Effects of celecoxib on major prostaglandins in asthma

Vane, 1971, Inhibition of prostaglandin biosynthesis as a mechanism of action for aspirin-like drugs, Nat New Biol, 231, 232, 10.1038/newbio231232a0

Kujubu, 1991, Herschman HR, TIS 10, a phorbol ester tumor promoterinducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue, J Biol Chem, 266, 12866, 10.1016/S0021-9258(18)98774-0

Masferrer, 1992, Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme, Proc Natl Acad Sci USA, 89, 3917, 10.1073/pnas.89.9.3917

Rovati, 2010, Dual COXIB/TP antagonists, a possible new twist in NSAID pharmacology and cardiovascular risk, 31, 102

McAdam, 1999, Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2, the human pharmacology of a selective inhibitor of COX-2, 96, 272

Grosser, 2010, Emotion recollected in tranquility; lessons from the COX-2 saga, Ann Rev Med, 61, 17, 10.1146/annurev-med-011209-153129

Pavord, 1995, Bronchoprotective role for endogenous prostaglandin E2, Lancet, 345, 436, 10.1016/S0140-6736(95)90409-3

Curzen, 1987, Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man, Thorax, 42, 946, 10.1136/thx.42.12.946

Sladek, 1990, Allergen-stimulated release of thromboxane A2 and leukotriene E4 in humans. Effect of indomethacin, Am Rev Respir Dis, 141, 1441, 10.1164/ajrccm/141.6.1441

Sestini, 1999, Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses, Am J Respir Crit Care Med, 159, 1228, 10.1164/ajrccm.159.4.9709045

Nizankowska-Mogilnicka, 2007, EAACI/GA2LEN guideline, aspirin provocation tests for diagnosis of aspirin hypersensitivity, 62, 1111

Saroea, 1995, U46619-induced bronchoconstriction in asthmatic subjects is mediated by acetylcholine release, Am J Respir Crit Care Med, 151, 321, 10.1164/ajrccm.151.2.7842185

Hardy, 1984, The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men, N Engl J Med, 311, 209, 10.1056/NEJM198407263110401

Pettipher, 2008, The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses, Br J Pharmacol, 153, S191, 10.1038/sj.bjp.0707488

Matsuoka, 2000, Prostaglandin D2 as a mediator of allergic asthma, Science, 287, 2013, 10.1126/science.287.5460.2013

Murakami, 1995, IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxide synthase-2, J Immunol, 155, 4445, 10.4049/jimmunol.155.9.4445

Shiraishi, 2008, Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation, J Immunol, 180, 541, 10.4049/jimmunol.180.1.541

Song, 2008, Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans, J Biol Chem, 283, 1179, 10.1074/jbc.M706839200

Fries, 2006, Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2, Gastroenterology, 130, 55, 10.1053/j.gastro.2005.10.002

Yoshida, 2000, Selective cyclo-oxygenase 2 inhibitor in patients with aspirin-induced asthma, J Allergy Clin Immunol, 106, 1201, 10.1067/mai.2000.110926

Szczeklik, 2001, Safety of a specific COX-2 inhibitor in aspirin-induced asthma, Clin Exp Allergy, 31, 219, 10.1046/j.1365-2222.2001.01075.x

Gyllfors, 2003, Biochemical and clinical evidence that aspirin-intolerant asthmatics tolerate the cyclooxygenase-2 (COX-2) selective analgetic drug celecoxib, J Allergy Clin Immunol, 111, 1116, 10.1067/mai.2003.1450

O'Sullivan, 1996, Increased urinary excretion of the prostaglandin D2 metabolite 9α,11β-prostaglandin F2 following aspirin challenge supports mastcell activation in aspirin-induced airway obstruction, J Allergy Clin Immunol, 98, 421, 10.1016/S0091-6749(96)70167-7

Gaber, 2008, Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma, Thorax, 63, 1076, 10.1136/thx.2008.101196

Bäck, 2007, The Oral Cavity and Age, a Site of Chronic Inflammation?, 2, e1351

Murphey, 2004, Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay, determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer, 334, 266

Mastalerz, 2008, Szczeklik A Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity, Thorax, 63, 27, 10.1136/thx.2007.080903

Yin, 2007, Urinary prostaglandin F2alpha is generated from the isoprostane pathway and not the cyclooxygenase in humans, J Biol Chem, 282, 329, 10.1074/jbc.M608975200

Dahlén, 2004, Monitoring mast cell activation by prostaglandin D2 in vivo, Thorax, 59, 453, 10.1136/thx.2004.026641

Obata, 1999, Eicosapentaenoic acid inhibits prostaglandin D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells, Clin Exp Allergy, 29, 1129, 10.1046/j.1365-2222.1999.00604.x

Patrono, 1986, Estimated rate of thromboxane secretion into the circulation of normal humans, J Clin Invest, 77, 590, 10.1172/JCI112341

O'Sullivan, 1998, Urinary excretion of inflammatory mediators during allergen-induced early and late phase asthmatic reactions, Clin Exp Allergy, 28, 1332, 10.1046/j.1365-2222.1998.00368.x

O'Sullivan, 1998, Evidence for mast cell activation during exercise-induced bronchoconstriction, Eur Respir J, 12, 345, 10.1183/09031936.98.12020345

Brannan, 2006, Inhibition of mast cell PGD2 release protects against mannitol-induced airway narrowing, Eur Respir J, 27, 944, 10.1183/09031936.06.00078205

Kumlin, 1992, Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4 and histamine in asthmatics, Am Rev Respir Dis, 146, 96, 10.1164/ajrccm/146.1.96

Kippelen, 2010, Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes, Med Sci Sports Exerc, 10.1249/MSS.0b013e3181da4f7d

Brightling, 2002, Mast-cell infiltration of airway smooth muscle in asthma, N Engl J Med, 346, 1699, 10.1056/NEJMoa012705

Smith, 2005, Use of exhaled nitric oxide measurements to guide treatment in chronic asthma, N Engl J Med, 352, 2163, 10.1056/NEJMoa043596

Higashi, 2002, A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma, Clin Exp Allergy, 32, 1484, 10.1046/j.1365-2745.2002.01507.x

Bochenek, 2003, A controlled study of 9α,11β-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge, J Allergy Clin Immunol, 111, 743, 10.1067/mai.2003.1387

Higashi, 2010, Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers, J Allergy Clin Immunol, 125, 1084, 10.1016/j.jaci.2009.12.977

Sebaldt, 1990, Inhibition of eicosanoid biosynthesis by glucocorticoids in humans, Proc Natl Acad Sci USA, 87, 6974, 10.1073/pnas.87.18.6974

Hamberg, 1972, Inhibition of prostaglandin synthesis in man, Biochem Biophys Res Commun, 49, 720, 10.1016/0006-291X(72)90470-6

Seyberth, 1976, Quantification of the major urinary metabolite of the E prostaglandins by mass spectrometry, evaluation of the method's application to clinical studies, 11, 381