Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles
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Russell-Jones, 2004, Use of targeting agents to increase uptake and localization of drugs to the intestinal epithelium, J. Drug Target., 12, 113, 10.1080/10611860410001693760
Kennedy, 1991, Recent developments in insulin delivery techniques: current status and future potential, Drugs, 42, 213, 10.2165/00003495-199142020-00004
Marble, 1985, Joslin's Diabetes Mellitus, 843
Monaco, 1996, Accuracy of injection site identification among children with insulin dependent diabetes mellitus: a comparison of traditional and new visual aids, Clin. Pediatr., 35, 191, 10.1177/000992289603500403
Carlson, 1993, Intensive insulin therapy and weight gain in IDDM, Diabetes, 42, 1700, 10.2337/diabetes.42.12.1700
Onuki, 2004, Formulation optimization of water-in-oil-water multiple emulsion for intestinal insulin delivery, J. Control. Release, 97, 91, 10.1016/j.jconrel.2004.03.010
Toorisaka, 2003, Hypoglycemic effect of surfactant-coated insulin solubilized in a novel solid-in-oil-in-water (S/O/W) emulsion, Int. J. Pharm., 252, 271, 10.1016/S0378-5173(02)00674-9
Morçöl, 2004, Calcium phosphate-PEG-insulin-casein (CAPIC) particles as oral delivery systems for insulin, Int. J. Pharm., 277, 91, 10.1016/j.ijpharm.2003.07.015
Zhenqing, 2004, Use of natural plant exudates (Sanguis draxonis) for sustained oral insulin delivery with dramatic reductions of glycemic effects in diabetic rats, J. Control. Release, 97, 467, 10.1016/j.jconrel.2004.03.033
Carino, 2000, Nanosphere based oral insulin delivery, J. Control. Release, 65, 261, 10.1016/S0168-3659(99)00247-3
Chung, 2002, Self-assembled ”nanocubicle” as carrier for oral insulin delivery, Diabetologia, 45, 448, 10.1007/s00125-001-0751-z
Cui, 2006, Biodegradable nanoparticles loaded with insulin–phospholipid complex for oral delivery: preparation, in vitro characterization and in vivo evaluation, J. Control. Release, 114, 242, 10.1016/j.jconrel.2006.05.013
Damage, 1988, New approach for the oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carrier, Diabetes, 37, 246, 10.2337/diabetes.37.2.246
Tozaki, 1997, Chitosan capsules for colon-specific drug delivery: improvement of insulin absorption from the rat colon, J. Pharm. Sci., 89, 1016, 10.1021/js970018g
Takeuchi, 1996, Enteral absorption of insulin in rats from mucoadhesive chitosan-coated liposomes, Pharm. Res., 13, 896, 10.1023/A:1016009313548
Kisel, 2001, Liposomes with phosphatidylethanol as a carrier for oral delivery of insulin: studies in the rat, Int. J. Pharm., 216, 105, 10.1016/S0378-5173(01)00579-8
Fasano, 1997, Modulation of intestinal tight junctions by zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model, J. Clin. Invest., 99, 1158, 10.1172/JCI119271
Uchida, 2001, Preparation and characterization of insulin-loaded acrylic hydrogels containing absorption enhancers, Chem. Pharm. Bull., 49, 1261, 10.1248/cpb.49.1261
Yamamato, 1994, Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats, Pharm. Res., 11, 1496, 10.1023/A:1018968611962
Marschűtz, 2000, Design and in vivo evaluation of an oral delivery system for insulin, Pharm. Res., 17, 1468, 10.1023/A:1007696723125
Still, 2002, Development of oral insulin: progress and current status, Diabetes Metab. Res. Rev., S29, 10.1002/dmrr.207
Xia, 2000, Hypoglycemic effect of insulin-transferrin conjugate in streptozotocin-induced diabetic rats, J. Pharmacol. Exp. Ther., 295, 594
Uraizee, 2000, Development of a targeted mucoadhesive drug delivery system for the peroral administration of insulin, Drugs Made Ger., 43, 41
Pan, 2002, Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo, Int. J. Pharm., 249, 139, 10.1016/S0378-5173(02)00486-6
