Effect of Nigella sativa and wheat germ oils on scopolamine-induced memory impairment in rats

Nie, 2009, Han JX Age-related decrease in constructive activation of Akt/PKB in SAMP10 hippocampus, Biochem Biophys Res Commun, 378, 103, 10.1016/j.bbrc.2008.11.010 Nicolakakis, 2008, Complete rescue of cerebrovascular function in aged Alzheimer’s disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, J Neurosci, 28, 9287, 10.1523/JNEUROSCI.3348-08.2008 Schliebs, 2005, Basal forebrain cholinergic dysfunction in Alzheimer’s disease–interrelationship with beta-amyloid, inflammation and neurotrophin signaling, Neurochem Res, 30, 895, 10.1007/s11064-005-6962-9 Watanabe, 2009, Decreased acetylcholine release is correlated to memory impairment in the Tg2576 transgenic mouse model of Alzheimer’s disease, Brain Res, 1249, 222, 10.1016/j.brainres.2008.10.029 Shen, 2004, Brain cholinesterases: II. The molecular and cellular basis of Alzheimer’s disease, Med Hypotheses, 63, 308, 10.1016/j.mehy.2004.02.031 Greig, 2002, Butyrylcholinesterase: an important new target in Alzheimer’s disease therapy, Int Psychogeriatr, 14, 77, 10.1017/S1041610203008676 Klinkenberg, 2010, The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies, Neurosci Biobehav Rev, 34, 1307, 10.1016/j.neubiorev.2010.04.001 El-Sherbiny, 2003, Eldenshary Eel, D. Hypericum perforatum extract demonstrates antioxidant properties against elevated rat brain oxidative status induced by amnestic dose of scopolamine, Pharmacol Biochem Behav, 76, 525, 10.1016/j.pbb.2003.09.014 Lee, 2009, Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice, Pharmacol Biochem Behav, 93, 121, 10.1016/j.pbb.2009.04.021 Chattipakorn, 2007, Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats, J Ethnopharmacol, 110, 61, 10.1016/j.jep.2006.09.007 Saxena, 2008, Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice, Eur J Pharmacol, 581, 283, 10.1016/j.ejphar.2007.12.009 Tabet, 2006, Acetylcholinesterase inhibitors for Alzheimer’s disease: anti-inflammatories in acetylcholine clothing!, Age Ageing, 35, 336, 10.1093/ageing/afl027 Hwang, 2010, Microglia signaling as a target of donepezil, Neuropharmacology, 58, 1122, 10.1016/j.neuropharm.2010.02.003 Ismail, 2010, Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats, Free Radic Biol Med, 48, 664, 10.1016/j.freeradbiomed.2009.12.002 Marsik, 2005, In vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1- and -2-catalyzed prostaglandin E2 biosyntheses, Planta Med, 71, 739, 10.1055/s-2005-871288 Smythies, 1999, The neurotoxicity of glutamate, dopamine, iron and reactive oxygen species: functional interrelationship in health and diseases, Neurotoxicol Res, 1, 27, 10.1007/BF03033337 Wang, 2001, Refining high-free fatty acid wheat germ oil, J Am Oil Chem Soc, 78, 71, 10.1007/s11746-001-0222-2 Shirpoor, 2009, Protective effect of vitamin E against ethanol-induced hyperhomocysteinemia, DNA damage, and atrophy in the developing male rat brain, Alcohol Clin Exp Res, 33, 1181, 10.1111/j.1530-0277.2009.00941.x Martinez Villayandre, 2004, Effect of vitamin E treatment on N-methyl-D-aspartate receptor at different ages in the rat brain, Brain Res, 1028, 148, 10.1016/j.brainres.2004.09.008 Lee, 2001, Effect of supplementation of vitamin E and vitamin C on brain acetylcholinesterase activity and neurotransmitter levels in rats treated with scopolamine, an inducer of dementia, J Nutr Sci Vitaminol (Tokyo), 47, 323, 10.3177/jnsv.47.323 Roldan, 1997, Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats, Neurosci Lett, 230, 93, 10.1016/S0304-3940(97)00489-8 Schreiber, 2007, Effects of the novel 5-HT(6) receptor antagonist RO4368554 in rat models for cognition and sensorimotor gating, Eur Neuropsychopharmacol, 17, 277, 10.1016/j.euroneuro.2006.06.009 Mohamadin, 2010, Abd El-Aal AA, Elberry AA, Al-Abbasi FA. Protective effects of Nigella sativa oil on propoxur-induced toxicity and oxidative stress in rat brain regions, Pestic Biochem Physiol, 98, 128, 10.1016/j.pestbp.2010.05.011 Mehranjani, 2007, Preventing effects of wheat germ oil on sex hormones, liver enzymes, lipids and proteins in rat serum following treatment with p-nonylphenol, J Biol Sci, 7, 1406, 10.3923/jbs.2007.1406.1411 Wiley, 2003, Pharmacological challenge reveals long-term effects of perinatal phencyclidine on delayed spatial alternation in rats, Prog Neuropsychopharmacol Biol Psychiatry, 27, 867, 10.1016/S0278-5846(03)00146-5 Tsaltas, 2007, Enhancing