1990, The hepatitis B virus X-gene product trans-activates both RNA polymerase II and III promoters, EMBO J, 9, 497, 10.1002/j.1460-2075.1990.tb08136.x

Hu, 1990, Trans-activation of HLA-DR gene by hepatitis B virus X gene product, Proc Natl Acad Sci U S A, 87, 7140, 10.1073/pnas.87.18.7140

Hohne, 1990, Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA, EMBO J, 9, 1137, 10.1002/j.1460-2075.1990.tb08220.x

Kim, 1991, HBx gene of hepatitis B virus induces liver cancer in transgenic mice, Nature, 351, 317, 10.1038/351317a0

Siddiqui, 1987, Expression of the hepatitis B virus X gene in mammalian cells, Proc Natl Acad Sci U S A, 84, 2513, 10.1073/pnas.84.8.2513

Qadri, 1995, Hepatitis B virus transactivator protein X interacts with the TATA-binding protein, Proc Natl Acad Sci U S A, 92, 1003, 10.1073/pnas.92.4.1003

Cheong, 1995, Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation, EMBO J, 14, 143, 10.1002/j.1460-2075.1995.tb06984.x

Maguire, 1991, HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions, Science, 252, 842, 10.1126/science.1827531

Lee, 1995, Hepatitis B virus X protein interacts with a probable cellular DNA repair protein, J Virol, 69, 1107, 10.1128/JVI.69.2.1107-1114.1995

Wang, 1994, Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3, Proc Natl Acad Sci U S A, 91, 2230, 10.1073/pnas.91.6.2230

Cross, 1993, Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases, Proc Natl Acad Sci U S A, 90, 8078, 10.1073/pnas.90.17.8078

Kekule, 1993, Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway, Nature, 361, 742, 10.1038/361742a0

Doria, 1995, The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors, EMBO J, 14, 4747, 10.1002/j.1460-2075.1995.tb00156.x

Feng, 1995, The RNA component of human telomerase, Science, 269, 1236, 10.1126/science.7544491

Harrington, 1997, A Mammalian telomerase-associated protein, Science, 275, 973, 10.1126/science.275.5302.973

Nakayama, 1997, TLP1, Cell, 88, 875, 10.1016/S0092-8674(00)81933-9

Nakamura, 1997, Telomerase catalytic subunit homologs from fission yeast and human, Science, 277, 955, 10.1126/science.277.5328.955

Meyerson, 1997, hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization, Cell, 90, 785, 10.1016/S0092-8674(00)80538-3

Zhou, 2000, Effects of hepatitis B virus X gene on apoptosis and the activity of telomerase in HepG2 cells, Chin J Hepatol, 4, 212

Kim, 1994, Specific association of human telomerase activity with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428

Twu, 1987, Transcriptional trans-activating function of hepatitis B virus, J Virol, 61, 3448, 10.1128/JVI.61.11.3448-3453.1987

Elmore, 1997, Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis, Proc Natl Acad Sci U S A, 94, 14707, 10.1073/pnas.94.26.14707

Shih, 2000, Hepatitis B virus X protein inhibits transforming growth factor-beta-induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway, J Biol Chem, 275, 25858, 10.1074/jbc.M003578200

Kotoula, 2002, Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers, Liver, 22, 57, 10.1046/j.0106-9543.2001.01594.x

Harada, 2001, PCR and in situ hybridization studies of telomerase subunits in human non-neoplastic livers, J Pathol, 193, 210, 10.1002/1096-9896(2000)9999:9999<::AID-PATH786>3.0.CO;2-G

Soder, 1997, Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer, Oncogene, 14, 1013, 10.1038/sj.onc.1201066

Hiyama, 1998, In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesinons, Jpn J Cancer Res, 89, 1187, 10.1111/j.1349-7006.1998.tb00514.x

Wang, 1998, Myc activates telomerase, Gene Dev, 12, 1769, 10.1101/gad.12.12.1769

Nozawa, 2001, Mechanism for the reduction of telomerase expression during muscle cell differentiation, J Biol Chem, 276, 22016, 10.1074/jbc.M011181200

Wick, 1999, Genomic organization and promotor characterization of the gene encoding the human telomerase reverse transciptase (TERT), Gene, 232, 97, 10.1016/S0378-1119(99)00108-0