Musabayane, 2000, Orally administered, insulin-loaded amidated pectin hydrogel beadssustain plasma concentrations of insulin in streptozotocin–diabetic rats, J. Endocrinol., 164, 1, 10.1677/joe.0.1640001
Morishita, 2004, Mucosal insulin delivery systems based on complexation polymer hydrogels: effect of particle size on insulin eternal absorption, J. Control. Release, 97, 115, 10.1016/j.jconrel.2004.03.008
Chen, 1998, Oral particulate delivery: status and future trends, Adv. Drug Deliv. Rev., 34, 339, 10.1016/S0169-409X(98)00047-7
Russell-Jones, 1999, Vitamin B12 mediated transport of nanoparticles across Caco-2 cells, Int. J. Pharm., 179, 247, 10.1016/S0378-5173(98)00394-9
Russell-Jones, 1995, Synthesis of LHRH antagonists suitable for oral administration via vitamin B12 uptake system, Bioconjug. Chem., 6, 34, 10.1021/bc00031a600
Russell-Jones, 1995, Vitamin B12 mediated oral delivery systems for granulocyte-colony stimulating factor and erythropoietin, Bioconjug. Chem., 6, 459, 10.1021/bc00034a016
K.B. Chalasani, P.V. Diwan, K.V. Raghavan, G.J. Russell-Jones, S.K. Jain, K.K. Rao, Vitamin B12 — biodegradable micro particulate conjugate carrier systems for peroral delivery of drugs, therapeutic peptides/proteins and vaccines, (2002) US patient 6,482,413.
Chalasani, 2007, A novel vitamin B12 nanosphere conjugate carrier system for peroral delivery of insulin, J. Control. Release, 117, 421, 10.1016/j.jconrel.2006.12.003
Anton, 1980, Carbon-13 nuclear magnetic studies of monocarboxylic acid of cyanocobalamine. Assignments of b, d, and e-monocaroxylic acid, J. Am. Chem. Soc., 102, 2215, 10.1021/ja00527a011
D.S. Wilbur, P.M. Pathare, A.C. Morgan, Jr. Biotyinylated cobalamines, (1998) US PTO 5,739,287.
McEwan, 1999, Synthesis and biological activity of ribose-5'-carbamate derivatives of vitamin B12, Bioconjug. Chem., 10, 1131, 10.1021/bc990086p
A. D. Habberfield, O. B. Kinstler, C. G. Pitt, Conjugates of vitamin B12 and proteins, (1996) USPTO 5,574,018.
Peyrot, 1994, Supramolecular biovectors (SMBV): a new family of nano particulate drug delivery systems. Synthesis and characterization, Int. J. Pharm., 102, 25, 10.1016/0378-5173(94)90036-1
Illum, 2001, Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance nasal absorption of polypeptides, Int. J. Pharm., 222, 109, 10.1016/S0378-5173(01)00708-6
Kolhouse, 1977, Absorption plasma transport, and cellular retention of cobalamin analogues in the rabbit: evidence for the existence of multiple mechanisms that prevent the absorption and tissue dissemination of naturally occurring cobalamin analogues, J. Clin. Invest., 60, 1381, 10.1172/JCI108899
Park, 1993
Linnell, 1995, Inherited errors of cobalamin metabolism and their management, Bailliere's Clin. Haematol., 8, 567, 10.1016/S0950-3536(05)80221-5
Hillman, 1996, Hemopoiteic agents, growth factors, minerals and vitamins, 1310
Mesiha, 2002, Oral absorption of insulin encapsulated in artificial chyles of bile salts, palmitic acid and alpha-tocopherol dispersions, Int. J. Pharm., 249, 1, 10.1016/S0378-5173(02)00381-2
Whitehead, 2004, Oral delivery of macromolecules using intestinal patches: applications for insulin delivery, J. Control. Release, 98, 37, 10.1016/j.jconrel.2004.04.013
Kim, 2005, Bioadhesive interaction and hypoglycemic effect of insulin-loaded lectin-microparticle conjugates in oral insulin delivery system, J. Control. Release, 102, 525, 10.1016/j.jconrel.2004.10.032
Gwinup, 1991, Insulin and C-peptide levels following oral administration of insulin in intestinal-enzyme protected capsules, Gen. Pharmacol., 22, 243, 10.1016/0306-3623(91)90440-H
Lewis, 1996, Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans, Diabetes, 45, 454, 10.2337/diabetes.45.4.454