EFFECT OF COLD EXPOSURE ON RESPIRATORY C<sup>14</sup>O<sub>2</sub>PRODUCTION DURING INFUSION OF ALBUMIN-BOUND PALMITATE-1-C<sup>14</sup>IN WHITE RATS

Canadian Science Publishing - Tập 39 Số 2 - Trang 219-224 - 1961
R Masironi, Florent Depocas

Tóm tắt

Albumin palmitate-1-C14complex was infused at a constant rate through a carotid cannula (inserted 5–7 days earlier) into otherwise intact non-fasted rats in environments at 30° or 6 °C, after acclimation to 30° or 6 °C. At 6 °C, both warm- and cold-acclimated rats similarly exhaled as CI4O2a larger proportion of the injected C14and gave lower terminal amounts of C14in the extracted free fatty acids (F.F.A.) of plasma than at 30 °C. These results indicate that plasma F.F.A. serve as substrate for cold-thermogenesis. Also, increased turnover and oxidation of F.F.A. are not always inversely related to carbohydrate utilization but may be increased under conditions which result in concomitantly higher rates of turnover and oxidation of glucose.

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Tài liệu tham khảo

FREDERICKSON R. S., 1958, JR. Physiol. Revs., 38, 585, 10.1152/physrev.1958.38.4.585

V. POPOVIC P., 1960, J. Appl. Physiol., 15, 727, 10.1152/jappl.1960.15.4.727

MASORO J. M., 1958, J. Biol. Chem., 231, 347, 10.1016/S0021-9258(19)77311-6

GORDON, 1957, JR. J. Clin. Invest., 36, 810, 10.1172/JCI103486

LAURELL., 1959, Acta Physiol. Scand., 47, 218, 10.1111/j.1748-1716.1960.tb00072.x

FREDERICKSON R. S., 1958, JR. J. Clin. Invest., 37, 1504, 10.1172/JCI103742

GORDON JR., 1956, J. Clin. Invest., 35, 206, 10.1172/JCI103265

LAURELL J., 1956, Lab. Invest., 8, 81, 10.3109/00365515609049249

DOI E., 1956, J. Clin. Invest., 35, 150, 10.1172/JCI103259

ELLIS., 1956, Pharmacol. Revs., 8, 485

GORDON JR., 1958, Proc. Soc. Exptl. Biol. Med., 97, 150, 10.3181/00379727-97-23672

WHITE F. L., 1958, Proc. Soc. Exptl. Biol. Med., 99, 375, 10.3181/00379727-99-24355

HSIEH L. D., 1957, CARLSON. Am. J. Physiol., 190, 243, 10.1152/ajplegacy.1957.190.2.243

EPOCAS J ., 1960, Physiol., 38, 107