effects of chronic lithium on memory in the rat, Behav Brain Res, 177, 51, 10.1016/j.bbr.2006.11.003 Cacucci, 2008, Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model, Proc Natl Acad Sci U S A, 105, 7863, 10.1073/pnas.0802908105 Jones, 2006, Guidelines for statistical analysis of percentage of syllables stuttered data, J Speech Lang Hear Res, 49, 867, 10.1044/1092-4388(2006/062) Ennaceur, 1988, A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data, Behav Brain Res, 31, 47, 10.1016/0166-4328(88)90157-X Ruiz-Larrea, 1994, Antioxidant effects of estradiol and 2-hydroxyestradiol on iron-induced lipid peroxidation of rat liver microsomes, Steroids, 59, 383, 10.1016/0039-128X(94)90006-X Ellman, 1959, Tissue sulfhydryl groups, Arch Biochem Biophys, 82, 70, 10.1016/0003-9861(59)90090-6 Bulaj, 1998, Ionization-reactivity relationships for cysteine thiols in polypeptides, Biochemistry, 37, 8965, 10.1021/bi973101r Den Blawen, 1983, J Clin Chem Biochem, 21, 381 Tian, 2005, A TNF-induced gene expression program under oscillatory NF-kappaB control, BMC Genomics, 6, 137, 10.1186/1471-2164-6-137 Eidi, 2006, Effect of vitamin E on memory retention in rats: possible involvement of cholinergic system, Eur Neuropsychopharmacol, 16, 101, 10.1016/j.euroneuro.2005.06.006 Cantuti-Castelvetri, 2000, Neurobehavioral aspects of antioxidants in aging, Int J Dev Neurosci, 18, 367, 10.1016/S0736-5748(00)00008-3 Hughes, 2010, Enhanced habituation and decreased anxiety by environmental enrichment and possible attenuation of these effects by chronic alpha-tocopherol (vitamin E) in aging male and female rats, Pharmacol Biochem Behav, 94, 534, 10.1016/j.pbb.2009.11.008 Blokland, 1996, Acetylcholine: a neurotransmitter for learning and memory?, Brain Res Rev, 21, 285, 10.1016/0165-0173(95)00016-X Reddy, 2009, Oxidative stress in diabetes and Alzheimer’s disease, J Alzheimers Dis, 16, 763, 10.3233/JAD-2009-1013 Sharma, 2001, Effect of chronic treatment of melatonin on learning, memory and oxidative deficiencies induced by intracerebroventricular streptozotocin in rats, Pharmacol Biochem Behav, 70, 325, 10.1016/S0091-3057(01)00611-6 Sharma, 2001, Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment, Life Sci, 68, 1021, 10.1016/S0024-3205(00)01005-5 Hosseinzadeh, 2007, Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus, Phytomedicine, 14, 621, 10.1016/j.phymed.2006.12.005 Cruz, 2005, Glutathione in cognitive function and neurodegeneration, Rev Neurol, 36, 877 Shireen, 2008, Effects of dietary vitamin E, C and soybean oil supplementation on antioxidant enzyme activities in liver and muscles of rats, Food Chem Toxicol, 46, 3290, 10.1016/j.fct.2008.07.015 Yanardag, 2007, Combined effects of vitamin C, vitamin E, and sodium selenate supplementation on absolute ethanol-induced injury in various organs of rats, Int J Toxicol, 26, 513, 10.1080/10915810701707296 Ciocoiu, 2007, Protecting antioxidative effects of vitamins E and C in experimental physical stress, J Physiol Biochem, 63, 187, 10.1007/BF03165781 Behl, 2002, Antioxidant neuroprotection in Alzheimer’s disease as preventive and therapeutic approach, Free Radic Biol Med, 33, 182, 10.1016/S0891-5849(02)00883-3 Cerbai, 2007, N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine, Eur J Pharmacol, 572, 142, 10.1016/j.ejphar.2007.06.053 Ismail, 2008, Black cumin seed (Nigella sativa Linn.) oil and its fractions protect against beta amyloid peptide-induced toxicity in primary cerebellar granule neurons, J Food Lipids, 15, 519, 10.1111/j.1745-4522.2008.00137.x Delwing-de Lima, 2010, Guanidino compounds inhibit acetylcholinesterase and butyrylcholinesterase activities: effect neuroprotector of vitamins E plus C, Int J Dev Neurosci, 28, 465, 10.1016/j.ijdevneu.2010.06.008 Greig, 2005, Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent, Proc Natl Acad Sci U S A, 102, 17213, 10.1073/pnas.0508575102 Wang, 2005, Beta-amyloid inhibition of long-term potentiation is mediated via tumor necrosis factor, Eur J Neurosci, 22, 2827, 10.1111/j.1460-9568.2005.04457.x Rowan, 2007, Synaptic memory mechanisms: Alzheimer’s disease amyloid beta-peptide-induced dysfunction, Biochem Soc Trans, 35, 1219, 10.1042/BST0351219 Al-Majed, 2006, Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus, Eur J Pharmacol, 543, 40, 10.1016/j.ejphar.2006.05.046 Sung, 2004, Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer’s disease, FASEB J, 18, 323, 10.1096/fj.03-0961fje