Effectiveness factors for immobilized‐enzyme reactions

Canadian Journal of Chemical Engineering - Tập 50 Số 2 - Trang 162-167 - 1972
Murray Moo‐Young1, Takeshi Kobayashi1
1Department of Chemical Engineering University of Waterloo, Waterloo, Ontario

Tóm tắt

AbstractThe effect of intraparticle diffusion in artificial membranes on the kinetic behavior of immobilized enzymes has been considered theoretically in terms of an effectiveness factor. When the immobilized enxymes obey a Michaelis‐Menten relationship, an approximate equation is proposed for the effectiveness factor. For a substrate inhibited enzymatic reaction, the effectiveness factor may exceed unity and display multiple steady‐state behavior. Thus, the over‐all rate of reaction in the artificial membrane is faster in this case than that when the substrate concentration in the interior is at the same as that at the exterior surface. In the case of a product inhibited enzymatic reaction, the effectiveness factor is always less than that which corresponds to a Michaelis‐Menten relationship.

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Thông tin
Thông tin xuất bản

Canadian Journal of Chemical Engineering

Tập 50 Số 2

162-167

Thông tin tác giả